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JMJD3


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Gene DB Home
Symbol:JMJD3
Name(s):jumonji domain containing 3, histone lysine demethylase
Type:protein-coding
Organism:Homo sapiens
Synonyms:KIAA0346
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17923864 JMJD3 was identified as a demethylase capable of removing the trimethyl group from histone H3 lysine 27 and upregulated in prostate cancer.
18003914 JMJD3 demethylates di- and trimethylated lysine 27 of histone H3 in vitro and in cells.
17713478 the human JmjC-domain-containing proteins UTX and JMJD3 demethylate tri-methylated Lys 27 on histone H3

Recent Publications on JMJD3:

Pubmed Logo
Epigenetic regulation of the alternatively activated macrophage phenotype.
Alternatively activated (M2) macrophages play critical roles in diverse...
29th October, 2009
Immunology Program, Department of Pathology, University of Michigan Blood. 2009 Oct 8;114(15):3244-54. Epub 2009 Jun 30.
DOI Direct Link
Inhibition of succinate dehydrogenase dysregulates histone modification in mammalian cells.
Remodelling of mitochondrial metabolism is a hallmark of cancer. Mutations...
24th October, 2009
Department of Regenerative Cardiology, Centro Nacional de Investigaciones Mol Cancer. 2009 Oct 22;8:89.
DOI Direct Link
Epigenetic reprogramming during wound healing: loss of polycomb-mediated silencing may enable upregulation of repair genes.
Tissue repair is a complex process that requires wound-edge cells to...
16th October, 2009
Department of Biochemistry, School of Medical Sciences, University of EMBO Rep. 2009 Aug;10(8):881-6. Epub 2009 Jul 3.
DOI Direct Link
Jmjd3 contributes to the control of gene expression in LPS-activated macrophages.
Jmjd3, a JmjC family histone demethylase, is induced by the transcription...
26th September, 2009
Department of Experimental Oncology, European Institute of Oncology (IEO), EMBO J. 2009 Sep 24.
DOI Direct Link
Remodeling of the chromatin structure of the facioscapulohumeral muscular dystrophy (FSHD) locus and upregulation of FSHD-related gene 1 (FRG1) expression during human myogenic differentiation.
BACKGROUND: Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal...
27th August, 2009
Department of Biology and Genetics for Medical Sciences, University of BMC Biol. 2009 Jul 16;7:41.
DOI Direct Link

View more research publications.

BioNews Results for JMJD3

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Jmjd3 contributes to the control of gene expression in LPS-activated macrophages
EMBO Journal:  Nov 4 2009 12:12PM Matching: jmjd3

JMJD3 results (if any) from reagent suppliers

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KDM6B / JMJD3 antibody (ab38113) | Abcam
Rabbit polyclonal to KDM6B / JMJD3. KDM6B / JMJD3 is a 181 kDa jumonji C domain contain protein. KDM6B specifically demethylates di and tri histone H3 at ...
http://www.abcam.com/KDM6B-JMJD3-antibody-ab38113.html...

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JMJD3 Antibody #3457
Western blot analysis of extracts from HeLa cells, untransfected or transfected with human or mouse JMJD3, using JMJD3 Antibody. ...
http://www.cellsignal.com/products/3457.html...

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Mouse JMJD3 Antibody (C-term)
Western blot analysis of anti-JMJD3 C-term Pab (Cat. #AP1022b) in untransfected 293 cells (left) and transfected 293 cells (right). ...
http://www.abgent.com/catalog_no/AP1022b_Mouse_JMJD3_Antibod...

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JMJD3 Antibody
Specificity/Sensitivity: JMJD3 Antibody detects trans- fected levels of JMJD3 protein. ... coupled) corresponding to the human JMJD3 protein. ...
http://www.cellsignal.com/pdf/3457.pdf...

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JMJD3 (N-24) Antibody sc-130157
JMJD3 (N-24): sc-130157. Immunoperoxidase staining of formalin fixed, ... Western blot analysis of JMJD3 expression in 293 whole cell lysates. Download
...
http://www.scbt.com/datasheet-130157-jmjd3-n-24-antibody.htm...

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JMJD3 Antibody (N-term)
Western blot analysis of anti-JMJD3 N-term Pab (AP1022a) in Hela cell line lysates. JMJD3 N-term(arrow) was detected using the purified Pab. ...
http://www.abgent.com/products/catalog_no/AP1022a_JMJD3_Anti...

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JMJD Antibody / JMJD Antibodies
JMJD3 (N-24) Antibody, sc-130157, rabbit IgG, N/A, WB, IP, IF, IHC(P),ELISA, human ... JMJD3 shRNA Plasmid (m): sc-146326-SH. JMJD3 shRNA (m) ...
http://www.scbt.com/table-jmjd.html...

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