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AKT2
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18048359 |
a key regulatory role of the Akt/mTOR pathway in the generation of the effects of As(2)O(3) |
| 17372934 |
Changes in tissue pressure during inflammation may regulate macrophage phagocytosis by activation of PI-3K, which activates Akt2, mTOR, and p70S6K. |
| 18281467 |
Functional convergence of Twist and AKT2 underscores the importance of this signaling pathway in tumor development and progression. |
| 17914025 |
Akt1 and Akt2 mediate GPIb-IX signaling via the cGMP-dependent signaling pathway. |
| 17327441 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17576055 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17825284 |
Pressure did not stimulate translocation of AKT2 to the plasma membrane. |
| 17908691 |
Akt2 is required for rapamycin-induced vascular smooth muscle cell differentiation, whereas Akt1 appears to oppose contractile protein expression. |
| 17895832 |
PKB[alpha] and/or PKB[gamma] and not PKB[beta] alone are involved in gemcitabine resistance mechanisms. |
| 17804734 |
AKT2 up-regulation is characteristic of skin squamous cell carcinoma and coincident AKT2 activation through serine phosphorylation correlates with malignancy. | →View more information from publications. |
Interacting gene products |
| Interaction Type |
Gene 1 |
Gene 2 |
Interaction description |
Complex |
Publication Link |
| HPRD | Protein kinase B,beta | glucose transporter 4 | - | - | Pubmed |
| HPRD | Human rac protein kinase beta mRNA, and translated products | Solute carrier family 2 member 4 | - | - | Pubmed |
| HPRD | Human rac protein kinase beta mRNA, and translated products | follicle stimulating hormone receptor isoform 1 precursor | - | - | Pubmed |
| HPRD | Human rac protein kinase beta mRNA, and translated products | follicle stimulating hormone receptor isoform 1 precursor | - | - | Pubmed |
| HPRD | Human rac protein kinase beta mRNA, and translated products | conserved helix-loop-helix ubiquitous kinase | - | - | Pubmed |
| HPRD | Human rac protein kinase beta mRNA, and translated products | conserved helix-loop-helix ubiquitous kinase | - | - | Pubmed |
| HPRD | Human rac protein kinase beta mRNA, and translated products | glycogen synthase kinase 3 beta | - | - | Pubmed |
| HPRD | Human rac protein kinase beta mRNA, and translated products | glycogen synthase kinase 3 beta | - | - | Pubmed |
| HPRD | Human rac protein kinase beta mRNA, and translated products | T-cell leukemia/lymphoma 1B | - | - | Pubmed |
| HPRD | Human rac protein kinase beta mRNA, and translated products | T-cell leukemia/lymphoma 1B | - | - | Pubmed |
Recent Publications on AKT2: |  |
Tumor Necrosis Factor-Like Weak Inducer of Apoptosis Stimulation of Glioma Cell Survival Is Dependent on Akt2 Function.
Malignant gliomas are the most common primary brain tumors. Despite... | 29th October, 2009
| 2Diabetes, Cardiovascular and Metabolic Diseases Division, 3Integrated
| Mol Cancer Res. 2009 Oct 27.
DOI Direct Link |
Diverse prognostic roles of Akt isoforms, PTEN and PI3K in tumor epithelial cells and stromal compartment in non-small cell lung cancer.
AIM: By tissue microarray methodology, the expression of altered Akt... | 23rd October, 2009
| Institute of Medical Biology, University of Tromso, Norway.
| Anticancer Res. 2009 Oct;29(10):4175-83.
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AKT2 is a downstream target of metabotropic glutamate receptor 1 (mGlu1).
Summary We reported earlier on the oncogenic properties of Grm1 by... | 22nd October, 2009
| Susan Lehman Cullman Laboratory for Cancer Research, Department of
| Pigment Cell Melanoma Res. 2009 Oct 20.
DOI Direct Link |
MicroRNAs differentially regulated by Akt isoforms control EMT and stem cell renewal in cancer cells.
Although Akt is known to play a role in human cancer, the relative... | 15th October, 2009
| Department of Biological Chemistry and Molecular Pharmacology, Harvard
| Sci Signal. 2009 Oct 13;2(92):ra62.
DOI Direct Link |
Somatic mutations are present in all members of the AKT family in endometrial carcinoma.
Potassium-sodium interaction was compared in two natural accessions of... | 15th October, 2009
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| Br J Cancer. 2009 Oct 6;101(7):1218-9; author reply 1220-1. Epub 2009 Sep
DOI Direct Link |
→View more research publications. |
AKT2 results (if any) from reagent suppliers | 
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Search Bioportfolio and other Life Science Sites for AKT2,
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