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FHL2
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17975004 |
These results suggest a novel indirect mechanism of androgen action on FHL2 expression and provide evidence that SRF is an important determinant of AR action in prostate cancer cells. |
| 16378916 |
specific expression in tumor tissue points to an important functional role of FHL2 in human breast cancer |
| 15692560 |
FHL2 inhibits FOXO1 activity in prostate cancer cells by promoting the deacetylation of FOXO1 by SIRT1 |
| 17145880 |
Data suggest that nuclear FHL2 may serve as a novel biomarker predictive for prostate cancer with aggressive biology and point to a role of FHL2 in constitutive activation of AR-mediated growth signals. |
| 16311053 |
In conclusion, our findings are consistent with the hypothesis that FHL-2 and ADAM-9 are important modulators of IGFBP-5 actions and are, in part, regulated in a coordinated manner in bone. |
| 11821401 |
Insulin-like growth factor-binding protein 5 (IGFBP-5) interacts with a four and a half LIM protein 2 (FHL2). |
| 14550570 |
-FHL2 interaction may be involved in transcriptional regulation and play a significant role in cancer cell growth |
| 15572674 |
The interaction and functional cooperation between FHL2, CITED4, and CTNNB were studied. |
| 12145280 |
evidence of a functional interaction between the promyelocytic leukemia zinc finger protein (PLZF) and DRAL/FHL2 |
| 15117962 |
FHL2 and FHL3, respectively, are colocalized with alpha(7)beta(1) integrin receptor at the periphery of Z-discs, suggesting a role in mechanical stabilization of muscle cells | →View more information from publications. |
Recent Publications on FHL2: |  |
Hematopoietic stem cell transplantation for familial hemophagocytic lymphohistiocytosis and Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in Japan.
BACKGROUND: Post-transplant outcomes of hemophagocytic lymphohistiocytosis... | 15th October, 2009
| Department of Pediatrics, Graduate School of Medical Sciences, Kyushu
| Pediatr Blood Cancer. 2009 Oct 13.
DOI Direct Link |
Four and a half LIM domain 2 alters the impact of aryl hydrocarbon receptor on androgen receptor transcriptional activity.
Aryl hydrocarbon receptor (AhR) ligands modulate androgen receptor (AR)... | 10th October, 2009
| Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto,
| J Steroid Biochem Mol Biol. 2009 Oct 6.
DOI Direct Link |
Enhanced expression of FHL2 leads to abnormal myelopoiesis in vivo.
FHL2 is a multifunctional LIM domain protein that acts as a... | 24th September, 2009
| Section of Hematology/Oncology and the Cancer Research Center, University
| Leukemia. 2009 Sep;23(9):1650-7. Epub 2009 Apr 16.
DOI Direct Link |
Truncation of titin's elastic PEVK region leads to cardiomyopathy with diastolic dysfunction.
RATIONALE: The giant protein titin plays key roles in myofilament assembly... | 23rd September, 2009
| Department of Physiology, Sarver Molecular Cardiovascular Research
| Circ Res. 2009 Sep 11;105(6):557-64. Epub 2009 Aug 13.
DOI Direct Link |
Functional gene silencing mediated by chitosan/siRNA nanocomplexes.
Chitosan/siRNA nanoparticles to knock down FHL2 gene expression were... | 16th September, 2009
| Department of Pharmaceutical Science, Zhujiang Hospital, Southern Medical
| Nanotechnology. 2009 Oct 7;20(40):405103. Epub 2009 Sep 14.
DOI Direct Link |
→View more research publications. |
FHL2 results (if any) from reagent suppliers | 
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FHL2 antibody (ab12327) | Abcam
Rabbit polyclonal to FHL2. FHL2 is a LIM protein, all of which contain a highly conserved double zinc finger motif called the LIM domain.
http://www.abcam.com/FHL2-antibody-ab12327.html...
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FHL-2 (F4B2-B11) Antibody sc-52667
FHL-2 shRNA (h) Lentiviral Particles, sc-37891-V, 200 µl ... Western blot analysis of FHL-2 expression in HeLa (A), A-10 (B) and Sol8 (C) nuclear extracts
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http://www.scbt.com/datasheet-52667-fhl-2-f4b2-b11-antibody....
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MONOCLONAL ANTIBODY TO HUMAN FHL2
FHL2 seems to be a promiscuous coactivator because it modulates the activity of the ... The F4B2-B11 antibody is cross reactive with mouse and rat FHL2. ...
http://www.hbt.nl/HM2136.pdf...
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FHL-2 (C-16) Antibody sc-13409
See how others have used FHL-2 (C-16): sc-13409 antibody and or FHL-2 (C-16) ... Western blot analysis of FHL-2 expression in non-transfected: sc-117752 (A) ...
http://www.scbt.com/datasheet-13409-fhl-2-c-16-antibody.html...
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FHL2, Clone F4B2-B11, Human mAb
FHL2 shows specific interaction with beta-catenin, which requires the intact structure of all four LIM domains of FHL2 and the N-terminus plus the first ...
http://www.cellsciences.com/PDF/HM2136.pdf...
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FHL Antibody / FHL Antibodies
FHL-2 (C-16) Antibody, sc-13409, goat IgG, C-terminus (h), WB, IP, IF, ELISA, m, r, h. FHL-2 (E-16) Antibody, sc-23177, goat IgG, internal (h), WB, IP, IF, ...
http://www.scbt.com/table-fhl.html...
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FHL2 proteins and peptides: Chromatin and Nuclear Signaling ...
FHL2 proteins and peptides. ... Applications (see key) & Reactivity (see key). Image Abreview Publication. ab40396 · FHL2 peptide. BL, IP, WB, ICC/IF, Dot ...
http://www.abcam.com/index.html?t=77522&pt=2&c=3405&ei=&mu=r...
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