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ESR1


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Symbol:ESR1
Name(s):estrogen receptor 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:DKFZp686N23123, ER, ESR, ESRA, Era, NR3A1
Links: Pubmed, Entrez Gene, GeneCards, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18097104 The ligand-binding domain is produced in Escherichia coli as a cleavable thioredoxin (Trx) fusion in order to improve solubility and the structure determined.
18202578 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18271972 Observational study of gene-disease association. (HuGE Navigator)
18285546 Observational study of gene-disease association. (HuGE Navigator)
18294052 Observational study of gene-disease association. (HuGE Navigator)
18301357 Observational study of gene-disease association. (HuGE Navigator)
18305958 Observational study of gene-disease association. (HuGE Navigator)
18309176 Observational study of gene-disease association. (HuGE Navigator)
18342444 Observational study of gene-disease association. (HuGE Navigator)
18350145 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDHomo sapiens chromosome 22estrogen receptor alpha isoform 1ER interacts with AP1B1.-Pubmed
HPRDaryl hydrocarbon receptorestrogen receptor 1--Pubmed
HPRDaryl hydrocarbon receptorestrogen receptor 1--Pubmed
HPRDAndrogen receptorestrogen receptor 1--Pubmed
HPRDandrogen receptor isoform 1Estrogen receptor alpha--Pubmed
HPRDandrogen receptor isoform 1Estrogen receptor, alpha--Pubmed
HPRDBCL2-associated athanogene isoform 1Lestrogen receptor 1--Pubmed
HPRDBCL2-associated athanogene isoform 1Lestrogen receptor 1--Pubmed
HPRDCyclin D1estrogen receptor 1--Pubmed
BINDHomo sapiens chromosome 11, reference assembly.estrogen receptor 1ER-alpha interacts with cyclin D1 promoter.-Pubmed

Recent Publications on ESR1:

Pubmed Logo
Estrogen receptor alpha gene polymorphism and breast cancer.
Estrogen and estrogen receptors play important roles in the proliferation...
29th October, 2008
Faculty of Medical Laboratory Technology, Sudan University for Science and Ann N Y Acad Sci. 2008 Sep;1138:95-107.
DOI Direct Link
Association between estrogen and androgen receptor genes and prostate cancer risk.
Objective: Prostate cancer (PC) is one of the principal causes of death...
28th October, 2008
N Nicolaiew, Institut Mondor de Medecine Moleculaire, Universite Paris 12, Eur J Endocrinol. 2008 Oct 24.
DOI Direct Link
Quantitative p16 and ESR1 methylation in the peripheral blood of patients with non-small cell lung cancer.
Inactivation of the p16 and ESR1 tumor suppressor genes by promoter lesion...
25th October, 2008
Department of Thoracic Surgery, Tokyo Medical University Hospital, Tokyo Oncol Rep. 2008 Nov;20(5):1137-42.
A candidate molecular signature associated with tamoxifen failure in primary breast cancer.
ABSTRACT: INTRODUCTION: Few markers are available to predict response to...
22nd October, 2008
Breast Cancer Res. 2008 Oct 17;10(5):R88.
DOI Direct Link
Characterization of Anti-Estrogenic Activity of the Chinese Herb, Prunella vulgaris, Using In Vitro and In Vivo (Mouse Xenograft) Models.
Prunella vulgaris (PV), a commonly used Chinese herb, also known as...
17th October, 2008
Biol Reprod. 2008 Oct 15.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
Fulvestrant (FASLODEX™) as a Treatment in Postmenopausal Women With Estrogen Receptor Positive Breast Cancer
Breast Cancer

Patents:

Patents logo
US Patent No.Title
6331393 Process for high-throughput DNA methylation analysis
6706867 DNA array sequence selection
6727063 Single nucleotide polymorphisms in genes
6747137 Nucleic acid sequences relating to Candida albicans for diagnostics and therapeutics
6806773 On-chip resistance to increase total equivalent series resistance

View more patents.

ESR1 results (if any) from reagent suppliers

Google CSE Logo
ESR1 estrogen receptor 1
ESR1; DKFZP686N23123; ER; ERA; ESR; ESRA; NR3A1. Refseq ID(s) ... HPA000449, Anti-ESR1 antibody produced in rabbit Ab1, Prestige Antibodies™ Powered by ...
http://www.sigmaaldrich.com/catalog/search/SIRNASearchGeneDe...

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Antibody Products - IgG Polyclonal Antibodies - GenWay
Mouse polyclonal antiserum to estrogen receptor alpha; 2099; ESR1; 133430; P03372; DKFZp686N23123; ER; ESR; ESRA; Era; NR3A1; major ORF; ...
https://www.genwaybio.com/all_polyclonal_antibodies.php?fl=E...

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HPA000449 Anti ESR1 antibody produced in rabbit Ab1, Prestige ...
HPA000449 Anti-ESR1 antibody produced in rabbit Ab1, Prestige Antibodies™ Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous
glycerol ...
http://www.sigmaaldrich.com/catalog/search/ProductDetail/SIG...

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ERα (H-184) Antibody sc-7207
Accession #, OMIM™ Number. Human, ESR1, 2099, 6q25.1, NM_000125 · P03372 · 608446. Mouse, Esr1, 13982, 10 A1, P19785, N/A. Mouse, Esr1, 13982, 10 A1,
P19785 ...
http://www.scbt.com/datasheet-7207-eralpha-h-184-antibody.ht...

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Esr1 estrogen receptor 1 (alpha)
Esr1; AA420328; AU041214; ER-ALPHA; ERA; ERALPHA; ER[A; ESR; ESR1; ESTR; ESTRA; NR3A1. Other Designations. estrogen receptor alpha. Refseq ID(s) ...
http://www.sigmaaldrich.com/catalog/search/SIRNASearchGeneDe...

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A630025C20RIK antibody, A630025C20RIK Antibody, Rabbit IgG ...
Repressor of ligand-dependent transcription activation by ESR1, ESR2, NR3C1, PGR , ... Subunit: Interacts with ESR1 and ESR2 in the presence of estradiol. ...
http://www.genwaybio.com/product_info.php?products_id=44018...

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Esr1 estrogen receptor 1
Properties. Official Symbol. Esr1. Species. Rattus norvegicus. Entrez Gene ID. 24890. Alternate Symbol. Esr1; ER-ALPHA; ESR; ESR1; RNESTROR. Refseq ID(s) ...
http://www.sigmaaldrich.com/catalog/search/SIRNASearchGeneDe...

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Estrogen Receptor alpha antibody [33] (ab2746) reviews | Abcam
The figure clearly shows the nuclear localization of ESR1 in CHO K1 cells expressing human ESR1. The second picture shows a DAPI nuclear stain of the same
...
http://www.abcam.com/index.html?pageconfig=reviews&intAbID=2...

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E
HPA000449, Anti-ESR1 antibody produced in rabbit, affinity isolated antibody, human ... ESR1(2099), human, IHC (p), PA ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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Ywhah antibody, 14-3-3 protein eta Antibody, Rabbit IgG Polyclonal ...
Interacts with many nuclear hormone receptors and cofactors including AR, ESR1, ESR2, MC2R, NR3C1, NRIP1, PPARBP and THRA (By similarity). ...
http://www.genwaybio.com/product_info.php?products_id=20011...

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