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FABP1


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Symbol:FABP1
Name(s):fatty acid binding protein 1, liver
Type:protein-coding
Organism:Homo sapiens
Synonyms:FABPL, L-FABP
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18094680 Urinary L-FABP levels represent a sensitive and predictive early biomarker of acute kidney injury after cardiac surgery.
15249972 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
15308127 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15547295 Observational study of gene-disease association. (HuGE Navigator)
16945373 Observational study of gene-disease association. (HuGE Navigator)
17485234 Observational study of gene-disease association. (HuGE Navigator)
17698986 Observational study of gene-disease association. (HuGE Navigator)
17605029 Intestinal L-FABP expression was investigated by immuno-histochemistry, western blot, ELISA and Northern blot analysis
17698986 The Ala/Ala(94)-mutation contributed significantly to reduced glycogenolysis and less severe hyperglycemia in lipid-exposed humans and was further associated with reduced body weight in a large cohort.
17826730 Hypoxia enhances the expression of FABP1 in term human trophoblasts, suggesting that fatty acid binding proteins support fat accumulation in the hypoxic placenta.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDFatty acid binding protein 1peroxisome proliferative activated receptor gamma isoform 2--Pubmed
HPRDfatty acid binding protein 1, liverPeroxisome proliferator activated receptor, alpha--Pubmed
HPRDfatty acid binding protein 1, liverPeroxisome proliferator activated receptor, gamma--Pubmed

Recent Publications on FABP1:

Pubmed Logo
Urinary fatty acids and liver-type fatty acid binding protein in diabetic nephropathy.
BACKGROUND: The aims of this clinical study were to investigate the...
11th September, 2009
Department of Nephrology and Hypertension, Internal Medicine, St. Marianna Nephron Clin Pract. 2009;112(3):c148-56. Epub 2009 Apr 24.
DOI Direct Link
L-FABP directly interacts with PPARalpha in cultured primary hepatocytes.
Although studies with liver type fatty acid binding protein (L-FABP) gene...
2nd September, 2009
Department of Physiology and Pharmacology, Texas A&M University, College J Lipid Res. 2009 Aug;50(8):1663-75. Epub 2009 Mar 16.
DOI Direct Link
Comparative analysis of gene regulation by the transcription factor PPARalpha between mouse and human.
BACKGROUND: Studies in mice have shown that PPARalpha is an important...
28th August, 2009
Nutrigenomics Consortium, Top Institute (TI) Food and Nutrition, PLoS One. 2009 Aug 27;4(8):e6796.
DOI Direct Link
Differential proteomic analysis of STAT6 knockout mice reveals new regulatory function in liver lipid homeostasis.
Increased inflammatory signaling is a key feature of metabolic disorders....
12th August, 2009
Department of Cellular Physiology and Metabolism, University of Geneva, J Proteome Res. 2009 Oct;8(10):4511-24.
DOI Direct Link
Effect of red wine on urinary protein, 8-hydroxydeoxyguanosine, and liver-type fatty acid-binding protein excretion in patients with diabetic nephropathy.
The aim of the present study was to determine whether red or white wine...
12th August, 2009
Department of Medicine, Shinmatsudo Central General Hospital, Chiba, Metabolism. 2009 Aug;58(8):1185-90. Epub 2009 Jun 18.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7588771 Microorganisms for therapy
6905827 Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
7026121 Methods and compositions for diagnosing and monitoring transplant rejection
7119249 Methods and transgenic mouse model for identifying and modulating factors involved in the production of reactive oxygen intermediates
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector

View more patents.

FABP1 results (if any) from reagent suppliers

Google CSE Logo
Rat FABP1 MAb (Clone 220119)
This antibody was selected for its ability to detect rat FABP1 in direct ... secondary reagents to detect rat FABP1. The detection limit for rrFABP1 is ...
http://www.rndsystems.com/pdf/mab1565.pdf...

Thumbshot
POLYCLONAL ANTIBODY TO HUMAN LIVER FATTY ACID BINDING PROTEIN (L ...
The L-FABP protein is derived from the human FABP1 gene. FABPs are small ... in the epithelium of the proximal tubule of the kidney. Aliases. FABP1. Species ...
http://www.hbt.nl/HP9021.pdf...

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Cayman Chemical | FABP1 (human recombinant) | Description • Fatty ...
Source: recombinant N-terminal hexahistidine-tagged protein expressed in E. coli · Mr: 18.3 kDa · Fatty acid binding protein 1 (FABP1) is one of nine known ...
http://www.caymanchem.com/app/template/Product.vm/catalog/10...

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MONOCLONAL ANTIBODY TO HUMAN LIVER FATTY ACID BINDING PROTEIN (L ...
The L-FABP protein is derived from the human FABP1 gene. FABPs ... FABP1. Species. Mouse IgG1. Cross reactant. Reactivity. Cross reactivity. Human H-FABP
...
http://www.hbt.nl/HM2051.pdf...

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Cayman Chemical | FABP1 (rat recombinant) | Description • Fatty ...
1 FABP1 is composed of ten antiparallel β strands that form a barrel with a bigger binding pocket than the other FABPs allowing it to accommodate two fatty
...
http://www.caymanchem.com/app/template/Product.vm/catalog/10...

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POLYCLONAL ANTIBODY TO RAT LIVER FATTY ACID BINDING PROTEIN (L ...
The L-FABP protein is derived from the rat FABP1 gene. FABPs are small ... FABP1 . Species. Rabbit IgG. Cross reactant. Reactivity. Cross reactivity ...
http://www.hbt.nl/HP8010.pdf...

Thumbshot
FABP1/L-FABP - R&D Systems
FABP1/L-FABP. Fatty acid binding proteins are small cytoplasmic lipid binding proteins that are expressed in a tissue specific manner. ...
http://www.rndsystems.com/molecule_detail.aspx?m=1413...

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