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F10
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18245654 |
Factor XDebrecen: Gly204Arg mutation in factor X causes the synthesis of a non-secretable protein and severe factor X deficiency |
| 18062812 |
Several strong FXa-binding snake venom group IIA secreted phospholipases A2 that disrupt the function of the coagulation cascade by interacting with FXa by the non-catalytic PL-independent mechanism, were identified. |
| 16580898 |
Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) |
| 18267072 |
Study shows that FX binds to the Adenovirus 5 hexon, not fiber, via an interaction between the FX Gla domain and hypervariable regions of the hexon surface. |
| 17973648 |
Possible locations of prothrombin binding to prothrombinase are indicated by simulation of the docked complex |
| 18000611 |
maximal thrombin generation in plasma requires membranes with a density of 10-20 mol% PS; thrombin formed in situ induces externalization of PS to approx 10 mol% in a substantial platelet subpopulation. |
| 17726015 |
Role of the alpha-helix 163-170 in FXA catalytic activity is reported. |
| 17635109 |
The epidermal growth factor domain 1 of activated factor X (fXa) plays a spacer function in holding the active site of fXa above the membrane surface. |
| 17646160 |
peptide VP311-325 represents both an Activated protein C and fXa binding region in fVa. |
| 17588602 |
The crystal structure of NAP5 bound at the active site of gamma-carboxyglutamic acid domainless factor Xa (des-fXa) has been determined at 3.1 A resolution. | →View more information from publications. |
Recent Publications on F10: |  |
Lowering bone mineral affinity of bisphosphonates as a therapeutic strategy to optimize skeletal tumor growth inhibition in vivo.
Bisphosphonates bind avidly to bone mineral and are potent inhibitors of... | 1st November, 2008
| Faculte de Medecine Laennec, Institut National de la Sante et de la
| Cancer Res. 2008 Nov 1;68(21):8945-53.
DOI Direct Link |
Biochemical mechanism of acetylsalicylic acid (Aspirin) selective toxicity toward melanoma cell lines.
In the current work, we investigated the biochemical toxicity of... | 31st October, 2008
| aDepartment of Pharmaceutical Sciences, School of Pharmacy bDepartment of
| Melanoma Res. 2008 Oct 28.
DOI Direct Link |
Effects of copper ions released from metallic copper on CHO-K1 cells.
The aim of this study was to investigate the cytotoxic and genotoxic... | 28th October, 2008
| INIFTA (Instituto de Investigaciones Fisicoquimicas Teoricas y Aplicadas),
| Mutat Res. 2008 Oct 4.
DOI Direct Link |
Molecular Mapping of the Stb4 Gene for Resistance to Septoria tritici Blotch in Wheat.
ABSTRACT Breeding wheat for resistance is the most effective means to... | 24th October, 2008
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| Phytopathology. 2004 Nov;94(11):1198-1206.
DOI Direct Link |
Immunosurveillance of lung melanoma metastasis in EBI-3-deficient mice mediated by CD8+ T cells.
EBV-induced gene 3 (EBI-3) codes for a soluble type I receptor homologous... | 23rd October, 2008
| Laboratory of Cellular and Molecular Immunology of the Lung, I. Medical
| J Immunol. 2008 Nov 1;181(9):6148-57.
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→View more research publications. |
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