|
| |
FGF4
| Symbol: | FGF4 | | Name(s): | fibroblast growth factor 4 (heparin secretory transforming protein 1, Kaposi sarcoma oncogene) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | HBGF-4, HST, HST-1, HSTF1, K-FGF, KFGF | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
|
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17852409 |
FGF-4 increases the rate at which MSC proliferate and has no significant effect on MSC pluripotency |
| 17390055 |
Both myeov and hst (fgf4) are normally situated approximately 475-kb apart at band 11q13, a region that is frequently amplified and overexpressed in various tumours. |
| 12163055 |
Differential effects of FGF4, EGF and TGFB1 on functional development of stromal layers (progenitor cell-outputs) in acute myeloid leukemia |
| 12008951 |
possible role of fibroblast growth factors in expression of genes of the plasminogen activator system in breast fibroblasts |
| 11840335 |
activation of human HST-1 gene in transgenic mice induces spermatogenesis and prevents adriamycin-induced testicular toxicity |
| 12841847 |
FGF4 is upregulated by the OCT3 transcription factor in breast cancer cells. |
| 14980503 |
HST-1 protects male germ cells from apoptosis under heat-stress condition in a mouse model. |
| 12172783 |
results show that Hensen's node and FGFs induce ectopic expression of cardiac lineage markers, and that FGF and TGFbeta family members can modulate early development of the heart |
Interacting gene products |
| Interaction Type |
Gene 1 |
Gene 2 |
Interaction description |
Complex |
Publication Link |
| BIND | fibroblast growth factor 4 precursor | neuropilin 1 | NRP1 (Npn-1) interacts with FGF4. This interaction was modeled on a demonstrated interaction between rat NRP1 and human FGF4. | - | Pubmed |
Recent Publications on FGF4: |  |
Early alteration of the self-renewal/differentiation threshold in trophoblast stem cells derived from mouse embryos after nuclear transfer.
Development after nuclear transfer (NT) is subjected to defects... | 3rd November, 2009
| INRA, UMR 1198 Biologie du Developpement et Reproduction, F-78352 Jouy en
| Dev Biol. 2009 Oct 15;334(2):325-34. Epub 2009 Jul 23.
DOI Direct Link |
BMP inhibition initiates neural induction via FGF signaling and Zic genes.
Neural induction is the process that initiates nervous system development... | 7th October, 2009
| Institut de Biologie du Developpement de Marseille Luminy, UMR 6216,
| Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17437-42. Epub 2009 Sep 28.
DOI Direct Link |
FGF4 independent derivation of trophoblast stem cells from the common vole.
The derivation of stable multipotent trophoblast stem (TS) cell lines from... | 25th September, 2009
| Institute of Cytology and Genetics, Russian Academy of Sciences, Siberian
| PLoS One. 2009 Sep 24;4(9):e7161.
DOI Direct Link |
Morphogenesis and cytodifferentiation of the avian retinal pigmented epithelium require downregulation of Group B1 Sox genes.
The optic vesicle is a multipotential primordium of the retina, which... | 22nd September, 2009
| University of California San Francisco, Cardiovascular Research Institute,
| Development. 2009 Aug;136(15):2579-89. Epub 2009 Jul 1.
DOI Direct Link |
PARP1 poly(ADP-ribosyl)ates Sox2 to control Sox2 protein levels and FGF4 expression during embryonic stem cell differentiation.
Transcription factors Oct4 and Sox2 are key players in maintaining the... | 15th September, 2009
| Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Chinese
| J Biol Chem. 2009 Aug 14;284(33):22263-73. Epub 2009 Jun 16.
DOI Direct Link |
→View more research publications. |
FGF4 results (if any) from reagent suppliers | 
|
Search Bioportfolio and other Life Science Sites for FGF4,
or search for FGF4 on BioPortfolio's antibody search engine.
This page has been viewed 450 times
Recent Search Terms used to find this page: who is the secretor of fgf4 | HBGF-4 protein | fgf4 binding protein | what was the reason for the discovery of fgf4 retrogene in dogs | FGF4 human fibroblast marker | fgf-4 heparin binding | fgf4 overexpression pluripotent ES | an expressed fgf4 retrogene is associated with breed-defining chondrodysplasia in domestic dogs | Activin promotes differentiation of cultured mouse trophoblast stem cells towards a labyrinth cell fate. | .
Resources from the NCBI used on this page, NCBI's standard disclaimer applies.
|
