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ENO1


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Symbol:ENO1
Name(s):enolase 1, (alpha)
Type:protein-coding
Organism:Homo sapiens
Synonyms:ENO1L1, MBP-1, MPB1, NNE, PPH
Links: Pubmed, Entrez Gene, GeneCards, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17996313 alpha-enolase and MBP-1 associate with the kelch protein NS1-BP. c-Myc gene transcriptional repression exerted by MBP-1 is enhanced by NS1-BP.
17996313 These findings further support the distinct roles of alpha-enolase and its MBP-1 variant in maintaining cell homeostasis. Moreover, these data suggest a novel function for NS1-BP in the control of cell proliferation.
18070418 TGF-beta1-induced growth arrest was associated with notable downregulation of the myc-binding protein-1 (MBP-1).
18033204 Enolase on the surface of cells may be a receptor for plasminogen. The enolase/plasminogen (plasmin) system is one of the mechanisms facilitating the invasiveness of pathogens and it plays a role in myogenesis and in the development of tumor tissues.
12787059 A target of excess protein nitration in Alzheimer disease (AD) brain, providing evidence of the importance of oxidative stress in AD progression
15324934 antibodies against human alpha-enolase target antigens in retinal ganglion cells and inner nuclear layer cells and induce the apoptotic death of sensitive cells in rat retinal explants
15805119 Results suggest a novel role of c-myc promoter-binding protein 1 for suppression of prostate cancer cell growth by regulating the MEK5-mediated signaling pathway.
16359544 ENO1 has tumour suppressor activity and high level of ENO1 expression has growth inhibitory effects
17387692 alpha-crystallin B, glyceraldehyde phosphate dehydrogenase (GAPDH), and alpha-enolase identified as significantly S-glutathionylated in Alzheimer's disease infeior parietal lobule
12297304 Proteomic analysis of human brain identifies alpha-enolase as a novel autoantigen in Hashimoto's encephalopathy.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDenolase 1mitogen-activated protein kinase kinase kinase 7 isoform B--Pubmed

Recent Publications on ENO1:

Pubmed Logo
Novel Ree1 regulates the expression of ENO1 via the Snf1 complex pathway in Saccharomyces cerevisiae.
Using cDNA microarray analysis, we found that the mRNA of YJL217W and...
15th October, 2008
School of Life Sciences and Biotechnology, Korea University, Anam-dong Biochem Biophys Res Commun. 2008 Oct 11.
DOI Direct Link
Constructing disease-specific gene networks using pair-wise relevance metric: application to colon cancer identifies interleukin 8, desmin and enolase 1 as the central elements.
BACKGROUND: With the advance of large-scale omics technologies, it is now...
14th October, 2008
College of Bioinformatics Science and Technology and Bio-pharmaceutical BMC Syst Biol. 2008 Aug 10;2:72.
DOI Direct Link
Synthetic glycopeptide vaccines combining beta-mannan and peptide epitopes induce protection against candidiasis.
The first fully synthetic glycopeptide vaccines against a fungal disease...
1st October, 2008
Department of Pediatrics, Louisiana State University Health Sciences Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13526-31. Epub 2008 Aug 25.
DOI Direct Link
Glycolysis module activated by hypoxia-inducible factor 1alpha is related to the aggressive phenotype of hepatocellular carcinoma.
An increased level of glycolysis, an intracellular hallmark of neoplasms,...
25th September, 2008
Department of Digestive Surgery, Yamaguchi University Graduate School of Int J Oncol. 2008 Oct;33(4):725-31.
Synovial fluid is a site of citrullination of autoantigens in inflammatory arthritis.
OBJECTIVE: To examine synovial fluid as a site for generating...
19th September, 2008
Imperial College London, London, UK. Arthritis Rheum. 2008 Aug;58(8):2287-95.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
5882914 Nucleic acids encoding the hypoxia inducible factor-1
6432927 Compositions and methods for inducing gene expression
6451547 Process for differential diagnosis of Alzheimer's dementia and device therefor
6495130 Target cell-specific adenoviral vectors containing E3 and methods of use thereof
6569432 Prostate-specific membrane antigen and uses thereof

View more patents.

ENO1 results (if any) from reagent suppliers

Google CSE Logo
ENO1 antibody, ENO1 (enolase 1. (alpha)) Antibody, Rabbit IgG ...
Buy quality rabbit ENO1 antibody (interacts with human), anti-ENO1, ENO1 ( enolase 1. (alpha)) antibody, rabbit igg polyclonal antibody, ENO1 (enolase 1.
http://www.genwaybio.com/product_info.php?products_id=42514...

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ENO1 antibody (ab54979) datasheet | Abcam
Mouse monoclonal to ENO1. ENO1 encodes one of three enolase isoenzymes found in mammals; it encodes alpha-enolase, a homodimeric soluble enzyme, ...
http://www.abcam.com/index.html?datasheet=54979...

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ENO1 antibody, Alpha-enolase Antibody, Chicken IgY Polyclonal
Unable to connect to database server!
http://www.genwaybio.com/product_info.php?products_id=602...

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ENO1 antibodies | Abcam
ENO1 antibodies. ... ENO1 antibody. IHC-P, WB, ELISA, IHC-Fr. Images · Customer Abreviews: 3 stars (out of 5) Customer Abreviews: 3 stars (out of 5) ...
http://www.abcam.com/index.html?t=151601&pt=1&c=3580...

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Antibody to Neuron specific enolase by EnCor Biotechnology Inc ...
It is one of three mammalian enolases, which are also known as ENO1, ENO2, ... ENO1 is also known as enolase alpha and as non-neuronal enolase. ...
http://www.encorbio.com/rpolyclonal/RPCA-NSE.htm...

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Enolase (C-19) Antibody sc-7455
Mouse, Eno1, 13806, 4 E2, P17182, N/A. Mouse, Eno2, 13807, 6 F2, P17183, N/A. Mouse, Eno3, 13808, 11 B3, P21550, N/A. Ordering Information ...
http://www.scbt.com/datasheet-7455-enolase-c-19-antibody.htm...

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New Antibodies :: ProSci Incorporated
ENO1 Antibody · EphA1 Monclonal Antibody · EphrinB Antibody · EphrinB Antibody · EphrinB Antibody · ERBB3 Antibody · ESE-1 Antibody · ESE-1 Antibody ...
http://www.prosci-inc.com/new-antibodies.php...

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Primary Antibodies - GenWay Biotech Inc.
ENO1; ENO1L1, MBP-1, MPB1, NNE, PPH - EC 4.2.1.11; Enolase 1; Enolase, IgG Polyclonal WB, Source: Rabbit Reactivity: Human ...
https://www.genwaybio.com/all_primary_antibodies.php?fl=E&so...

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α Enolase (L-27) Antibody sc-100812
ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, ENO1, 2023, 1p36.23, NM_001428 · P06733 ...
http://www.scbt.com/datasheet-100812-alpha-enolase-l-27-anti...

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Cell Biology - Protein and Antibody Solutions Provider - GenWay
ENO1; ENO1L1; MBPB1; MPB1; NNE; PPH - EC 4.2.1.11; 2-phospho-D-glycerate hydro- lyase; Non-neural enolase; NNE; Enolase 1; Phosphopyruvate hydratase; ...
https://www.genwaybio.com/index.php?cPath=4003&fl=A...

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