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AKT1
| Symbol: | AKT1 | | Name(s): | v-akt murine thymoma viral oncogene homolog 1 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17921701 |
A novel point mutation (E17K) in the pleckstrin homology domain (PHD) of the AKT1 gene in human cancers was discussed. |
| 18198266 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18182859 |
These results suggest that 0.05 Gy of ionizing radiation stimulates cell proliferation through the transient activation of Raf and Akt in CCD-18 Lu cells. |
| 18174256 |
RIG1 plays a role in IFN-gamma-mediated therapy by downregulating p185 and its downstream PI3K/Akt/mTOR/VEGF-signaling pathway |
| 18264090 |
the Akt/Girdin signalling pathway is essential in VEGF-mediated postneonatal angiogenesis |
| 18048359 |
a key regulatory role of the Akt/mTOR pathway in the generation of the effects of As(2)O(3) |
| 17906677 |
Enhanced angiotensin converting enzyme 2 regulates the insulin/Akt signalling pathway by blockade of macrophage migration inhibitory factor expression. |
| 18197291 |
Treatment of cells with arsenite also induced significant activation of PI-3K and Akt, which was responsible for the anchorage-independent cell growth induced by arsenite exposure. |
| 18083769 |
The activation of the protein kinase B (Akt) signaling cascade by carbon nanoparticles was investigated with regard to its relevance for proliferation. |
| 17977950 |
Impaired insulin signaling through Akt and AS160 in part explains insulin resistance at the molecular level in skeletal muscle in polycystic ovary syndrome. | →View more information from publications. |
Recent Publications on AKT1: |  |
Phosphatidylinositol 4,5-bisphosphate (PIP(2))-specific AKT1 is oncogenic.
The protein kinase AKT1 (v-akt murine thymoma viral oncogene homologue 1),... | 31st October, 2009
| The Scripps Research Institute, Molecular and Experimental Medicine, 10550
| Int J Cancer. 2009 Oct 28.
DOI Direct Link |
The Inhibition of PI3K-Akt Pathway Enhances Gamma-2 Herpesvirus Lytic Replication and Facilitates Reactivation from Latency.
Cellular signaling pathways are critical in regulating the balance between... | 30th October, 2009
| UCLA;
| J Gen Virol. 2009 Oct 28.
DOI Direct Link |
Tumor Necrosis Factor-Like Weak Inducer of Apoptosis Stimulation of Glioma Cell Survival Is Dependent on Akt2 Function.
Malignant gliomas are the most common primary brain tumors. Despite... | 29th October, 2009
| 2Diabetes, Cardiovascular and Metabolic Diseases Division, 3Integrated
| Mol Cancer Res. 2009 Oct 27.
DOI Direct Link |
AKT1 pleckstrin homology domain E17K activating mutation in endometrial carcinoma.
OBJECTIVES: The PI3K/AKT pathway is frequently activated in endometrial... | 27th October, 2009
| Department of Obstetrics and Gynecology, Sheba Medical Center,
| Gynecol Oncol. 2009 Oct 21.
DOI Direct Link |
Molecular mechanism underlying muscle mass retention in hibernating bats: Role of periodic arousal.
Hibernators like bats show only marginal muscle atrophy during prolonged... | 23rd October, 2009
| Division of Biological Science and Technology, College of Science and
| J Cell Physiol. 2009 Oct 21.
DOI Direct Link |
→View more research publications. |
AKT1 results (if any) from reagent suppliers | 
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