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AAK1
| Symbol: | AAK1 | | Name(s): | AP2 associated kinase 1 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | DKFZp686F03202, DKFZp686K16132, FLJ23712, FLJ25931, FLJ31060, FLJ42882, FLJ45252, KIAA1048, MGC138170, MGC164568, MGC164570 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17494869 |
These observations suggest that AAK1 functions at multiple steps of the endosomal pathway by regulating transferrin internalization and its rapid recycling back to the plasma membrane from early/sorting endosome. |
Recent Publications on AAK1: |  |
Genomewide association study for onset age in Parkinson disease.
BACKGROUND: Age at onset in Parkinson disease (PD) is a highly heritable... | 8th October, 2009
| Boston University School
| BMC Med Genet. 2009 Sep 22;10:98.
DOI Direct Link |
AAK1 regulates Numb function at an early step in clathrin-mediated endocytosis.
Numb is an endocytic protein that is proposed to influence clathrin-coated... | 14th January, 2009
| Department of Genetics, Cell Biology and Development, University of
| Traffic. 2008 Sep;9(10):1791-800. Epub 2008 Jul 24.
DOI Direct Link |
Kinase requirements in human cells: II. Genetic interaction screens identify kinase requirements following HPV16 E7 expression in cancer cells.
Human papillomavirus (HPV) oncoproteins subvert cellular signaling... | 17th December, 2008
| The Channing Laboratory, Brigham and Women's Hospital and Department of
| Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16478-83. Epub 2008 Oct 23.
DOI Direct Link |
Coordinated regulation of AP2 uncoating from clathrin-coated vesicles by rab5 and hRME-6.
Here we investigate the role of rab5 and its cognate exchange factors... | 19th November, 2008
| Department of Biomedical Science, University of Sheffield, Sheffield S10
| J Cell Biol. 2008 Nov 3;183(3):499-511.
DOI Direct Link |
The in vivo phosphorylation sites in multiple isoforms of amphiphysin I from rat brain nerve terminals.
Amphiphysin I (amphI) is dephosphorylated by calcineurin during nerve... | 22nd August, 2008
| Cell Signalling Unit, Children's Medical Research Institute, The
| Mol Cell Proteomics. 2008 Jun;7(6):1146-61. Epub 2008 Mar 14.
DOI Direct Link |
→View more research publications. |
AAK1 results (if any) from reagent suppliers | 
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