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FGF2


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Symbol:FGF2
Name(s):fibroblast growth factor 2 (basic)
Type:protein-coding
Organism:Homo sapiens
Synonyms:BFGF, FGFB, HBGF-2
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18279437 AT genotype of the 553 T/A polymorphism was associated with PDR in Caucasians with type 2 diabetes.
18279437 Observational study of gene-disease association. (HuGE Navigator)
18042549 the involvement of FGFR-1 through FGF2 in eliciting PGE(2) angiogenic responses
18164591 Support a role for NP-1 in mediating synergistic effects between VEGF-A(165) and FGF-2, which may occur in part through a contribution of NP-1 to KDR stability.
18031768 Developed a mathematical model to numerically simulate angiogenesis induced by basic fibroblast growth factor (bFGF) in the corneal pocket assay.
17706726 Provide useful information for understanding mechanisms of angiogenesis induced by bFGF and important data for validating a mathematical model of angiogenesis.
18006148 IGF-1 and EGF down-regulation and FGF2 up-regulation seem to comprise the main features of endometrial carcinogenesis.
12590983 Observational study of genotype prevalence. (HuGE Navigator)
17204151 Observational study of gene-disease association. (HuGE Navigator)
17653045 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDCD44fibroblast growth factor 2--Pubmed
HPRDCD44 antigenFibroblast growth factor 2--Pubmed
HPRDCD44 antigen isoform 1 precursorFibroblast growth factor 2--Pubmed
HPRDCK2, alpha 1fibroblast growth factor 2--Pubmed
HPRDcasein kinase II alpha 1 subunit isoform aFibroblast growth factor 2--Pubmed
HPRDcasein kinase 2, alpha prime polypeptidefibroblast growth factor 2--Pubmed
HPRDcasein kinase 2, alpha prime polypeptidefibroblast growth factor 2--Pubmed
HPRDGlypican 4fibroblast growth factor 2--Pubmed
HPRDglypican 4Fibroblast growth factor 2--Pubmed
HPRDFibroblast growth factor 2fibroblast growth factor receptor 1 isoform 1 precursor--Pubmed

Recent Publications on FGF2:

Pubmed Logo
Stimulatory effects of thyroid hormone on brain angiogenesis in vivo and in vitro.
Thyroid hormone is critical for the proper development of the central...
29th October, 2009
Center for Brain Repair and Rehabilitation, Institute of Neuroscience and J Cereb Blood Flow Metab. 2009 Oct 28.
DOI Direct Link
Fibroblast growth factor-2 antagonist and antiangiogenic activity of long-pentraxin 3-derived synthetic peptides.
Angiogenesis and inflammation are closely integrated processes. Fibroblast...
29th October, 2009
Unit of General Pathology and Immunology, Department of Biomedical Curr Pharm Des. 2009;15(30):3577-89.
Mutation in the heparan sulfate biosynthesis enzyme Ext1 influences growth factor signaling and fibroblast interaction with the extracellular matrix.
Heparan sulfate (HS) chains bind and modulate the signaling efficiency of...
24th October, 2009
University of Bergen, Norway; J Biol Chem. 2009 Oct 22.
DOI Direct Link
ATP-dependent stabilization and protection of fibroblast growth factor 2.
Fibroblast growth factor 2 (FGF2) plays a pivotal role in cell...
20th October, 2009
Institut fur Pharmazeutische und Medizinische Chemie, Westfalische J Biotechnol. 2009 Oct 15.
DOI Direct Link
Differentiation of human oligodendrocytes from pluripotent stem cells.
We have developed a four-part protocol to differentiate human embryonic...
17th October, 2009
Department of Anatomy and Neurology, School of Medicine and Public Health, Nat Protoc. 2009;4(11):1614-22. Epub 2009 Oct 15.
DOI Direct Link

View more research publications.

