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FANCE
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17296736 |
Chk1-mediated phosphorylation of FANCE is required for a function independent of FANCD2 monoubiquitination. |
| 12239156 |
This Fanconi anemia protein promotes the nuclear accumulation of FANCC. |
| 17308347 |
Disease-associated mutations disrupt the FANCE-FANCD2 interaction, providing structural insight into the molecular mechanisms of Fanconi Anaemia pathogenesis. |
| 12093742 |
FANCE protein is part of the FA nuclear complex, binding FANCC & FANCD2. It is required for the nuclear accumulation of FANCC and provides a bridge between the FA complex and FANCD2. FANCC mutants do not bind FANCE or prevent chromosome breakage. |
| 16127171 |
FANCC, FANCE, and FANCD2 form a ternary complex in the Fanconi anemia DNA damage response pathway |
| 16513431 |
nuclear accumulation of FANCE does not rely solely on its nuclear localization signal motifs, but also on FANCC |
Interacting gene products |
| Interaction Type |
Gene 1 |
Gene 2 |
Interaction description |
Complex |
Publication Link |
| HPRD | Fanconi anemia, complementation group A | Fanconi anemia, complementation group E | - | - | Pubmed |
| HPRD | Fanconi anemia, complementation group A | Fanconi anemia protein E | - | - | Pubmed |
| HPRD | Fanconi anemia, complementation group C | Fanconi anemia, complementation group E | - | - | Pubmed |
| HPRD | Fanconi anemia, complementation group C | Fanconi anemia protein E | - | - | Pubmed |
| HPRD | Fanconi anemia, complementation group D2 | Fanconi anemia, complementation group E | - | - | Pubmed |
| HPRD | Fanconi anemia complementation group D2 isoform a | Fanconi anemia protein E | - | - | Pubmed |
| HPRD | Fanconi anemia protein E | Fanconi anemia, complementation group G | - | - | Pubmed |
| HPRD | Fanconi anemia, complementation group E | Fanconi anemia group G protein | - | - | Pubmed |
Recent Publications on FANCE: |  |
Fanconi Anemia Complementation Group FANCD2 Protein Serine 331 Phosphorylation Is Important for Fanconi Anemia Pathway Function and BRCA2 Interaction.
Fanconi anemia is a cancer-prone inherited bone marrow failure and cancer... | 29th October, 2009
| Department of Microbiology, University of Virginia Health System,
| Cancer Res. 2009 Oct 27.
DOI Direct Link |
Protection against hepatocyte mitochondrial dysfunction delays fibrosis progression in mice.
Accumulating evidence indicates that oxidative stress is involved in the... | 8th October, 2009
| Institut Cochin, Universite Paris Descartes, Centre National de la
| Am J Pathol. 2009 Nov;175(5):1929-37. Epub 2009 Oct 1.
DOI Direct Link |
Identification and characterization of mutations in FANCL gene: a second case of Fanconi anemia belonging to FA-L complementation group.
Fanconi anemia (FA) is a rare autosomal recessive or X-linked disorder... | 24th September, 2009
| Experimental Hematology and Cancer Biology, Cincinnati Children's Research
| Hum Mutat. 2009 Jul;30(7):E761-70.
DOI Direct Link |
A possible approach for stem cell gene therapy of Fanconi anemia.
Fanconi anemia (FA) is an inherited chromosomal recessive syndrome... | 29th April, 2009
| Department of Chemistry, University of Waterloo, Waterloo, ON, Canada.
| Curr Gene Ther. 2009 Feb;9(1):26-32.
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FANCM and FAAP24 function in ATR-mediated checkpoint signaling independently of the Fanconi anemia core complex.
The Fanconi anemia (FA) pathway is implicated in DNA repair and cancer... | 1st January, 2009
| DNA Damage Response Laboratory, Cancer Research UK, Clare Hall, EN6 3LD
| Mol Cell. 2008 Nov 7;32(3):313-24.
DOI Direct Link |
→View more research publications. |
FANCE results (if any) from reagent suppliers | 
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FANC Antibody / FANC Antibodies
FANCE (L-21) Antibody, sc-23585, goat IgG, C-terminus (h), WB, IF, ELISA, human. FANCE (2346C5a) Antibody, sc-130638, mouse IgG2b, N/A, WB, IP, human ...
http://www.scbt.com/table-fanc.html...
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Page 1 of 2 e-mail: info@rockland-inc.com Visit our website at ...
BRCA2), FANCD2, FANCE, FANCF, FANCG, and ... Anti-Human FANCE (Rabbit). 200-401- 674. Anti-Human FANCF (Rabbit). 600-401-671. Anti-Human FANCG (Rabbit) ...
http://www.rockland-inc.com/objects/catalog/product/extras/1...
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FANCE siRNA (h) sc-40569
Click here for details. contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: FANCE (h)-PR: sc-40569-PR, 20 µl ...
http://www.scbt.com/ko/datasheet-40569-fance-sirna-h.html...
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CHEK1 antibody, CHK1 checkpoint homolog (S. pombe) (CHEK1 ...
Chk1-mediated phosphorylation of FANCE is required for the Fanconi anemia/BRCA pathway [5] Reinhardt,H.C., Aslanian,A.S., Lees,J.A. and Yaffe,M.B., et al. ...
http://www.genwaybio.com/product_info.php?products_id=60186...
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FANCE (L-21) Antibody sc-23585
FANCE (L-21) Anticuerpo sc-23585 FANCE (L-21) Antibody sc-23585.
http://www.scbt.com/es/datasheet-23585-fance-l-21-antibody.h...
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Certificate of Analysis Product: Affinity Purified Anti-FANCF ...
FANCC, FANCE, FANCF, FANCG,. FANCL/PHF9 and FANCM. The complex is not found in FA patients. .... Affinity Purified Anti-Human FANCE [Rabbit]. #600-401-674 ...
http://www.rockland-inc.com/objects/catalog/product/extras/1...
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FANCE (L-21) Antibody sc-23585
FANCE (L-21) 抗体 sc-23585 FANCE (L-21) Antibody sc-23585.
http://www.scbt.com/ja/datasheet-23585-fance-l-21-antibody.h...
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