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ESR1


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Symbol:ESR1
Name(s):estrogen receptor 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:DKFZp686N23123, ER, ESR, ESRA, Era, NR3A1
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18097104 The ligand-binding domain is produced in Escherichia coli as a cleavable thioredoxin (Trx) fusion in order to improve solubility and the structure determined.
18202578 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18271972 Observational study of gene-disease association. (HuGE Navigator)
18285546 Observational study of gene-disease association. (HuGE Navigator)
18294052 Observational study of gene-disease association. (HuGE Navigator)
18301357 Observational study of gene-disease association. (HuGE Navigator)
18305958 Observational study of gene-disease association. (HuGE Navigator)
18309176 Observational study of gene-disease association. (HuGE Navigator)
18342444 Observational study of gene-disease association. (HuGE Navigator)
18350145 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDHomo sapiens chromosome 22estrogen receptor alpha isoform 1ER interacts with AP1B1.-Pubmed
HPRDaryl hydrocarbon receptorestrogen receptor 1--Pubmed
HPRDaryl hydrocarbon receptorestrogen receptor 1--Pubmed
HPRDAndrogen receptorestrogen receptor 1--Pubmed
HPRDandrogen receptor isoform 1Estrogen receptor alpha--Pubmed
HPRDandrogen receptor isoform 1Estrogen receptor, alpha--Pubmed
HPRDBCL2-associated athanogene isoform 1Lestrogen receptor 1--Pubmed
HPRDBCL2-associated athanogene isoform 1Lestrogen receptor 1--Pubmed
HPRDCyclin D1estrogen receptor 1--Pubmed
BINDHomo sapiens chromosome 11, reference assembly.estrogen receptor 1ER-alpha interacts with cyclin D1 promoter.-Pubmed

Recent Publications on ESR1:

Pubmed Logo
Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture.
BACKGROUND: Osteoporosis is a highly heritable trait. Many candidate genes...
3rd November, 2009
McGill University, Montreal, Quebec, Canada. Ann Intern Med. 2009 Oct 20;151(8):528-37.
Evaluation of in vitro fertilization parameters and estrogen receptor alpha gene polymorphisms for women with unexplained infertility.
PURPOSE: Association of ESR1 gene PvuII, XbaI and (TA)n microsatellite...
30th October, 2009
Department of Medical Biology and Genetics, Faculty of Medicine, Gazi J Assist Reprod Genet. 2009 Oct 29.
DOI Direct Link
Estrogen Receptor ESR1 Is Indispensable for the Induction of Persistent Vaginal Change by Neonatal 5alpha-Dihydrotestosterone Exposure in Mice.
Development of the reproductive organs can be strongly affected by the...
30th October, 2009
Biol Reprod. 2009 Oct 28.
DOI Direct Link
DNA Hypermethylation of ESR1 and PGR in Breast Cancer: Pathologic and Epidemiologic Associations.
Improved understanding of the etiology of estrogen receptor-alpha...
29th October, 2009
1Department of Epidemiology and Population Health, Albert Einstein College Cancer Epidemiol Biomarkers Prev. 2009 Oct 27.
DOI Direct Link
Estrogen receptor {alpha} gene polymorphisms in patients with idiopathic premature ovarian failure.
BACKGROUND It has been reported that polymorphisms in the estrogen...
29th October, 2009
Department of Obstetrics and Gynecology, Dongguk University Ilsan Hum Reprod. 2009 Oct 27.
DOI Direct Link

View more research publications.

Press Releases on ESR1:

BioPortfolio Logo
Interleukin Genetics Reports Third Quarter 2009 Financial Results 12th November, 2009 Interleukin Genetics, Inc.

WALTHAM, Mass., Nov. 12 /PRNewswire-FirstCall/ -- Interleukin Genetics, Inc. (NYSE Amex: ILI) today announced financial and operational results for the third quarter ended September 30,

Interleukin Genetics to Present Research Findings at Upcoming Medical Meetings 13th October, 2009 Interleukin Genetics, Inc.

