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FN1
| Symbol: | FN1 | | Name(s): | fibronectin 1 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | CIG, DKFZp686F10164, DKFZp686H0342, DKFZp686I1370, DKFZp686O13149, ED-B, FINC, FN, FNZ, GFND2, LETS, MSF | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17468934 |
ED-B fibronectin expression is closely associated with inflammation in atherosclerosis. |
| 18268355 |
dominant mutations in FN1 accounted for 40% of cases of Glomerulopathy with fibronectin (FN) deposits in our study group |
| 11605051 |
Observational study of gene-disease association. (HuGE Navigator) |
| 12497612 |
Observational study of gene-disease association. (HuGE Navigator) |
| 16375583 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17526550 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17879163 |
These findings provide evidence that mutations in fibronectin, induce anoikis in human squamous cell carcinoma cells by modulating integrin alpha v-mediated phosphorylation of FAK and ERK. |
| 18006840 |
expression of the alternatively spliced extra-domain A (EDA) of fibronectin in the neovasculature of metastases and primary tumors of human cancer patients was shown |
| 17949711 |
Fractionation of keratinocyte conditioned medium by size-exclusion chromatography revealed the presence of bioactive MSF as well as a functional inhibitor of MSF (MSFI) in fractions corresponding to approximately 70 kDa and 25 kDa, respectively. |
| 17526550 |
MspI and HaeIIIb FN gene polymorphisms may be clinically relevant to define the risk of lymphoma development in MCsn. | →View more information from publications. |
Recent Publications on FN1: |  |
Polyploidy impairs human aortic endothelial cell function and is prevented by nicotinamide phosphoribosyltransferase.
Polyploid endothelial cells are found in aged and atherosclerotic... | 23rd October, 2009
| 1The University of Western Ontario.
| Am J Physiol Cell Physiol. 2009 Oct 21.
DOI Direct Link |
Clinical relevance of nine transcriptional molecular markers for the diagnosis of head and neck squamous cell carcinoma in tissue and saliva rinse.
BACKGROUND: Analysis of 23 published transcriptome studies allowed us to... | 20th October, 2009
| Service d'ORL et Chirurgie Maxillo-faciale, Centre Hospitalier
| BMC Cancer. 2009 Oct 18;9:370.
DOI Direct Link |
Genome-wide transcriptomic profiling of microdissected human breast tissue reveals differential expression of KIT (c-Kit, CD117) and oestrogen receptor-alpha (ERalpha) in response to therapeutic radiation.
The pathogenesis of late normal tissue fibrosis after high-dose ionizing... | 10th October, 2009
| Breakthrough Breast Cancer Research Centre, Institute of Cancer Research,
| J Pathol. 2009 Sep;219(1):131-40.
DOI Direct Link |
A gene expression classifier of node-positive colorectal cancer.
We used digital long serial analysis of gene expression to discover gene... | 2nd October, 2009
| Department of Pathology, Microbiology and Immunology, University of South
| Neoplasia. 2009 Oct;11(10):1074-83.
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Inflammatory gene expression in response to sub-lethal ricin exposure in Balb/c mice.
The toxin ricin has been shown to cause inflammatory lung damage, leading... | 24th September, 2009
| Immunotoxicology Group, Biology, Biomedical Sciences, Defence Science and
| Toxicology. 2009 Oct 1;264(1-2):119-30. Epub 2009 Aug 12.
DOI Direct Link |
→View more research publications. |
FN1 results (if any) from reagent suppliers | 
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Fibronectin (EP5) Antibody sc-8422
CHROMOSOMAL LOCATION, Genetic locus: FN1 (human) mapping to 2q34; Fn1 (mouse) mapping to 1 36.1 cM (1 C1-C5).. SOURCE, Fibronectin (EP5) is a mouse ...
http://www.scbt.com/datasheet-8422-fibronectin-ep5-antibody....
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Antibodies to Extracellular Matrix Proteins
FN1(2335), human mouse, canine, chicken, rabbit, goat, bovine, ELISA (i), ICC, IF (i), ... FN1(2335), canine, rabbit, human, sheep, bovine, goat, chicken ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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PLAT antibody, PLASMINOGEN ACTIVATOR TYPE 1 (PAI-1) . E212/E220 ...
Domain: Both FN1 and one of the kringle domains are required for binding to fibrin. Domain: Both FN1 and EGF-like domains are important for binding to LRP1.
...
http://www.genwaybio.com/product_info.php?products_id=175244...
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F7387 Monoclonal Anti-Fibronectin antibody produced in mouse clone ...
indirect immunofluorescence: 1:200 using cultured human fibroblasts. microarray: suitable. isotype, IgG1. Gene Information, human ... FN1(2335). mouse . ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...
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Fibronectin (C-20) Antibody sc-6952
Human, FN1, 2335, 2q35, NM_002026, NM_054034, NM_212474, NM_212475, NM_212476, NM_212478, NM_212482 · P02751 · 135600. Mouse, Fn1, 14268, 1 C3, P11276 ...
http://www.scbt.com/datasheet-6952-fibronectin-c-20-antibody...
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F6140 Monoclonal Anti-Fibronectin, Cellular antibody produced in ...
indirect immunofluorescence: 1:400 using cultured chicken fibroblasts. radioimmunoassay: suitable. isotype, IgM. Gene Information, human ... FN1(2335)
...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...
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Fibronectin antibody [IST-9] (ab6328) | Abcam
Quantification of fibronectin 1 (FN1) splice variants, including two novel ones, and analysis of integrins as candidate FN1 receptors in bovine ...
http://www.abcam.com/Fibronectin-antibody-IST-9-ab6328.html...
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