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TARDBP
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18309045 |
study identified neighboring mutations in a highly conserved region of TARDBP in sporadic and familial amyotrophic lateral sclerosis (ALS) cases; evidence suggests a pathophysiological link between TDP-43 and ALS |
| 18288693 |
Sequencing of the TDP-43 gene led to the identification of a novel missense mutation, Ala-315-Thr, which segregates with all affected members of an autosomal dominant motor neuron disease family. |
| 17614162 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18068872 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17981595 |
TDP-43 has a role in transcription and splicing regulation and may be involved in other cellular processes such as microRNA biogenesis, apoptosis, and cell division [review] |
| 17492294 |
TDP-43 proteinopathy is the common pathologic substrate linking frontotemporal lobar degeneration and amyotrophic lateral sclerosis. |
| 17569066 |
TDP-43 immunoreactivity was detected in the hypoglossal nucleus in all cases of amyotrophic lateral sclerosis, all cases of frontotemporal lobar degeneration and some of cases of primary lateral sclerosis (PLS). |
| 16157593 |
the C-terminal region of TDP-43 is capable of binding directly to several proteins of the heterogeneous nuclear ribonucleoprotein (hnRNP) family with well known splicing inhibitory activity, in particular, hnRNP A2/B1 and hnRNP A1 |
| 12361981 |
Through the analysis of TDP, a protein functional in both transcriptional repression and alternative splicing, we have identified a new category of nuclear bodies within which the TDP molecules reside. |
| 17023659 |
findings showed that TDP-43 is the major disease protein in frontotemporal lobar degeneration and amyotrophic lateral sclerosis; it was recovered only from affected central nervous system regions | →View more information from publications. |
Recent Publications on TARDBP: |  |
A novel TARDBP mutation in an Australian amyotrophic lateral sclerosis kindred.
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder... | 30th October, 2009
| Northcott Neuroscience Laboratory, ANZAC Research Institute, Concord
| J Neurol Neurosurg Psychiatry. 2009 Nov;80(11):1286-8.
DOI Direct Link |
TARDBP in amyotrophic lateral sclerosis: identification of a novel variant but absence of copy number variation.
BACKGROUND: Mutations in the gene encoding TDP-43 have been identified in... | 30th October, 2009
| University of Oxford, MRC Functional Genetics Unit, Department of
| J Neurol Neurosurg Psychiatry. 2009 Nov;80(11):1283-5.
DOI Direct Link |
Mutations in TDP-43 link glycine-rich domain functions to amyotrophic lateral sclerosis.
Amyotrophic lateral sclerosis (ALS) is the most common adult motor neuron... | 8th October, 2009
| Department of Pathology and Laboratory Medicine, Center for
| Hum Mol Genet. 2009 Oct 15;18(R2):R156-62.
DOI Direct Link |
Biomarkers in amyotrophic lateral sclerosis: facts and future horizons.
The only specific marker of sporadic amyotrophic lateral sclerosis (ALS)... | 3rd October, 2009
| Assistance Publique - Hopitaux de Paris, Federation des Maladies du
| Mol Diagn Ther. 2009;13(2):115-25. doi: 10.2165/01250444-200913020-00005.
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Absence of TARDBP gene mutations in an italian series of patients with frontotemporal lobar degeneration.
BACKGROUND/AIM: Recent studies showed that TAR DNA-binding protein 43... | 30th September, 2009
| Neurology II, Department of Neuroscience, University of Turin, Turin,
| Dement Geriatr Cogn Disord. 2009;28(3):239-43. Epub 2009 Sep 25.
DOI Direct Link |
→View more research publications. |
TARDBP results (if any) from reagent suppliers | 
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TARDBP antibody (ab50930) | Abcam
Rabbit polyclonal to TARDBP. HIV1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a
chromosomally ...
http://www.abcam.com/TARDBP-antibody-ab50930.html...
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TARDBP (41-7.1) Antibody sc-100871
TARDBP (41-7.1): sc-100871. Immunofluorescence staining of paraformaldehyde- fixed HeLa cells showing nuclear localization. ...
http://www.scbt.com/datasheet-100871-tardbp-41-7-1-antibody....
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TARDBP antibodies: Neuroscience > Neurology process ...
TARDBP antibodies. ... TARDBP antibody. WB, ICC/IF, IHC-Fr. Images · Customer Abreviews: 5 stars (out of 5). Rabbit polyclonal ...
http://www.abcam.com/index.html?t=169962&pt=1&c=1047&ei=&mu=...
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TARDBP (P-24) Antibody sc-102127
TARDBP (P-24): sc-102127. Immuno-peroxidase staining of formalin fixed, ... Western blot analysis of TARDBP expression in Jurkat whole cell lysate. ...
http://www.scbt.com/datasheet-102127-tardbp-p-24-antibody.ht...
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TARDBP protein, TAR DNA-binding protein 43 recombinant protein
Buy quality TARDBP protein (e coli), TARDBP, TAR DNA-binding protein 43 recombinant protein, (ms sds elisa western blot). TDP-43; TAR DNA binding
protein, ...
http://www.genwaybio.com/product_info.php?products_id=5112...
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TARDBP Antibody / TARDBP Antibodies
TARDBP Antibody / TARDBP Antibodies. ... TARDBP specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-tardbp.html...
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TARDBP proteins and peptides: Microbiology > Organism > Virus ...
TARDBP proteins and peptides. ... TARDBP protein (Human). WB, Inhib, ELISA. Images · ab40288 · TARDBP protein (T7 Tag). SDS-PAGE ...
http://www.abcam.com/index.html?t=169962&pt=2&c=677&ei=&mu=r...
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