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ETV5


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Gene DB Home
Symbol:ETV5
Name(s):ets variant gene 5 (ets-related molecule)
Type:protein-coding
Organism:Homo sapiens
Synonyms:ERM
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18172298 A TMPRSS2:ETV5 gene fusion was identified in prostate cancer.
15652352 CD44-mediated hyaluronan binding in myeloid cells is regulated by phosphorylated ERM and the actin cytoskeleton.
15534105 ERM has a role in progression of breast cancer
16615918 analysis of NHERF recognition by ERM proteins
15857832 ERM is subject to SUMO modification and this post-translational modification causes inhibition of transcription-enhancing activity
15620692 The erm gene expression is regulated by the conventional PKC (cPKC) pathway.
12387735 functional role for the ERMs (ezrin/radixin/moesin) as adaptor molecules in the interactions of adhesion receptors and intracellular tyrosine kinases
16613858 Erm is involved in SP-C regulation, which results from an interaction with TTF-1
17489097 Testing various shorter fragments of ERM as bait indicated that the region essential for binding CHD3/ZFH is within the amino acid region 96-349, which contains the central inhibitory DNA-binding domain (CIDD) of ERM
17638886 ERM/ETV5 up-regulation activates MMP-2 and thus has a role during myometrial infiltration in endometrial cancer

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDandrogen receptor isoform 1ets variant gene 5--Pubmed

Recent Publications on ETV5:

Pubmed Logo
Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population.
There is evidence that the obesity phenotype in the Caucasian populations...
24th October, 2009
Laboratory for Endocrinology and Metabolism, Center for Genomic Medicine, J Hum Genet. 2009 Oct 23.
DOI Direct Link
Identification of glial cell line-derived neurotrophic factor-regulated genes important for spermatogonial stem cell self-renewal in the rat.
Spermatogonial stem cells (SSCs) provide the foundation for...
23rd September, 2009
Department of Animal Biology, School of Veterinary Medicine, University of Biol Reprod. 2009 Jul;81(1):56-66. Epub 2009 Apr 1.
DOI Direct Link
Deletion of Frs2alpha from the ureteric epithelium causes renal hypoplasia.
Fibroblast growth factor receptor 2 (Fgfr2) signaling is critical in...
11th September, 2009
Rangos Research Center, Children's Hospital of Pittsburgh of UPMC, Am J Physiol Renal Physiol. 2009 Nov;297(5):F1208-19. Epub 2009 Sep 9.
DOI Direct Link
Age-related changes in lck-Vav signaling pathways in mouse CD4 T cells.
Activation of lck-fyn kinases during T cell receptor signaling leads to...
9th September, 2009
Department of Pathology, University of Michigan School of Medicine, Ann Cell Immunol. 2009;259(1):100-4. Epub 2009 Jun 6.
DOI Direct Link
Proteomic approach to ETV5 during endometrial carcinoma invasion reveals a link to oxidative stress.
Endometrial cancer, the most common gynecological malignancy in western...
2nd September, 2009
Biomedical Research Unit, Research Institute, Vall d'Hebron University Carcinogenesis. 2009 Aug;30(8):1288-97. Epub 2009 May 14.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7588771 Microorganisms for therapy
7588767 Microorganisms for therapy
7547687 Therapeutic treatment methods
7482334 Therapeutic treatment methods
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector

View more patents.

ETV5 results (if any) from reagent suppliers

Google CSE Logo
ERM / Etv5 antibody (ab54704) | Abcam
Mouse monoclonal to ERM / Etv5. ERM is expressed in Sertoli cells and spermatogonial stem cells (SSCs). Studies on knockout mice have shown that it is
...
http://www.abcam.com/ERM-Etv5-antibody-ab54704.html...

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ERM (H-100) Antibody sc-22807
Up-regulation of ERM/ETV5 correlates with the degree of myometrial infiltration in endometrioid endometrial carcinoma. J Pathol. 207: 422-429. ...
http://www.scbt.com/datasheet-22807-erm-h-100-antibody.html...

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ERM / Etv5 antibodies: Stem Cells > Cancer Stem Cells ...
ERM / Etv5 antibodies. ... ERM / Etv5 antibody. WB. Images. Mouse monoclonal. Reacts with: Hu. ab75170 · ERM / Etv5 antibody. WB, ELISA ...
http://www.abcam.com/index.html?t=200883&pt=1&c=4585&ei=&mu=...

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7
Monoclonal Anti-ETV5 antibody produced in mouse clone 7C10, purified immunoglobulin, buffered aqueous solution, 7C10 (monoclonal), mouse, rat, human
...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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ERM (H-06) Antibody sc-100941
Ratón, Etv5, 104156, 16 B1, Q9CXC9, No Aplicable. Ratón, Etv5, 104156, 16 B1, Q9CXC9, No Aplicable. Información sobre pedidos ...
http://www.scbt.com/es/datasheet-100941-erm-h-06-antibody.ht...

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Abcam antibodies and reagents product map
Ankrd26 antibodies (2) · Breast carcinoma amplified sequence 3 antibodies (4) · ERM / Etv5 antibodies (3) · IEX1 antibodies (1) · PAR6 antibodies (5) ...
http://www.abcam.com/index.html?pageconfig=productmap&cl=342...

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