WALTHAM, Mass., Oct. 13 /PRNewswire-FirstCall/ -- Interleukin Genetics, Inc. (NYSE Amex: ILI) announced today it will present new genetic findings in the fields of

BioNews Results for ESR1

: RSS Logo
BioPortfolio Logo
Interleukin Genetics Inc. (ILGN) to Present Research Findings at Upcoming Medical Meetings
BioSpace:  Oct 14 2009 12:08AM Matching: esr1
Interleukin Genetics to Present Research Findings at Upcoming Medical Meetings
PR Newswire:  Oct 13 2009 3:43PM Matching: esr1
Interleukin Genetics to present new genetic findings on obesity and osteoporosis
News-Medical.Net:  Oct 13 2009 12:08PM Matching: esr1
Interleukin Genetics to Present Research Findings at Upcoming Medical Meetings
Street Insider:  Oct 13 2009 11:49AM Matching: esr1
Interleukin Genetics to Present Research Findings at Upcoming Medical Meetings
Wichita Business Journal:  Oct 13 2009 11:33AM Matching: esr1
Promote your company here: BioNewsCast - Press Release Distribution

View more news.

Clinical Trials:

Clinical Trials Logo
Fulvestrant (FASLODEX™) as a Treatment in Postmenopausal Women With Estrogen Receptor Positive Breast Cancer

Patents:

Patents logo
US Patent No.Title
6812378 Esr1--a plant gene that can promote plant regeneration and transformation
7112404 Process for high throughput DNA methylation analysis
7118853 Methods of classifying, diagnosing, stratifying and treating cancer patients and their tumors
7125658 Small protein that interacts with a ribonucleotide reductase subunit and uses thereof
7125660 Nucleic acid sensor molecules and methods of using same

View more patents.

ESR1 results (if any) from reagent suppliers

Google CSE Logo
ESR1 peptide, Estrogen Receptor-alpha (Ab-106) Antibody Blocking ...
Buy quality ESR1 peptide (n/a), ESR1, Estrogen Receptor-alpha (Ab-106) Antibody Blocking Peptide peptide, (n/an/a). ER; Estradiol receptor; ER-alpha; ...
http://www.genwaybio.com/product_info.php?products_id=213281...

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Antibodies to Steroid Hormones and Related Products
ESR1(2099), human, ARR, WB, pricing. E0521, Anti-Estrogen Receptor (18-32) antibody produced in ... human ... ESR1(2099), human, ELISA (i), IP, WB, pricing
...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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ER alpha antibody, ER alpha Antibody, Mouse Polyclonal Antibody
Mouse polyclonal antiserum to estrogen receptor alpha; 2099; ESR1; 133430; P03372; DKFZp686N23123; ER; ESR; ESRA; Era; NR3A1; major ORF; ...
http://www.genwaybio.com/product_info.php?products_id=198041...

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ERα (C-311) Antibody sc-787
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, ESR1, 2099, 6q25.1, NM_000125 ...
http://www.scbt.com/datasheet-787-eralpha-c-311-antibody.htm...

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CKOZFN1163 CompoZr™ Knockout ZFN Kit human ESR1 (NM_000125)
CKOZFN1163 CompoZr Knockout ZFN Kit human ESR1 (NM_000125) CompoZr Knockout ZFNs create targeted double strand breaks at a gene specific target locus.
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...

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Estrogen Receptor alpha antibody [33] (ab2746) reviews | Abcam
The figure clearly shows the nuclear localization of ESR1 in CHO K1 cells expressing human ESR1. The second picture shows a DAPI nuclear stain of the same
...
http://www.abcam.com/index.html?pageconfig=reviews&intAbID=2...

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MUC1 antibody, MUC1 [B415 (VU13F11)] antibody Antibody, Mouse ...
Interacts with estrogen receptor alpha/ESR1, through its DNA-binding domain, and stimulates its transcription activity. Binds ADAM17. ...
http://www.genwaybio.com/product_info.php?products_id=192917...

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