Recent Publications on : |  |
Epigenetic modifications induced by RGC-32 in colon cancer.
First described as a cell cycle activator, RGC-32 is both an activator and...
Direct Link | 4th November, 2009
| Department of Neurology, University of Maryland School of Medicine,
|
FXR Acetylation Is Normally Dynamically Regulated by p300 and SIRT1 but Constitutively Elevated in Metabolic Disease States.
The nuclear bile acid receptor FXR is critical for regulation of lipid and...
Direct Link | 4th November, 2009
| Department of Molecular and Integrative Physiology, University of
|
SIRT1-dependent Regulation of Chromatin and Transcription: Linking NAD(+) Metabolism and Signaling to the Control of Cellular Functions.
Sirtuins comprise a family of NAD(+)-dependent protein deacetylases and...
Direct Link | 3rd November, 2009
| Department of Molecular Biology and Genetics, Cornell University, Ithaca,
|
Effects of caloric restriction on SIRT1 expression and apoptosis of islet beta cells in type 2 diabetic rats.
Increasing evidence suggests that a restricted caloric intake extends the...
Direct Link | 31st October, 2009
| Department of Endocrinology, Changzhou no.2 People's Hospital, Nanjing
|
Early life nutrition influences thymic growth in male mice that may be related to the regulation of longevity.
Nutrition and growth rate during early life can influence later health and...
Direct Link | 31st October, 2009
|
|
Involvement of sirtuin 1 in airway inflammation and hyperresponsiveness of allergic airway disease.
BACKGROUND: Bronchial asthma is a chronic inflammatory disorder of the...
Direct Link | 30th October, 2009
| The Department of Internal Medicine, Jeonju, South Korea; The Research
|
Insulin/IGF-1 paradox of aging: Regulation via AKT/IKK/NF-kappaB signaling.
GH/insulin/IGF-1 signaling is a vital pathway e.g. in the regulation of...
Direct Link | 29th October, 2009
| Department of Neurology, Institute of Clinical Medicine, University of
|
| Nicotinamide phosphoribosyltransferase regulates cell survival through autophagy in cardiomyocytes.
| 27th October, 2009
| Department of Cell Biology and Molecular Medicine, Cardiovascular Research
|
Improving Insulin Sensitivity via Activation of PPAR-{gamma} Increases Telomerase Activity in the Heart of OLETF rats.
This study was conducted to examine telomere biology in terms of improving...
Direct Link | 27th October, 2009
| kyushu university.
|
Biological effects of calorie restriction: From soup to nuts.
Caloric restriction (CR), reduced protein, methionine, or tryptophan...
Direct Link | 27th October, 2009
| Department of Biochemistry, University of California, Riverside,
|
Polyploidy impairs human aortic endothelial cell function and is prevented by nicotinamide phosphoribosyltransferase.
Polyploid endothelial cells are found in aged and atherosclerotic...
Direct Link | 23rd October, 2009
| 1The University of Western Ontario.
|
Resveratrol is Not a Direct Activator of SIRT1 Enzyme Activity.
Resveratrol is a plant polyphenol capable of exerting beneficial metabolic...
Direct Link | 22nd October, 2009
| Department of Neuroscience, Amgen Inc., One Amgen Center Drive, Thousand
|
E-cadherin transcriptional down-regulation by epigenetic and microRNA-200 family alterations is related to mesenchymal and drug-resistant phenotypes in human breast cancer cells.
The conversion of early stage tumors into invasive malignancies with an...
Direct Link | 20th October, 2009
| Division of Biochemical Toxicology, National Center for Toxicological
|
Red wine decreases asymmetric dimethylarginine via SIRT1 induction in human endothelial cells.
To investigate the effect of three red wines (RWs) from different growing...
Direct Link | 17th October, 2009
| Institute of Clinical Pharmacology, Faculty of Medicine, Otto-von-Guericke
|
HIPK2 modulates p53 activity towards pro-apoptotic transcription.
BACKGROUND: Activation of p53-mediated gene transcription is a critical...
Direct Link | 16th October, 2009
| Department of Experimental Oncology, Molecular Oncogenesis Laboratory,
|