BioNews Results for FGF2

: RSS Logo
BioPortfolio Logo
Lonza and ProChon Biotech Strike Manufacturing Deal
Pharma Live:  Nov 9 2009 5:31PM Matching: fgf2
ProChon Biotech Selects Lonza to Locally Manufacture Critical Component of BioCart(TM) Cartilage Regeneration System
Street Insider:  Nov 4 2009 5:16PM Matching: fgf2
ProChon Biotech Selects Lonza to Locally Manufacture Critical Component of BioCart Cartilage Regeneration Syst
Business Wire via Yahoo!:  Nov 4 2009 5:08PM Matching: fgf2
ProChon Biotech Selects Lonza to Locally Manufacture Critical Component of BioCart Cartilage Regeneration System
Business Wire UK:  Nov 4 2009 5:06PM Matching: fgf2
ProChon Biotech Selects Lonza to Locally Manufacture Critical Component of BioCart Cartilage Regeneration Sy
Business Wire:  Nov 4 2009 5:03PM Matching: fgf2
Promote your company here: BioNewsCast - Press Release Distribution

View more news.

Clinical Trials:

Clinical Trials Logo
Trial in Periodontal Tissue Regeneration Using Fibroblast Growth Factor-2

Patents:

Patents logo
US Patent No.Title
7449334 Medium containing pipecholic acid and gamma amino butyric acid and culture of embryonic stem cells
7521048 TRAIL receptor-2 polypeptides and antibodies
7521425 Anti-angiogenic compounds
7524493 Nucleic acid constructs cells transformed therewith and methods utilizing same for inducing liver regeneration and alleviation of portal hypertension
7531354 Neuronal progenitors from feeder-free human embryonic stem cell culture

View more patents.

FGF2 results (if any) from reagent suppliers

Google CSE Logo
FGF2 antibody, FGF2 [FB-8] Antibody, Mouse Monoclonal Antibody
Buy quality mouse FGF2 antibody (interacts with cross-reacts with human and cow. not yet tested in other species.), anti-FGF2, FGF2 [FB-8] antibody, ...
http://www.genwaybio.com/product_info.php?products_id=190207...

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FGF-2 (147) Antibody sc-79
See how others have used FGF-2 (147): sc-79 antibody and or FGF-2 (147) antibody ... Epigenetic Regulation of the Stem Cell Mitogen Fgf-2 by Mbd1 in Adult ...
http://www.scbt.com/datasheet-79-fgf-2-147-antibody.html...

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FGF2 antibody, bFGF Antibody, Mouse Monoclonal Antibody
Buy quality mouse FGF2 antibody (interacts with n/a), anti-FGF2, bFGF antibody, mouse monoclonal antibody, bFGF Antibody, Mouse Monoclonal Antibody (elisa ...
http://www.genwaybio.com/product_info.php?products_id=240514...

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FGF-2 (H-131) Antibody sc-7911
See how others have used FGF-2 (H-131): sc-7911 antibody and or FGF-2 (H-131) ... Antibodies tested include FGF-2 (N-19): sc-1390 (A), FGF-2 (H-131): ...
http://www.scbt.com/datasheet-7911-fgf-2-h-131-antibody.html...

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FGF2 antibody, FGF BASIC Antibody, Mouse Monoclonal Antibody
Buy quality mouse FGF2 antibody (interacts with human), anti-FGF2, FGF BASIC antibody, mouse monoclonal antibody, FGF BASIC Antibody, Mouse Monoclonal ...
http://www.genwaybio.com/product_info.php?products_id=70451...

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FGF-2 (A-7) Antibody sc-74413
FGF-2 shRNA (h) Lentiviral Particles, sc-39446-V, 200 µl ... FGF-2 (A-7): sc- 74413. Western blot analysis of human recombinant FGF-2. Download ...
http://www.scbt.com/datasheet-74413-fgf-2-a-7-antibody.html...

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F5537 Anti-Fibroblast Growth Factor-Basic antibody produced in ...
Immunogen, recombinant human FGF2 expressed in Escherichia coli. Specificity, The antibody does not cross-react with recombinant human FGF1, IL-1α, IL-1β, ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=F553...

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