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F10


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Symbol:F10
Name(s):coagulation factor X
Type:protein-coding
Organism:Homo sapiens
Synonyms:FX, FXA
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18245654 Factor XDebrecen: Gly204Arg mutation in factor X causes the synthesis of a non-secretable protein and severe factor X deficiency
18062812 Several strong FXa-binding snake venom group IIA secreted phospholipases A2 that disrupt the function of the coagulation cascade by interacting with FXa by the non-catalytic PL-independent mechanism, were identified.
16580898 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18267072 Study shows that FX binds to the Adenovirus 5 hexon, not fiber, via an interaction between the FX Gla domain and hypervariable regions of the hexon surface.
17973648 Possible locations of prothrombin binding to prothrombinase are indicated by simulation of the docked complex
18000611 maximal thrombin generation in plasma requires membranes with a density of 10-20 mol% PS; thrombin formed in situ induces externalization of PS to approx 10 mol% in a substantial platelet subpopulation.
17726015 Role of the alpha-helix 163-170 in FXA catalytic activity is reported.
17635109 The epidermal growth factor domain 1 of activated factor X (fXa) plays a spacer function in holding the active site of fXa above the membrane surface.
17646160 peptide VP311-325 represents both an Activated protein C and fXa binding region in fVa.
17588602 The crystal structure of NAP5 bound at the active site of gamma-carboxyglutamic acid domainless factor Xa (des-fXa) has been determined at 3.1 A resolution.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDCoagulation Factor 3coagulation factor X preproprotein--Pubmed
HPRDcoagulation factor III precursorCoagulation factor X--Pubmed
HPRDCoagulation factor Vcoagulation factor X preproprotein--Pubmed
HPRDcoagulation factor V precursorCoagulation factor X--Pubmed
HPRDCoagulation factor VIIcoagulation factor X preproprotein--Pubmed
HPRDcoagulation factor VII isoform a precursorCoagulation factor X--Pubmed
HPRDCoagulation factor VIIIcoagulation factor X preproprotein--Pubmed
HPRDcoagulation factor VIII isoform a precursorCoagulation factor X--Pubmed
HPRDCoagulation factor Xserine proteinase inhibitor, clade A, member 5--Pubmed
HPRDCoagulation factor Xplasminogen activator, tissue type isoform 1 preproprotein--Pubmed

Recent Publications on F10:

Pubmed Logo
Vetiver grass, Vetiveria zizanioides: a choice plant for phytoremediation of heavy metals and organic wastes.
Glasshouse and field studies showed that Vetiver grass can produce high...
29th October, 2009
Chemical Sciences Building (F10), School of Chemical Sciences and Int J Phytoremediation. 2009 Oct-Dec;11(8):664-91.
Nanowire Biocompatibility in the Brain - Looking for a Needle in a 3D Stack.
We investigated the brain-tissue response to nanowire implantations in the...
23rd October, 2009
Neuronano Research Center, BMC F10, Lund University, SE-221 84 Lund, Nano Lett. 2009 Oct 21.
DOI Direct Link
The highly attenuated oncolytic recombinant vaccinia virus GLV-1h68: comparative genomic features and the contribution of F14.5L inactivation.
As a new anticancer treatment option, vaccinia virus (VACV) has shown...
21st October, 2009
Genelux Corporation, San Diego Science Center, 3030 Bunker Hill St., Ste. Mol Genet Genomics. 2009 Oct;282(4):417-35. Epub 2009 Aug 22.
DOI Direct Link
Long-term outcome of in-patients with substance use disorders: A study from North India.
BACKGROUND: Research into substance use disorders (SUD) has been unable to...
14th October, 2009
Department of Psychiatry, Postgraduate Institute of Medical Education and Indian J Psychiatry. 2008 Oct;50(4):269-73.
DOI Direct Link
Development of physiological resistance and its stage specificity in Culex quinquefasciatus after selection with deltamethrin in Assam, India.
The study investigated the development and stage specificity of...
13th October, 2009
Medical Entomology Division, Defence Research Laboratory, Tezpur, Assam, Mem Inst Oswaldo Cruz. 2009 Aug;104(5):673-7.

View more research publications.

