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DAAM1


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Gene DB Home
Symbol:DAAM1
Name(s):dishevelled associated activator of morphogenesis 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:FLJ41657, KIAA0666
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18162551 a carboxyl-terminal binding partner, Dvl, has a role in activation of Daam1
17986009 Crystal structure of human DAAM1 formin homology 2 domain
16630611 DAAM1 was shown to bind to the SH3 domain of CIP4 in vivo.
17021034 Results report that Profilin1 is an effector downstream of Daam1 required for cytoskeletal changes during gastrulation.
17482208 The DAAM1 FH2 domain structure, determined at 2.25 A resolution, and DAAM1 actin binding activity

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDras homolog gene family, member Adishevelled-associated activator of morphogenesis 1--Pubmed
HPRDdishevelled 1dishevelled-associated activator of morphogenesis 1--Pubmed
HPRDdishevelled 1dishevelled-associated activator of morphogenesis 1--Pubmed

Recent Publications on DAAM1:

Pubmed Logo
Wnt pathway reprogramming during human embryonal carcinoma differentiation and potential for therapeutic targeting.
ABSTRACT: BACKGROUND: Testicular germ cell tumors (TGCTs) are classified...
31st October, 2009
BMC Cancer. 2009 Oct 29;9(1):383.
DOI Direct Link
Non-redundant roles for Profilin2 and Profilin1 during vertebrate gastrulation.
Gastrulation is a critical morphogenetic event during vertebrate...
10th September, 2009
Department of Biochemistry, Robert Wood Johnson School of Medicine, Dev Biol. 2009 Aug 15;332(2):396-406. Epub 2009 Jun 11.
DOI Direct Link
The noncanonical WNT pathway is operative in idiopathic pulmonary arterial hypertension.
Idiopathic pulmonary arterial hypertension (IPAH) is a fatal disease that...
20th June, 2009
Department of Internal Medicine, University Hospital of Giessen, Giessen, Am J Respir Cell Mol Biol. 2009 Jun;40(6):683-91. Epub 2008 Nov 21.
DOI Direct Link
The planar cell polarity pathway directs parietal endoderm migration.
Parietal endoderm (PE) contributes to the yolk sac and is the first...
19th June, 2009
Department of Biology, Wesleyan University, Hall-Atwater Laboratories, Dev Biol. 2009 Jun 1;330(1):44-53. Epub 2009 Mar 21.
DOI Direct Link
Localization of the Diaphanous-related formin Daam1 to neuronal dendrites.
The Rho family of small GTPase proteins are involved in the formation and...
15th April, 2009
Center for Research in Neuroscience, McGill University Health Centre Neurosci Lett. 2008 Dec 5;447(1):62-7. Epub 2008 Sep 25.
DOI Direct Link

View more research publications.

DAAM1 results (if any) from reagent suppliers

Google CSE Logo
DAAM1 (N-17) Antibody sc-55930
DAAM1 shRNA (h) Lentiviral Particles, sc-62190-V, 200 µl ... Western blot analysis of DAAM1 expression in mouse embryo brain tissue extract. Download ...
http://www.scbt.com/datasheet-55930-daam1-n-17-antibody.html...

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Phospho-DAAM1-pT361 Antibody
Dot blot analysis of anti-Phospho-DAAM1-pT361 Antibody (Cat.#AP3550a) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot
...
http://www.abgent.com/products/catalog_no/AP3550a_Phospho_DA...

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DAAM1 (h): 293T Lysate sc-116973
DAAM1 (WW-3): sc-100942. Western blot analysis of DAAM1 expression in non- transfected: sc-117752 (A) and human DAAM1 transfected: sc-116973 (B) 293T whole
...
http://www.scbt.com/datasheet-116973-daam1-h-293t-lysate.htm...

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Abgent - Cell and Structure Antibodies - Cell_structure
AP7533a, CrkRS (CRK7) Antibody (N-term), WB, E, H, M. AP2720b, DAAM1 Antibody (C -term), WB, IHC, E, H. AP2720a, DAAM1 Antibody (N-term), WB, IHC, E, H ...
http://www.abgent.com/products/category/cell_function/cell_s...

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DAAM Antibody / DAAM Antibodies
DAAM1 (N-17) Antibody, sc-55930, goat IgG, N-terminus (h), WB, IP, IF, ELISA, m, r, h. DAAM1 (WW-3) Antibody, sc-100942, mouse IgG2a, FL (h), WB, IP, ELISA ...
http://www.scbt.com/table-daam.html...

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Abgent - Stem Cell
AP7059a, Creatine Kinase BB (CKB) Antibody (N-term), WB, E, H, M. AP2720b, DAAM1 Antibody (C-term), WB, IHC, E, H. AP2720a, DAAM1 Antibody (N-term) ...
http://www.abgent.com/products/category/stem_cell...

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DAAM1 siRNA (m) sc-62191
Click here for details. suitable control antibody: DAAM1 (N-17): sc-55930; sqRT- PCR Primer also available: DAAM1 (m)-PR: sc-62191, 20 µl ...
http://www.scbt.com/ko/datasheet-62191-daam1-sirna-m.html...

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