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LARS2


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Gene DB Home
Symbol:LARS2
Name(s):leucyl-tRNA synthetase 2, mitochondrial
Type:protein-coding
Organism:Homo sapiens
Synonyms:KIAA0028, LEURS, MGC26121
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
15919814 Observational study of gene-disease association. (HuGE Navigator)
15737668 Upregulation of LARS2 is a hallmark of 324A>G mutation. The accumulation of 3243A>G mutation in the brain may have a pathophysiologic role in bipolar disorder and schizophrenia.
15919814 In this study, we provide evidence that the LARS2 gene may represent a novel type 2 diabetes susceptibility gene.

Recent Publications on LARS2:

Pubmed Logo
Genetic association analysis of LARS2 with type 2 diabetes.
AIMS/HYPOTHESIS: LARS2 has been previously identified as a potential type...
23rd October, 2009
Department of Molecular Cell Biology, Leiden University Medical Center Diabetologia. 2009 Oct 22.
DOI Direct Link
Inactivation of LARS2, located at the commonly deleted region 3p21.3, by both epigenetic and genetic mechanisms in nasopharyngeal carcinoma.
Allelic loss of chromosome 3p, including the 3p21.3 region, is found in...
11th April, 2009
Cancer Research Institute, Xiang-Ya School of Medicine, Central South Acta Biochim Biophys Sin (Shanghai). 2009 Jan;41(1):54-62.
Evidence that the mitochondrial leucyl tRNA synthetase (LARS2) gene represents a novel type 2 diabetes susceptibility gene.
Previously, we have shown that a mutation in the mitochondrial DNA-encoded...
5th August, 2005
Leiden University Medical Center, Department of Molecular Cell Biology, Diabetes. 2005 Jun;54(6):1892-5.
Mitochondrial DNA 3243A>G mutation and increased expression of LARS2 gene in the brains of patients with bipolar disorder and schizophrenia.
BACKGROUND: Accumulating evidence suggests mitochondrial dysfunction in...
17th May, 2005
Laboratory for Molecular Dynamics of Mental Disorders, RIKEN Brain Science Biol Psychiatry. 2005 Mar 1;57(5):525-32.
DOI Direct Link

LARS2 results (if any) from reagent suppliers

Google CSE Logo
LARS2 siRNA (m) sc-146655
Click here for details. suitable control antibody: contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: LARS2 ...
http://www.scbt.com/ko/datasheet-146655-lars2-sirna-m.html...

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Abgent - Metabolism Antibodies - Metabolism
... Ketohexokinase (KHK) Antibody (N-term), WB, E, H, M. AP7296bNEW, LAP3 Antibody (C-term), WB, IHC, E, H. AP7980aNEW, LARS2 Antibody (N-term), IHC, E, H
...
http://www.abgent.com/products/category/cell_function/metabo...

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LARS Antibody / LARS Antibodies
Lentiviral Particles: sc-78462-V. LARS2 siRNA (m): sc-146655. LARS2 shRNA Plasmid (m): sc-146655-SH. LARS2 shRNA (m) Lentiviral Particles: sc-146655-V ...
http://www.scbt.com/ko/table-lars.html...

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Abcam antibodies and reagents product map
... IARS2 antibodies (2) · Isoleucyl tRNA synthetase antibodies (3) · KIAA1970 antibodies (2) · LARS2 antibodies (1) · Leucyl tRNA synthetase antibodies (1)
...
http://www.abcam.com/index.html?c=250...

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