Press Releases on F10:

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Reportlinker Adds Prefeasibility Report - Specaility and Multi- Speciality Hospitals (2009) 26th October, 2009 Reportlinker

NEW YORK, Oct. 26 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue.

Oncolytics Biotech(R) Inc. Collaborators Present Reovirus Research at Replicating Oncolytic Virus Meeting

23rd March, 2009 Oncolytics Biotech Inc.

CALGARY, March 23 /PRNewswire-FirstCall/ - Oncolytics Biotech Inc. (TSX: ONC, NASDAQ: ONCY) announced results of two preclinical studies that were presented at the Fifth International Meeting on

Oncolytics Biotech Inc. Collaborators to Present Preclinical Combination REOLYSIN(R) and Cisplatin Research at EORTC-NCI-AACR Annual Meeting 22nd October, 2008 Oncolytics Biotech Inc.

CALGARY, Oct. 22 /PRNewswire-FirstCall/ - Oncolytics Biotech Inc. (TSX: ONC, NASDAQ: ONCY) announced today that a poster presentation authored by Prof. Hardev Pandha of The Royal Surrey Hospital, U

Effect of CytoregR on Biomarkers in B16-F10 Murine Melanoma 1st January, 1970 Cytorex Biosciences

Effect of CytoregR on Biomarkers in B16-F10 Murine Melanoma

BioNews Results for F10

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XOMA to Develop Therapeutic Antibody for H1N1 and H5N1 Influenza Viruses Under $2.2 Million U.S. Government Pr
Stockwatch:  Sep 23 2009 7:03PM Matching: f10

Clinical Trials:

Clinical Trials Logo
A Study Investigating Treatment Factor X in People With Factor X Deficiency

Patents:

Patents logo
US Patent No.Title
7585953 Antibodies specific for TAT285-1
7595045 Anti-.alpha.9 integrin antibody and the use thereof
7595046 Treatment of cancer using anti-Apo-2 antibodies
7595159 Prediction of Parkinson's disease using gene expression levels of peripheral blood samples
7595350 Ultraporous sol gel monoliths

View more patents.

F10 results (if any) from reagent suppliers

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CD44 antibody [F10-44-2] (ab6124) | Abcam
Mouse monoclonal [F10-44-2] to CD44. CD44 is a type 1 transmembrane glycoprotein also known as Phagocytic Glycoprotein 1 (pgp 1) and HCAM.
http://www.abcam.com/CD44-antibody-F10-44-2-ab6124.html...

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CD45 (F10-89-4) Antibody sc-52490
CD45 (F10-89-4) FITC, sc-52490 FITC, 100 tests in 2 ml ... CD45 (F10-89-4): sc- 52490. Western blot analysis of CD45 expression in human PBL whole cell ...
http://www.scbt.com/datasheet-52490-cd45-f10-89-4-antibody.h...

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Factor X antibody [F10-1] (ab19096) | Abcam
Mouse monoclonal [F10-1] to Factor X. Factor X is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor ...
http://www.abcam.com/Factor-X-antibody-F10-1-ab19096.html...

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HCAM (F10-44-2) Antibody sc-52535
Indirect FCM analysis of human peripheral blood leukocytes stained with HCAM ( F10-44-2), followed by PE-conjugated goat anti-mouse IgG2a: sc-3765. ...
http://www.scbt.com/datasheet-52535-hcam-f10-44-2-antibody.h...

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CD45 antibody [F10-89-4] (Biotin) (ab30468) | Abcam
Mouse monoclonal [F10-89-4] to CD45 (Biotin). CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms (220, ...
http://www.abcam.com/cd45-antibody-f10-89-4-biotin-ab30468.h...

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Factor X (F10-1) Antibody sc-69654
Factor X (F10-1) Antibody sc-69654 Factor X (F10-1) Antibody sc-69654.
http://www.scbt.com/datasheet-69654-factor-x-f10-1-antibody....

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human CD182 antibody, Phycoerythrin (PE) conjugate
The eBio5E8-C7-F10 monoclonal antibody reacts with human CD182 (CXCR2, IL-8Rβ). ... This eBio5E8-C7-F10 (5E8-C7-F10) antibody has been reported for use in ...
http://www.ebioscience.com/ebioscience/specs/antibody_12/12-...

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