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ENO1


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Symbol:ENO1
Name(s):enolase 1, (alpha)
Type:protein-coding
Organism:Homo sapiens
Synonyms:ENO1L1, MBP-1, MPB1, NNE, PPH
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17996313 alpha-enolase and MBP-1 associate with the kelch protein NS1-BP. c-Myc gene transcriptional repression exerted by MBP-1 is enhanced by NS1-BP.
17996313 These findings further support the distinct roles of alpha-enolase and its MBP-1 variant in maintaining cell homeostasis. Moreover, these data suggest a novel function for NS1-BP in the control of cell proliferation.
18070418 TGF-beta1-induced growth arrest was associated with notable downregulation of the myc-binding protein-1 (MBP-1).
18033204 Enolase on the surface of cells may be a receptor for plasminogen. The enolase/plasminogen (plasmin) system is one of the mechanisms facilitating the invasiveness of pathogens and it plays a role in myogenesis and in the development of tumor tissues.
12787059 A target of excess protein nitration in Alzheimer disease (AD) brain, providing evidence of the importance of oxidative stress in AD progression
15324934 antibodies against human alpha-enolase target antigens in retinal ganglion cells and inner nuclear layer cells and induce the apoptotic death of sensitive cells in rat retinal explants
15805119 Results suggest a novel role of c-myc promoter-binding protein 1 for suppression of prostate cancer cell growth by regulating the MEK5-mediated signaling pathway.
16359544 ENO1 has tumour suppressor activity and high level of ENO1 expression has growth inhibitory effects
17387692 alpha-crystallin B, glyceraldehyde phosphate dehydrogenase (GAPDH), and alpha-enolase identified as significantly S-glutathionylated in Alzheimer's disease infeior parietal lobule
12297304 Proteomic analysis of human brain identifies alpha-enolase as a novel autoantigen in Hashimoto's encephalopathy.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDenolase 1mitogen-activated protein kinase kinase kinase 7 isoform B--Pubmed

Recent Publications on ENO1:

Pubmed Logo
Effect of menopause on gene expression pattern in bone tissue of nonosteoporotic women.
OBJECTIVE: Menopausal changes influence the growth, differentiation, and...
29th October, 2009
1st Department of Internal Medicine, Semmelweis University, Budapest, Menopause. 2009 Mar-Apr;16(2):367-77.
DOI Direct Link
Identification of ATP citrate lyase as a positive regulator of glycolytic function in glioblastomas.
Glioblastomas, the most malignant type of glioma, are more glycolytic than...
2nd October, 2009
Department of Pathology, University of Pittsburgh, Pittsburgh, PA, 15213. Int J Cancer. 2009 Sep 30.
DOI Direct Link
Extracorporeal shock-wave therapy enhanced wound healing via increasing topical blood perfusion and tissue regeneration in a rat model of STZ-induced diabetes.
Extracorporeal shock-wave therapy (ESWT) has a significant positive effect...
25th September, 2009
Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Wound Repair Regen. 2009 Jul-Aug;17(4):522-30.
DOI Direct Link
Silencing of tachyzoite enolase 2 alters nuclear targeting of bradyzoite enolase 1 in Toxoplasma gondii.
In Toxoplasma gondii, an intracellular parasite of the phylum Apicomplexa,...
23rd September, 2009
Department of Chemistry and Biochemistry, University of Windsor, 401 Microbes Infect. 2009 Sep 19.
DOI Direct Link
Association of neonatal hypoxia with lasting changes in left ventricular gene expression: an animal model.
OBJECTIVE: Innovations in pediatric cardiovascular surgery have resulted...
19th September, 2009
Division of Cardiovascular Surgery, Montreal Children's Hospital-McGill J Thorac Cardiovasc Surg. 2009 Sep;138(3):538-46, 546.e1.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
6420529 Genetic selection method for identifying ligands for transmembrane proteins
7026121 Methods and compositions for diagnosing and monitoring transplant rejection
7037647 Prostate-specific membrane antigen and uses thereof
7052915 Selective labeling and isolation of phosphopeptides and applications to proteome analysis
7053062 Compositions and methods for inducing gene expression

View more patents.

ENO1 results (if any) from reagent suppliers

Google CSE Logo
Non Neuronal Enolase antibody (ab54979) | Abcam
Non Neuronal Enolase (ENO1) is an isoform of mammalian enolase and is composed of 2 alpha subunits. The gene for ENO1 encodes alpha-enolase, a homodim...
http://www.abcam.com/Non-Neuronal-Enolase-antibody-ab54979.h...

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ENO1 antibody, Alpha-enolase Antibody, Chicken IgY Polyclonal ...
This product is temporary unavailable. Continue. Exact | Advanced Search. Specific Categories. Antibodies · Secondary Antibodies ...
http://www.genwaybio.com/product_info.php?products_id=602...

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ENOA Antibody (C-term)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ENO1. Other Names
: ...
http://www.abgent.com/products/catalog_no/AP2879b_ENOA_Antib...

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Antibody to Neuron specific enolase by EnCor Biotechnology Inc ...
It is one of three mammalian enolases, which are also known as ENO1, ENO2, ... ENO1 is also known as enolase alpha and as non-neuronal enolase. ...
http://www.encorbio.com/rpolyclonal/RPCA-NSE.htm...

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Enolase (C-19) Antibody sc-7455
Mouse, Eno1, 13806, 4 E2, P17182, N/A. Mouse, Eno2, 13807, 6 F2, P17183, N/A. Mouse, Eno3, 13808, 11 B3, P21550, N/A. Ordering Information ...
http://www.scbt.com/datasheet-7455-enolase-c-19-antibody.htm...

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Abgent - Translation and Regulation Antibodies ...
AT1908aNEW, ENO1 monoclonal antibody (M01), ELISA,IF,IHC-P,S-ELISA,WB-Ce,WB-Re, WB-Tr, H. AT1909aNEW, ENO1 monoclonal antibody (M03), ELISA,S-ELISA,WB-Ce,WB-
...
http://www.abgent.com/products/category/nuclear_signaling/tr...

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Mbp antibody, MAb Oligodendrocytes & Myelin Antibody, Mouse ...
ENO1 (enolase 1. (alpha)), IgG · Amyloid Precursor Protein Frameshift Mutant, IgG · Myelin basic protein [B103.1], IgG · PRG2 [1.B.787], IgG Native_Protein
...
http://www.genwaybio.com/product_info.php?products_id=240133...

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