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JMJD2C
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17611647 |
JMJD2C is the histone demethylase implicated in the epigenetic reprogramming during the early embryogenesis. |
| 17277772 |
JMJD2C and LSD1 interact and both demethylases cooperatively stimulate androgen receptor-dependent gene transcription. |
| 16732293 |
GASC1 interacts with H3K9me3; three members of this subfamily of proteins demethylate H3K9me3/me2 in vitro through a hydroxylation reaction requiring iron and alpha-ketoglutarate as cofactors |
Recent Publications on JMJD2C: |  |
Jmjd2c histone demethylase enhances the expression of Mdm2 oncogene.
Jmjd2c is a candidate oncogene that encodes histone lysine demethylase. In... | 15th October, 2009
| Division of Functional Genomics, Molecular & Cellular Targeting
| Biochem Biophys Res Commun. 2009 Nov 13;389(2):366-71. Epub 2009 Sep 2.
DOI Direct Link |
The Histone Demethylase JMJD2C Is Stage-Specifically Expressed in Preimplantation Mouse Embryos and Is Required for Embryonic Development.
Epigenetic modifications play a pivotal role in embryonic development by... | 22nd August, 2009
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| Biol Reprod. 2009 Aug 19.
DOI Direct Link |
Synthesis and activity of N-oxalylglycine and its derivatives as Jumonji C-domain-containing histone lysine demethylase inhibitors.
N-Oxalylglycine (NOG) derivatives were synthesized, and their inhibitory... | 30th June, 2009
| Nagoya City University, Tanabe-dori, Mizuho-ku, Aichi, Japan.
| Bioorg Med Chem Lett. 2009 May 15;19(10):2852-5. Epub 2009 Mar 26.
DOI Direct Link |
Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1alpha.
The transcription factor HIF (hypoxia-inducible factor) mediates a highly... | 31st January, 2009
| Henry Wellcome Building for Molecular Physiology, University of Oxford,
| Biochem J. 2008 Dec 15;416(3):387-94.
DOI Direct Link |
Mucosa-associated lymphoid tissue lymphoma: novel translocations including rearrangements of ODZ2, JMJD2C, and CNN3.
PURPOSE: The well-known translocations identified in MALT lymphomas... | 17th December, 2008
| Department of Pathology and Internal Medicine 1, Medical University of
| Clin Cancer Res. 2008 Oct 15;14(20):6426-31.
DOI Direct Link |
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JMJD2C results (if any) from reagent suppliers |
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