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FANCG
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 16195237 |
Observational study of gene-disease association. (HuGE Navigator) |
| 16609022 |
Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) |
| 12432219 |
Study of the molecular evolution of FA genes using database search methods such as PSI-BLAST suggested that FANCG may contain a known domain, and that this protein is a member of the family of tetratricopeptide repeat-containing proteins. |
| 12649160 |
FANCG was able to mediate interaction between FANCA and FANCF, as well as between monomers of FANCA |
| 12861027 |
FANCG is required for efficient homologous recombination-mediated repair of at least some types of DNA double-strand breaks |
| 15138265 |
FANCA and FANCG uniquely respond to oxidative damage by forming complexes via intermolecular disulfide linkages |
| 15256425 |
FA proteins function at the level of chromatin during S phase to regulate and maintain genomic stability. |
| 16621732 |
FANCG, in addition to stabilising the FA core complex, may have a role in building multiprotein complexes that facilitate homologous recombination repair. |
| 17010390 |
Four human FANCG polymorphic variants show normal biological function. |
| 12552564 |
There is remarkably lage sequence variation in FANCG gene mutations and polymorphisms across ethnic and racial backgrounds found in the International Fanconi Anemia Registry they include IVS8-2A>G, IVS11+1G>c, 1794_1803del10, and IVS3+1G>C. | →View more information from publications. |
Interacting gene products |
| Interaction Type |
Gene 1 |
Gene 2 |
Interaction description |
Complex |
Publication Link |
| BIND | breast cancer 2, early onset | Fanconi anemia, complementation group G | FANCG interacts with BRCA2. | - | Pubmed |
| HPRD | Cytochrome P450, subfamily XIX | Fanconi anemia, complementation group G | - | - | Pubmed |
| HPRD | cytochrome P450, family 19 | Fanconi anemia group G protein | - | - | Pubmed |
| HPRD | Fanconi anemia, complementation group A | Fanconi anemia, complementation group G | - | - | Pubmed |
| HPRD | Fanconi anemia, complementation group A | Fanconi anemia group G protein | - | - | Pubmed |
| BIND | Fanconi anemia, complementation group A | Fanconi anemia, complementation group G | FANCA interacts with FANCG. | - | Pubmed |
| HPRD | Fanconi anemia, complementation group C | Fanconi anemia, complementation group G | - | - | Pubmed |
| HPRD | Fanconi anemia, complementation group C | Fanconi anemia group G protein | - | - | Pubmed |
| HPRD | Fanconi anemia protein E | Fanconi anemia, complementation group G | - | - | Pubmed |
| HPRD | Fanconi anemia, complementation group E | Fanconi anemia group G protein | - | - | Pubmed |
Recent Publications on FANCG: |  |
Fanconi Anemia Complementation Group FANCD2 Protein Serine 331 Phosphorylation Is Important for Fanconi Anemia Pathway Function and BRCA2 Interaction.
Fanconi anemia is a cancer-prone inherited bone marrow failure and cancer... | 29th October, 2009
| Department of Microbiology, University of Virginia Health System,
| Cancer Res. 2009 Oct 27.
DOI Direct Link |
[Construction of FANCA mutant protein from Fanconi anemia patient and analysis of its function]
OBJECTIVE: To study FANCA protein expression in Fanconi anemia patient's... | 6th October, 2009
| Department of Hematology, Zhongnan Hospital of Wuhan University, Wuhan
| Zhonghua Xue Ye Xue Za Zhi. 2007 Nov;28(11):741-4.
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Identification and characterization of mutations in FANCL gene: a second case of Fanconi anemia belonging to FA-L complementation group.
Fanconi anemia (FA) is a rare autosomal recessive or X-linked disorder... | 24th September, 2009
| Experimental Hematology and Cancer Biology, Cincinnati Children's Research
| Hum Mutat. 2009 Jul;30(7):E761-70.
DOI Direct Link |
RAD51D- and FANCG-dependent base substitution mutagenesis at the ATP1A1 locus in mammalian cells.
Elaborate processes act at the DNA replication fork to minimize the... | 25th July, 2009
| Biosciences and Biotechnology Division, L452, Lawrence Livermore National
| Mutat Res. 2009 Jun 1;665(1-2):61-6. Epub 2009 Mar 18.
DOI Direct Link |
Transcriptional changes in U343 MG-a glioblastoma cell line exposed to ionizing radiation.
Glioblastoma multiforme (GBM) is a highly invasive and radioresistant... | 3rd June, 2009
| Department of Genetics, University of Sao Paulo, SP, Brazil.
| Hum Exp Toxicol. 2008 Dec;27(12):919-29.
DOI Direct Link |
→View more research publications. |
FANCG results (if any) from reagent suppliers | 
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