BioPortfolio - FABP7 - fatty acid binding protein 7, brain

FABP7

Symbol:

FABP7

Name(s):

fatty acid binding protein 7, brain

Type:

protein-coding

Organism:

Homo sapiens

Synonyms:

B-FABP, BLBP, DKFZp547J2313, FABPB, MRG

Links:

Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link

Summary of findings

17898869

B-FABP expression in malignant glioma cells is accompanied by the appearance of radial glial-like properties, as well as reduced transformation. B-FABP depletion results in decreased migration, reduction in cell processes, & a more transformed phenotype.

17415524

relation between FABP7, astrocytic features, invasion and poor prognosis and suggests that EGFR amplification is associated with nuclear translocation of FABP7.

12612091

BLBP, stimulated by Ras-independent pathways, regulates Schwann cell-axon interactions in normal peripheral nerve and peripheral nerve tumors.

12975368

data indicate that MRG is a mediator of the differentiating effects of pregnancy on breast epithelium

16623952

A possible mechanism for the association of nuclear FABP7 & poor prognosis of glioblastoma multiforme is that nuclear FABP7 may be induced by EGFR activation to promote migration of GBM tumor cells.

12771203

Overexpression of FABP7 in Down syndrome fetal brains.

12479569

overall structure exhibits the typical backbone conformation described for other members of the FABP family, consisting of antiparallel beta-strands that form two almost orthogonal beta-sheets, a helix-turn-helix motif and a short N-terminal helical loop

15827123

Increases tumor cell motility in vitro and over-expression is associated with poor prognosis in glioblastoma patients

12975368

Functional analysis in mice.