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FANCB


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Symbol:FANCB
Name(s):Fanconi anemia, complementation group B
Type:protein-coding
Organism:Homo sapiens
Synonyms:FA2, FAAP90, FAAP95, FAB, FACB
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18302019 Observational study of genotype prevalence. (HuGE Navigator)
17903171 Mus81 and FANCB have different roles in repair of DNA damage during replication in human cells
15502827 the protein defective in individuals with Fanconi anemia belonging to complementation group B is an essential component of the nuclear protein 'core complex' responsible for monoubiquitination of FANCD2
15611632 summary of recent advances in the Fanconi anemia-BRCA network with emphasis on the new discovery of FAAP95 as the true FANCB gene [review]
16679491 Mutations in FANCB are a cause of X linked VACTERL-H syndrome.

Recent Publications on FANCB:

Pubmed Logo
Fanconi Anemia Complementation Group FANCD2 Protein Serine 331 Phosphorylation Is Important for Fanconi Anemia Pathway Function and BRCA2 Interaction.
Fanconi anemia is a cancer-prone inherited bone marrow failure and cancer...
29th October, 2009
Department of Microbiology, University of Virginia Health System, Cancer Res. 2009 Oct 27.
DOI Direct Link
Identification and characterization of mutations in FANCL gene: a second case of Fanconi anemia belonging to FA-L complementation group.
Fanconi anemia (FA) is a rare autosomal recessive or X-linked disorder...
24th September, 2009
Experimental Hematology and Cancer Biology, Cincinnati Children's Research Hum Mutat. 2009 Jul;30(7):E761-70.
DOI Direct Link
A possible approach for stem cell gene therapy of Fanconi anemia.
Fanconi anemia (FA) is an inherited chromosomal recessive syndrome...
29th April, 2009
Department of Chemistry, University of Waterloo, Waterloo, ON, Canada. Curr Gene Ther. 2009 Feb;9(1):26-32.
Analysis of FANCB and FANCN/PALB2 fanconi anemia genes in BRCA1/2-negative Spanish breast cancer families.
Recent reports have shown that mutations in the FANCJ/BRIP1 and...
12th February, 2009
Group of Human Genetics, Human Cancer Genetics Program, Spanish National Breast Cancer Res Treat. 2009 Feb;113(3):545-51. Epub 2008 Feb 27.
DOI Direct Link
Human Mus81 and FANCB independently contribute to repair of DNA damage during replication.
Recent studies suggest a crucial role for homologous recombination (HR) in...
6th December, 2007
Kihara Institute for Biological Research, Graduate School of Integrated Genes Cells. 2007 Oct;12(10):1111-22.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
Study of Mitomycin-C in Patients With Advanced or Recurrent Pancreatic Cancer With Mutated BRCA2 Gene

Patents:

Patents logo
US Patent No.Title
7531530 Therapeutic compounds
7351701 Therapeutic compounds
7291461 Methods for identifying small molecules that modulate premature translation termination and nonsense mRNA decay

FANCB results (if any) from reagent suppliers

Google CSE Logo
FANC Antibody / FANC Antibodies
FANCB (C-13) Anticorpo, sc-131514, goat IgG, C-terminal (h), WB, IF, ELISA, human .... FANCB shRNA Plasmid (m): sc-145062-SH. FANCB shRNA (m) ...
http://www.scbt.com/pt/table-fanc.html...

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Page 1 of 2 e-mail: info@rockland-inc.com Visit our website at ...
complex composed of FANCA, FANCB, FANCC, FANCE,. FANCF, FANCG, FANCL/PHF9 and FANCM. FANCG contains a. 5-prime GC-rich untranslated region characteristic of
...
http://www.rockland-inc.com/objects/catalog/product/extras/1...

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FANCB siRNA (m) sc-145062
Click here for details. suitable control antibody: contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: FANCB ...
http://www.scbt.com/ko/datasheet-145062-fancb-sirna-m.html...

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Page 1 of 2 e-mail: info@rockland-inc.com Visit our website at ...
includes FANCA, FANCB, FANCC, FANCD1 (also called. BRCA2), FANCD2, FANCE, FANCF, FANCG, and. FANCL. The previously defined group FANCH is the same as FANCA. ...
http://www.rockland-inc.com/objects/catalog/product/extras/1...

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Site Map Bethyl Laboratories
FANCB ...
http://www.bethyl.com/content/sitemap...

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Certificate of Analysis Product: Affinity Purified Anti-FANCF ...
composed of FANCA, FANCB,. FANCC, FANCE, FANCF, FANCG,. FANCL/PHF9 and FANCM. The complex is not found in FA patients. FANCF is found within the nucleus. ...
http://www.rockland-inc.com/objects/catalog/product/extras/1...

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Abcam antibodies and reagents product map
BACH1/BRIP1 antibodies (6) · FAAP24 antibodies (1) · FAAP24 proteins and peptides (2) · FANCA antibodies (3) · FANCB antibodies (2) · FANCC antibodies (6
) ...
http://www.abcam.com/index.html?c=250...

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