Gene Information from Publications |
| Publication Link |
Summary of findings |
| 12707012 |
These results demonstrate that airway epithelial cells express the costimulatory molecule B7-H2, and suggest the possibility that B7-H2 may participate in antigen presentation by epithelial cells. |
| 16221208 |
Interaction of tubular epithelial cells and kidney infiltrating T cells via ICOS-L and B7-H1 may change the balance of positive and negative signals to the T cells |
| 12800259 |
ICOS-B7H costimulatory pathway may be involved in the negative regulation of cell-mediated immune responses. |
| 12456022 |
ICOS-L is a ligand for ICOS and plays an important functional role in the activation of memory T cells by endothelial cells [review] |
| 15047568 |
Expression of B7-H3 by nasal epithelial. Expands range of potential costimulatory signals through which these cells may interact with activated mucosal T lymphocytes. Extent of mucociliary differentiation of cultured cells may influence this capability. |
| 12960306 |
A critical role of the B7-like protein-ICOS costimulatory pathway is demonstrated in the pathogenesis of lupus nephritis. |
| 14603470 |
ICOSL protein and mRNA was expressed in 7 of 12 glioma cell lines and expression is upregulated by the inflammatory cytokine, tumor necrosis factor-alpha (TNF-alpha), whereas interferon-gamma (IFN-gamma) has no such effect |
| 17242332 |
ICOS-L may be relevant in inducing an acute immune response and may be critically involved in perpetuating inflammation in chronically immune-mediated disorders of the peripheral nervous system. |
| 16115907 |
Results indicate the expression of functional B7-H2 molecule may facilitate progression of acute myeloid leukemia. |
| 15131796 |
B7h-ICOS protein costimulatory pathway may be important in intestinal epithelial cell(iec):T-cell interactions. IEC expressed B7h and B7-H1. |
| 16951355 |
ICOSL receptor binding site is mediated solely by the immunoglobulin (Ig) variable domain but requires the Ig constant domain for maintaining structural integrity of the protein. |
