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EPB41L3
| Symbol: | EPB41L3 | | Name(s): | erythrocyte membrane protein band 4.1-like 3 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | 4.1B, DAL-1, DAL1, FLJ37633, KIAA0987 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 16420693 |
These results suggest that protein methylation cooperates with DAL-1/4.1B-associated caspase 8-specific activation to induce apoptosis in breast cancer cells. |
| 17640904 |
suggest a more general role for Protein 4.1B as a negative regulator of cancer progression to metastatic disease |
| 17260099 |
TSLC1 and DAL-1 are involved in the pathogenesis of breast cancer and are frequently inactivated by methylation |
| 16152585 |
promoter methylation of the 4.1B is one of the most frequent epigenetic alterations in RCCC and could predict the metastatic recurrence of the surgically resected RCCC |
| 15334060 |
DAL-1/4.1B protein significantly inhibits PRMT3 methylation of cellular substrates, which may affect mechanism through which DAL-1/4.1B affects tumor cell growth. |
| 15517334 |
protein 4.1B in mouse small intestine & DAL-1 in human colon showed similar distributions in normal intestinal epithelial cells; expression reduced in intestinal carcinoma; may function in preventing malignant transformation of intestinal epithelial cells |
| 15688033 |
U2 domain, when properly targeted to the plasma membrane, contains all the residues necessary for mediating Protein 4.1B growth suppression. |
| 15837747 |
DAL-1 methylation is involved in the development and progression of non-small cell lung cancers and provides an indicator for poor prognosis. |
| 12234973 |
TSLC1 and DAL-1, two distinct tumor suppressor proteins, directly associate in lung cancer. |
| 12478663 |
DAL-1 has a role in the development of multiple meningioma and does not function as a tumor suppressor | →View more information from publications. |
Recent Publications on EPB41L3: |  |
A Golgi-associated protein 4.1B variant is required for assimilation of proteins in the membrane.
The archetypal membrane skeleton is that of the erythrocyte, consisting... | 12th June, 2009
| Red Cell Physiology Laboratory, New York Blood Center, New York, NY 10065,
| J Cell Sci. 2009 Apr 15;122(Pt 8):1091-9. Epub 2009 Mar 19.
DOI Direct Link |
Frequent concomitant epigenetic silencing of the stress-responsive tumor suppressor gene CADM1, and its interacting partner DAL-1 in nasal NK/T-cell lymphoma.
Nasal NK/T-cell lymphoma (NL) is a rare but clinically important entity of... | 4th March, 2009
| Johns Hopkins Singapore, Singapore.
| Int J Cancer. 2009 Apr 1;124(7):1572-8.
DOI Direct Link |
Potential role of EPB41L3 (protein 4.1B/Dal-1) as a target for treatment of advanced prostate cancer.
BACKGROUND: Loss of erythrocyte membrane protein band 4.1-like 3 (EPB41L3;... | 30th August, 2008
| Monash University, Centre for Cancer Research, Monash Institute of Medical
| Expert Opin Ther Targets. 2008 Jul;12(7):845-53.
DOI Direct Link |
The tumor suppressor DAL-1/4.1B and protein methylation cooperate in inducing apoptosis in MCF-7 breast cancer cells.
BACKGROUND : DAL-1 (Differentially Expressed in Adenocarcinoma of the... | 2nd April, 2008
| Hermlein Brain Tumor Center, Department of Neurosurgery, Henry Ford
| Mol Cancer. 2006 Jan 18;5:4.
DOI Direct Link |
In vivo differentiation and genomic evolution in adult male germ cell tumors.
Germ cell tumors (GCTs) are the most common solid malignancy in young... | 6th February, 2008
| Cell Biology Program, Sloan-Kettering Institute, New York, NY, USA.
| Genes Chromosomes Cancer. 2008 Jan;47(1):43-55.
DOI Direct Link |
→View more research publications. |
EPB41L3 results (if any) from reagent suppliers | 
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EPB41L3 proteins and peptides: Cancer > Oncoproteins/suppressors ...
EPB41L3 proteins and peptides. ... Applications (see key) & Reactivity (see key) . Image Abreview Publication. ab45836 · EPB41L3 peptide (1075-1087) ...
http://www.abcam.com/index.html?t=171706&pt=2&c=4340&ei=&mu=...
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4.1 Antibody / 4.1 Antibodies
PRODUCT NAME, CATALOG #, ISOTYPE, EPITOPE, APPLICATIONS, SPECIES. 4.1B (E-20) Antibody, sc-25964, goat IgG, internal (h), WB, IF, ELISA, m, r, h ...
http://www.scbt.com/table-4-1.html...
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Abcam antibodies and reagents product map
... ENC1 antibodies (1) · EPB41 antibodies (2) · EPB41L1 antibodies (1) · EPB41L3 antibodies (3) · EPB41L3 proteins and peptides (1) · EPS8L1 antibodies (
2) ...
http://www.abcam.com/index.html?c=2105...
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4.1 Antibody / 4.1 Antibodies
제품명, 카탈로그 번호, ISOTYPE, EPITOPE, APPLICATIONS, SPECIES. 4.1B (E-20) Antibody, sc-25964, goat IgG, internal (h), WB, IF, ELISA, m, r, h ...
http://www.scbt.com/ko/table-4-1.html...
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Abcam antibodies and reagents product map
... DNAJB4 antibodies (2) · DRG1 antibodies (1) · ENO1 antibodies (1) · EPB41L3 antibodies (3) · EPB41L3 proteins and peptides (1) · ERRFI1 antibodies (1) ...
http://www.abcam.com/index.html?pageconfig=productmap&cl=228...
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4.1B (K-18) Antibody sc-25965
Species, 遺伝子名, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. ヒト, EPB41L3, 23136, 18p11.31, NM_012307 ...
http://www.scbt.com/ja/datasheet-25965-4-1b-k-18-antibody.ht...
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4.1B (485) Antibody sc-100641
... Numéro d'accès d´isoforme d´ARNm, Numéro d'accès de la protéine, Numéro OMIM ™. Humain, EPB41L3, 23136, 18p11.31, NM_012307 · Q9Y2J2 ...
http://www.scbt.com/fr/datasheet-100641-4-1b-485-antibody.ht...
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