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MAPK8IP3


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Symbol:MAPK8IP3
Name(s):mitogen-activated protein kinase 8 interacting protein 3
Type:protein-coding
Organism:Homo sapiens
Synonyms:DKFZp762N1113, FLJ00027, JIP3, JSAP1, KIAA1066, SYD2
Links: Pubmed, Entrez Gene, GeneCards, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
15911620 JIP1 and JIP3, have a cross-talk that leads to the regulation of the ASK1-SEK1-JNK signal during glucose deprivation; cross-talk between JIP3 and JIP1 is mediated through SEK1-JNK2 and Akt1.
16141199 JSAP1.FAK complex functions cooperatively as a scaffold for the JNK signaling pathway and regulator of cell migration on FN
15532711 Pressure application of 160 mmHg for 3 h produced cell proliferation and activated ERK and c-JUN N-terminal kinase
12189133 demonstration that JSAP1 bound ASK1 and enhanced ASK1- and H2O2-induced JNK activity

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDkinesin 2 60/70kDamitogen-activated protein kinase 8 interacting protein 3 isoform 1--Pubmed
HPRDASK1mitogen-activated protein kinase 8 interacting protein 3 isoform 1--Pubmed
HPRDMAP3K11mitogen-activated protein kinase 8 interacting protein 3 isoform 1--Pubmed
HPRDJNK1mitogen-activated protein kinase 8 interacting protein 3 isoform 1--Pubmed
HPRDJNK2mitogen-activated protein kinase 8 interacting protein 3 isoform 1--Pubmed
HPRDJNK3mitogen-activated protein kinase 8 interacting protein 3 isoform 1--Pubmed
HPRDmitogen-activated protein kinase kinase 1mitogen-activated protein kinase 8 interacting protein 3 isoform 1--Pubmed
HPRDHomo sapiens mitogen-activated protein kinase kinase 7b mRNA, complete cds.mitogen-activated protein kinase 8 interacting protein 3 isoform 1--Pubmed
HPRDv-raf-1 murine leukemia viral oncogene homolog 1mitogen-activated protein kinase 8 interacting protein 3 isoform 1--Pubmed
HPRDv-raf-1 murine leukemia viral oncogene homolog 1mitogen-activated protein kinase 8 interacting protein 3 isoform 1--Pubmed

Recent Publications on MAPK8IP3:

Pubmed Logo
Co-operative versus independent transport of different cargoes by Kinesin-1.
Kinesin motors drive the intracellular transport of multiple cargoes along...
17th July, 2008
Department of Cell and Developmental Biology, University of Michigan, Ann Traffic. 2008 May;9(5):725-41. Epub 2008 Feb 11.
DOI Direct Link
Morphogenetic lung defects of JSAP1-deficient embryos proceeds via the disruptions of the normal expressions of cytoskeletal and chaperone proteins.
Recent studies have shown that JNK/stress-activated protein...
22nd April, 2008
Division of Nano Sciences and Brain Disease Research Institute, Ewha Proteomics. 2008 Mar;8(5):1071-80.
DOI Direct Link
"JIP"ing along the axon: the complex roles of JIPs in axonal transport.
JIPs are JNK interacting proteins and bind to JNK cascade kinases. JIP1...
28th March, 2008
NCBS-TIFR, Bellary Bioessays. 2008 Jan;30(1):10-4.
DOI Direct Link
Neural-specific ablation of the scaffold protein JSAP1 in mice causes neonatal death.
We previously identified c-Jun NH(2)-terminal kinase...
22nd March, 2008
Division of Molecular Cell Signaling, Department of Molecular and Cellular Neurosci Lett. 2007 Dec 11;429(1):43-8. Epub 2007 Oct 2.
DOI Direct Link
The amyloid-beta precursor protein is phosphorylated via distinct pathways during differentiation, mitosis, stress, and degeneration.
Phosphorylation of amyloid-beta precursor protein (APP) at Thr(668) is a...
6th December, 2007
Department of Pharmacology and Physiology, University of Medicine and Mol Biol Cell. 2007 Oct;18(10):3835-44. Epub 2007 Jul 18.
DOI Direct Link

View more research publications.

MAPK8IP3 results (if any) from reagent suppliers

Google CSE Logo
MAPK8IP3 Antibody (S583)
Abgent develops powerful tools to profile posttranslational modifications related to cellular function and disease. Abgent antibodies target protein
kinases ...
http://www.abgent.com/products/catalog_no/AP7282c/background...

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MAPK8IP3 Antibody (S583), AP7282c, 0.1mg, $235.00, $235.00. Shipping, flat fee, $35.00. Tax will be added to the Total after the order is processed. ...
https://www.abgent.com/store/add_to_cart/AP7282c...

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JIP-3 (E-18) Antibody sc-10428
Human, MAPK8IP3, 23162, 16p13.3, NM_001040439, NM_015133 · Q9UPT6 · 605431. Mouse, Mapk8ip3, 30957, 17 A3.3, Q9ESN9, N/A. Ordering Information ...
http://www.scbt.com/datasheet-10428-jip-3-e-18-antibody.html...

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View Cart
MAPK8IP3 Antibody (S583) Blocking Peptide, BP7282c, 0.1mg, $42.00, $42.00. Shipping, flat fee, $35.00. Tax will be added to the Total after the order is
...
https://www.abgent.com/store/add_to_cart/BP7282c...

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JSAP1 (V-18) Antibody sc-23401
Human, MAPK8IP3, 23162, 16p13.3, NM_001040439, NM_015133 · Q9UPT6 · 605431. Mouse, Mapk8ip3, 30957, 17 A3.3, Q9ESN9, N/A. Mouse, Spag9, 70834, 11 D, Q58A65
...
http://www.scbt.com/datasheet-23401-jsap1-v-18-antibody.html...

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Antibodies available - Antibodies | Imgenex
IMX-3204, JIP3/Syd2/JSAP1, Syd2, JSAP1, MAPK8IP3, FLJ00027, Purified, Peptide Affinity, N/A, Peptide ELISA*, 0.1 mg, N/A, View MSDS ...
http://www.imgenex.com/alphabetic_antibody_list.php?done=dis...

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Sheet1
353, CD289, TLR9, 110, pDC, B, mono, CpG DNA, innate immune response to bacteria or virus, BTK, TRIAD3, H-Ras, MAPK8IP3 ...
http://www.biolegend.com/media_assets/support_resource/BioLe...

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