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AOF2
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17529991 |
The LSD1 active site cannot productively accommodate more than three residues on the N-terminal side of the methyllysine, explaining its histone H3-K4 specificity. |
| 17511474 |
Pull down of spiked and endogenous LSD1 from HeLa cell nuclear extracts, set the stage for activity-based demethylase proteomics. |
| 17687328 |
findings couple the function of BHC80 to that of LSD1, and indicate that unmodified H3K4 is part of the 'histone code'
'194526 |
| 17409384 |
LSD1 has a pro-oncogenic function by modulating pro-survival gene expression and p53 transcriptional activity |
| 17504018 |
This review underscores the involvement of the first histone demethylase, lysine-specific demethylase-1, in transcriptional regulation and describes a dynamic view of histone methylation by an array of other antagonizing histone-modifying enzymes. |
| 17367163 |
Tranylcypromine is a mechanism-based inactivator of LSD1. |
| 15620353 |
results thus identify a histone demethylase conserved from S. pombe to human and reveal dynamic regulation of histone methylation by both histone methylases and demethylases |
| 17145880 |
Data suggest that LSD1 may serve as novel biomarker predictive for prostate cancer with aggressive biology and point to a role of LSD1 in constitutive activation of AR-mediated growth signals. |
| 17277772 |
JMJD2C and LSD1 interact and both demethylases cooperatively stimulate androgen receptor-dependent gene transcription. |
| 16079794 |
nucleosomal demethylation is the result of CoREST enhancing the association between BHC110 and nucleosomes | →View more information from publications. |
Recent Publications on AOF2: |  |
Pomalidomide and lenalidomide induce p21 WAF-1 expression in both lymphoma and multiple myeloma through a LSD1-mediated epigenetic mechanism.
Lenalidomide and pomalidomide have both been evaluated clinically for... | 8th October, 2009
| Celgene, San Diego, California 92121, USA.
| Cancer Res. 2009 Sep 15;69(18):7347-56. Epub 2009 Sep 8.
DOI Direct Link |
New roles of flavoproteins in molecular cell biology.
Lysine-specific demethylase 1 (LSD1) exerts pathway-specific activity in... | 1st October, 2009
| University of Zaragoza, Spain.
| FEBS J. 2009 Aug;276(16):4289. Epub 2009 Jul 14.
DOI Direct Link |
New roles of flavoproteins in molecular cell biology: histone demethylase LSD1 and chromatin.
Lysine-specific demethylase 1 (LSD1) is an enzyme that removes methyl... | 1st October, 2009
| Dipartimento di Genetica e Microbiologia, Universita di Pavia, Italy.
| FEBS J. 2009 Aug;276(16):4304-12. Epub 2009 Jul 14.
DOI Direct Link |
LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer.
Lysine-specific demethylase 1 (LSD1) exerts pathway-specific activity in... | 24th September, 2009
| Department of Biochemistry and Molecular Biology, Peking University Health
| Cell. 2009 Aug 21;138(4):660-72.
DOI Direct Link |
Recent advances in the development of polyamine analogues as antitumor agents.
Lysine-specific demethylase 1 (LSD1) is an enzyme that removes methyl... | 22nd September, 2009
| Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University,
| J Med Chem. 2009 Aug 13;52(15):4551-73.
DOI Direct Link |
→View more research publications. |
AOF2 results (if any) from reagent suppliers | 
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AOF2 antibody, amine oxidase (flavin containing) domain 2 (AOF2 ...
Buy quality mouse AOF2 antibody (interacts with human), anti-AOF2, amine oxidase (flavin containing) domain 2 (AOF2),transcript variant 2 antibody, ...
http://www.genwaybio.com/product_info.php?products_id=60153...
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L7293 Monoclonal Anti-LSD1 (AOF2) antibody produced in mouse ~2 mg ...
L7293 Monoclonal Anti-LSD1 (AOF2) antibody produced in mouse ~2mg/mL, clone LSD1 -12, purified immunoglobulin, buffered aqueous solution.
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...
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Cayman Chemical | LSD1 (human recombinant) | Description • NPAO ...
10245 LSD1 (human recombinant). NPAO; AOF2; KDM1; p110b; BHC110; Lysine-specific demethylase-1. Click image to enlarge. • See below for pricing and ordering ...
http://www.caymanchem.com/app/template/Product.vm/catalog/10...
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LSD1 Antibody (C-term)
(TOP) Western blot analysis of AOF2 (arrow) using LSD1 Antibody (C-term) (Cat.# AP1218c). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or ...
http://www.abgent.com/products/catalog_no/AP1218c...
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LSD1 (Lysine-specific histone demethylase 1; aka AOF2, BHC110 ...
LSD1 (Lysine-specific histone demethylase 1; aka AOF2, BHC110, KIAA0601) (human, recombinant). CATALOG NO.: SE-544. LOT NO.: Temp. DESCRIPTION: MW=78 kDa, ...
http://www.biomol.com/SiteData/docs/ProductData/SE544.pdf...
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Antibodies to Transcription Regulators
L4418, Anti-LSD1 (AOF2) (C-terminal) antibody produced in rabbit, (polyclonal) ..... L7293, Monoclonal Anti-LSD1 (AOF2) antibody produced in mouse ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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LSD1 (C-19) Antibody sc-49291
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, AOF2, 23028, 1p36.12, NM_015013 ...
http://www.scbt.com/datasheet-49291-lsd1-c-19-antibody.html...
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