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SARM1


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Symbol:SARM1
Name(s):sterile alpha and TIR motif containing 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:FLJ36296, KIAA0524, SAMD2, SARM
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18089857 SARM1 deficiencies may uncover unexpected similarities between the ways in which neurons and immune cells sense and respond to danger.
17804407 confirmed the co-localization of retinoschisin with Na/K ATPase and SARM1 in photoreceptors and bipolar cells of retina tissue
15893701 Candidate gene in the onset of hereditary infectious/inflammatory diseases.
16964262 TIR adaptor SARM is a negative regulator of Toll-like receptor signaling.

Recent Publications on SARM1:

Pubmed Logo
Endotoxin tolerance dysregulates MyD88- and Toll/IL-1R domain-containing adapter inducing IFN-beta-dependent pathways and increases expression of negative regulators of TLR signaling.
Endotoxin tolerance reprograms cell responses to LPS by repressing...
21st October, 2009
Department of Microbiology and Immunology, University of Maryland School J Leukoc Biol. 2009 Oct;86(4):863-75. Epub 2009 Aug 5.
DOI Direct Link
Signalling adaptors used by Toll-like receptors: an update.
Research into the five Toll/IL1 receptor (TIR) adaptor proteins involved...
17th December, 2008
School of Biochemistry and Immunology, Trinity College, Dublin, Ireland. Cytokine. 2008 Sep;43(3):342-9. Epub 2008 Aug 15.
DOI Direct Link
SARM: a novel Toll-like receptor adaptor, is functionally conserved from arthropod to human.
Sterile-alpha and Armadillo motif containing protein (SARM) was recently...
23rd August, 2008
Department of Biological Sciences, National University of Singapore, 14 Mol Immunol. 2008 Mar;45(6):1732-42. Epub 2007 Nov 5.
DOI Direct Link
Studies of SARM1 uncover similarities between immune and neuronal responses to danger.
Toll-interleukin-1 receptor (TIR) domain-containing proteins are best...
17th January, 2008
Universite de la Mediterranee, Centre d'Immunologie de Marseille-Luminy, Sci STKE. 2007 Dec 18;2007(417):pe73.
DOI Direct Link
Retinoschisin (RS1), the protein encoded by the X-linked retinoschisis gene, is anchored to the surface of retinal photoreceptor and bipolar cells through its interactions with a Na/K ATPase-SARM1 complex.
Retinoschisin or RS1 is a discoidin domain-containing protein encoded by...
13th December, 2007
Department of Biochemistry & Molecular Biology, Centre for Macular J Biol Chem. 2007 Nov 9;282(45):32792-801. Epub 2007 Sep 5.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7528243 Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of breast cancer
5266094 Method relating to the production of amorphous test bodies

SARM1 results (if any) from reagent suppliers

Google CSE Logo
Innate Immunity Antibodies :: Page 4
RNF216 Antibody, 49-343, H, WB, IHC, Ring Finger Protein 216. SARM1 Monoclonal Antibody, 49-353, H, IHC, IP, Sterile Alpha And TIR Motif Containing 1 ...
http://www.prosci-inc.com/shop/catalog1/Innate-Immunity-Anti...

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SARM (C-20) Antibody sc-130620
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, SARM1, 23098, 17q11.2, Q6SZW1 ...
http://www.scbt.com/ko/datasheet-130620-sarm-c-20-antibody.h...

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SARM (C-20) Antibody sc-130620
Species, Nome del gene, Codice del gene, Locus cromosoma, Isoform (mRNA) Accession #, codice accesso proteina, Numero d' ordine. Human, SARM1, 23098,
17q11. ...
http://www.scbt.com/it/datasheet-130620-sarm-c-20-antibody.h...

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SARM Antibody / SARM Antibodies
SARM (C-20) Antibody, sc-130620, rabbit IgG, N/A, WB, m, h. SARM specific siRNA, sHRNA Plasmid과 shRNA Lentiviral Particles gene silencers 도 제공합니다. ...
http://www.scbt.com/ko/table-sarm.html...

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SARM siRNA (m) sc-62977
Species, 遺伝子名, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. マウス, Sarm1, 237868, 11 B5, Q6PDS3 ...
http://www.scbt.com/ja/datasheet-62977-sarm-sirna-m.html...

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SARM siRNA (m) sc-62977
... Numero de acesso de isoformas de RNA mensageiro, Numero de acesso de proteina, OMIM&trande; Numero. camundongo, Sarm1, 237868, 11 B5, Q6PDS3 ...
http://www.scbt.com/pt/datasheet-62977-sarm-sirna-m.html...

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