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ACSL3


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Symbol:ACSL3
Name(s):acyl-CoA synthetase long-chain family member 3
Type:protein-coding
Organism:Homo sapiens
Synonyms:ACS3, FACL3, PRO2194
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18003621 Small interfering RNA targeting ACSL3 inhibits secretion of hepatitis c virus from human hepatoma-derived cells
17901542 Data suggest that endogenous FATP4 does not function to translocate fatty acids across the plasma membrane, but functions more as a very long-chain acyl-CoA synthetase.
17761945 Oncostatin M directly lowers the plasma triglycerides in hyperlipidemia by stimulating the transcription of ACSL3/5 in the liver.
15556626 Repression of FAS mRNA expression is the consequence of feedback inhibition of FAS expression by long chain fatty acyl-CoAs, which are formed by FACL3 during its upregulation by vitamin D3in prostate cancer cells.
11707336 Sequence analysis of genomic clones demonstrates that the human ACS3 gene spans at least 80.6 kb and contains 17 exons.

Recent Publications on ACSL3:

Pubmed Logo
Hepatic Expression of Long-Chain Acyl-CoA Synthetase 3 is Upregulated in Hyperlipidemic Hamsters.
Members of the mammalian long-chain acyl-CoA synthetase (ACSL) family are...
17th September, 2009
Veterans Affairs Palo Alto Health Care System, 3801 Miranda Avenue, Palo Lipids. 2009 Sep 15.
DOI Direct Link
Suppression of long chain acyl-CoA synthetase 3 decreases hepatic de novo fatty acid synthesis through decreased transcriptional activity.
Long chain acyl-CoA synthetases (ACSL) and fatty acid transport proteins...
10th September, 2009
Department of Food Sciences and Nutrition, University of Minnesota, St J Biol Chem. 2009 Oct 30;284(44):30474-83. Epub 2009 Sep 8.
DOI Direct Link
Analyses of mental dysfunction-related ACSl4 in Drosophila reveal its requirement for Dpp/BMP production and visual wiring in the brain.
Long-chain acyl-CoA synthetases (ACSLs) convert long-chain fatty acids to...
21st July, 2009
Institute of Genetics and Developmental Biology, Chinese Academy of Hum Mol Genet. 2009 Oct 15;18(20):3894-905. Epub 2009 Jul 19.
DOI Direct Link
Relation of DNA methylation of 5'-CpG island of ACSL3 to transplacental exposure to airborne polycyclic aromatic hydrocarbons and childhood asthma.
In a longitudinal cohort of approximately 700 children in New York City,...
2nd April, 2009
The Columbia Center for Children's Environmental Health, Columbia PLoS One. 2009;4(2):e4488. Epub 2009 Feb 16.
DOI Direct Link
Fatty acid transport and activation and the expression patterns of genes involved in fatty acid trafficking.
These studies defined the expression patterns of genes involved in fatty...
27th September, 2008
Center for Metabolic Disease, Ordway Research Institute, 150 New Scotland Arch Biochem Biophys. 2008 Sep 15;477(2):363-71. Epub 2008 Jun 20.
DOI Direct Link

View more research publications.

ACSL3 results (if any) from reagent suppliers

Google CSE Logo
ACSL3 Antibody Fatty-acid-coenzyme A Ligase
ACSL3 antibody can be used for detection of ACSL3 by WB (minimum working concentration: 1 μg/ml maximum working concentration: 1 μg/ml), and ELISA (
minimum ...
http://www.prosci-inc.com/shop/catalog1/ACSL3-Antibody-p-328...

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ACSL3 antibody (ab78229) | Abcam
Rabbit polyclonal to ACSL3. ACSL3 (long-chain fatty-acid-Coenzyme A ligase 3) is an isozyme of the long-chain fatty-acid-coenzyme A ligase family.
http://www.abcam.com/ACSL3-antibody-ab78229.html...

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ACSL3 (FACL3) Antibody (N-term)
Long-chain acyl-CoA synthetase 3, ACSL3, ACS3, LACS3 ... ACSL3 (FACL3) Antibody (N-term). Western blot analysis of anti-FACL3 Antibody (N-term) (Cat. ...
http://www.abgent.com/products/catalog_no/AP2535a_ACSL3_FACL...

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ACSL3 (H-9) Antibody sc-166374
ACSL3 (H-9) Data. Click on image to enlarge. sc-166374. ACSL3 (H-9): sc-166374. Western blot analysis of ACSL3 expression in TE671 whole cell lysate. ...
http://www.scbt.com/datasheet-166374-acsl3-h-9-antibody.html...

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ACSL3 antibodies: Signal Transduction > Metabolism > Lipid ...
ACSL3 antibodies. ... ACSL3 antibody - Aminoterminal end. WB, ELISA. Rabbit polyclonal. Reacts with: Hu. Terms and conditions · Legal · Privacy policy ...
http://www.abcam.com/index.html?t=228077&pt=1&c=3612&ei=&mu=...

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ACSL Antibody / ACSL Antibodies
ACSL3 (H-9) Antibody, sc-166374, mouse IgG2b, 645-672 (h), WB, IP, IF, ELISA, m, r, h. ACSL3 (H-96) Antibody, sc-134497, rabbit IgG, 193-288 (h), WB, IP, ...
http://www.scbt.com/table-acsl.html...

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Neurobiology Antibodies :: Page 1
Acetylcholinesterase Antibody, 48-958, H, WB, IHC, Acetylcholinesterase. ACSL3 Antibody, 48-959, H, E, WB, IHC, Fatty-acid-coenzyme A Ligase ...
http://www.prosci-inc.com/shop/catalog1/Neurobiology-Antibod...

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