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FANCB


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Symbol:FANCB
Name(s):Fanconi anemia, complementation group B
Type:protein-coding
Organism:Homo sapiens
Synonyms:FA2, FAAP90, FAAP95, FAB, FACB
Links: Pubmed, Entrez Gene, GeneCards, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18302019 Observational study of genotype prevalence. (HuGE Navigator)
17903171 Mus81 and FANCB have different roles in repair of DNA damage during replication in human cells
15502827 the protein defective in individuals with Fanconi anemia belonging to complementation group B is an essential component of the nuclear protein 'core complex' responsible for monoubiquitination of FANCD2
15611632 summary of recent advances in the Fanconi anemia-BRCA network with emphasis on the new discovery of FAAP95 as the true FANCB gene [review]
16679491 Mutations in FANCB are a cause of X linked VACTERL-H syndrome.

Recent Publications on FANCB:

Pubmed Logo
Analysis of FANCB and FANCN/PALB2 Fanconi Anemia genes in BRCA1/2-negative Spanish breast cancer families.
Recent reports have shown that mutations in the FANCJ/BRIP1 and...
28th February, 2008
Group of Human Genetics, Human Cancer Genetics Program, Spanish National Breast Cancer Res Treat. 2008 Feb 27.
DOI Direct Link
Human Mus81 and FANCB independently contribute to repair of DNA damage during replication.
Recent studies suggest a crucial role for homologous recombination (HR) in...
6th December, 2007
Kihara Institute for Biological Research, Graduate School of Integrated Genes Cells. 2007 Oct;12(10):1111-22.
DOI Direct Link
FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway.
The Fanconi anemia (FA) core complex plays a central role in the DNA...
5th October, 2007
Laboratory of Genetics, National Institute on Aging, National Institutes EMBO J. 2007 Apr 18;26(8):2104-14. Epub 2007 Mar 29.
DOI Direct Link
Downregulation of Fanconi anemia genes in sporadic head and neck squamous cell carcinoma.
BACKGROUND/AIMS: Much of our understanding of human cancer has come from...
27th September, 2007
Department of Otolaryngology - Head and Neck Surgery, University of ORL J Otorhinolaryngol Relat Spec. 2007;69(4):218-25. Epub 2007 Apr 4.
DOI Direct Link
Fanconi anaemia complementation group B presenting as X linked VACTERL with hydrocephalus syndrome.
BACKGROUND: The VACTERL with hydrocephalus (VACTERL-H) phenotype is...
4th January, 2007
Department of Clinical Genetics, 7th Floor New Guy's House, Guy's J Med Genet. 2006 Sep;43(9):750-4. Epub 2006 May 5.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
Study of Mitomycin-C in Patients With Advanced or Recurrent Pancreatic Cancer With Mutated BRCA2 Gene
Pancreatic Cancer

Patents:

Patents logo
US Patent No.Title
7351701 Therapeutic compounds
7291461 Methods for identifying small molecules that modulate premature translation termination and nonsense mRNA decay

FANCB results (if any) from reagent suppliers

Google CSE Logo
HPA003124 Anti FANCB antibody produced in rabbit Prestige ...
HPA003124 Anti-FANCB antibody produced in rabbit Prestige Antibodies™ Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol ...
http://www.sigmaaldrich.com/catalog/search/ProductDetail/SIG...

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Alternative names for BRCA2 (phospho T3349) antibody (ab36459)
... Breast cancer type 2 susceptibility protein antibody; FACD antibody; FAD 1 antibody; FAD antibody; FAD1 antibody; FANCB antibody; FANCD 1 antibody ...
http://www.abcam.com/assets/popups/alternative-names.htm?int...

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F
HPA003124, Anti-FANCB antibody produced in rabbit, affinity isolated antibody, human ... FANCB(2187), human, IHC (p), PA, WB ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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Primary Antibodies - GenWay Biotech Inc.
BRCA2; 675; BRCA2; 114480; P51587; BRCC2; FACD; FAD; FAD1; FANCB; FANCD; FANCD1; - Rabbit polyclonal to BRCA2;, IgG Polyclonal IF, IP, Source: Rabbit ...
https://www.genwaybio.com/all_primary_antibodies.php?fl=B&so...

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BRCA2 Antibody Bethyl Laboratories
BRCA2 is also known as breast cancer type 2 susceptibility protein, Fanconi anemia group D1 protein, FAC, FACD, FAD1, FANCD1, FANCB, and BRCC2 . ...
https://www.bethyl.com/go/?product/A300-005A/TreeKey=4789553...

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FANCE antibody (ab5064) datasheet | Abcam
FANCE (Fanconi Anemia Complementation Group, E) is a component of the nuclear Fanconia Anaemia complex which currently includes FANCA, FANCB, FANCC, ...
http://www.abcam.com/index.html?datasheet=5064...

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WH0000675M1 Monoclonal Anti BRCA2 antibody produced in mouse clone ...
Synonym. Anti-breast cancer 2, early onset. Anti-FACD. Anti-FAD1. Anti-FAD. Anti -FANCB. Anti-FANCD1. Anti-FANCD. Expand/Collapse All. Price and Availability ...
http://www.sigmaaldrich.com/catalog/search/ProductDetail/SIG...

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Certificate of Analysis Product: Affinity Purified Anti-FANCF ...
composed of FANCA, FANCB,. FANCC, FANCE, FANCF, FANCG,. FANCL/PHF9 and FANCM. The. complex is not found in FA patients. FANCF is found within the nucleus. ...
http://www.rockland-inc.com/objects/catalog/product/extras/1...

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BRCA2 breast cancer 2, early onset
BRCA2; BRCC2; FACD; FAD; FAD1; FANCB; FANCD; FANCD1. Other Designations. BRCA1/ BRCA2-containing complex, subunit 2; Fanconi anemia, complementation group D1
...
http://www.sigmaaldrich.com/catalog/search/SIRNASearchGeneDe...

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Sitemap
... promotes the formation of neurite-like membrane extensions · Human Mus81 and FANCB independently contribute to repair of DNA damage during replication ...
http://www.immuquest.com/sitemap.asp...

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