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ABCB9


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Gene DB Home
Symbol:ABCB9
Name(s):ATP-binding cassette, sub-family B (MDR/TAP), member 9
Type:protein-coding
Organism:Homo sapiens
Synonyms:EST122234, KIAA1520, TAPL
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17977821 the TAPL-specific translocation of peptides into isolated lysosomes strictly requires ATP hydrolysis
18175933 The ATP-binding of TAPL required Mg(2+), and was observed at neutral pH. Chemical cross-linking experiments suggested that TAPL forms a homodimer in the membrane and under the solubilized conditions.
15863492 is part of the peptide-loading complex in the classic route of antigen processing via major histocompatibility complex class I molecules
16554024 These findings suggest that the transport activity of hTAPL is important for conferring high valinomycin-sensitive phenotype to yeast.

Recent Publications on ABCB9:

Pubmed Logo
Normal formation of a subset of intestinal granules in Caenorhabditis elegans requires ATP-binding cassette transporters HAF-4 and HAF-9, which are highly homologous to human lysosomal peptide transporter TAP-like.
TAP-like (TAPL; ABCB9) is a half-type ATP-binding cassette (ABC)...
22nd September, 2009
Department of Molecular Biology and Biochemistry, Graduate School of Mol Biol Cell. 2009 Jun;20(12):2979-90. Epub 2009 Apr 29.
DOI Direct Link
Functional dissection of transmembrane domains of human TAP-like (ABCB9).
An ABC transporter, TAP-Like (TAPL), was dissected into its amino-terminal...
17th December, 2008
Laboratory of Biochemistry and Molecular Biology, Graduate School of Biochem Biophys Res Commun. 2008 Dec 19;377(3):847-51. Epub 2008 Oct 24.
DOI Direct Link
Peptide specificity and lipid activation of the lysosomal transport complex ABCB9 (TAPL).
The lysosomal ABC transporter associated with antigen processing-like...
26th July, 2008
Institute of Biochemistry, Biocenter, Goethe-University Frankfurt, J Biol Chem. 2008 Jun 20;283(25):17083-91. Epub 2008 Apr 22.
DOI Direct Link
Identification of a lysosomal peptide transport system induced during dendritic cell development.
The delivery of protein fragments to major histocompatibility complex...
5th March, 2008
Institute of Biochemistry, Biocenter, Goethe-University Frankfurt, J Biol Chem. 2007 Dec 28;282(52):37836-43. Epub 2007 Oct 31.
DOI Direct Link
Biochemical characterization of transporter associated with antigen processing (TAP)-like (ABCB9) expressed in insect cells.
The ATP-binding cassette (ABC) transporter, transporter associated with...
7th February, 2008
Laboratory of Biochemistry and Molecular Biology, Graduate School of Biol Pharm Bull. 2008 Jan;31(1):1-5.

View more research publications.

Patents:

Patents logo
US Patent No.Title
7175999 Polynucleotide and polypeptide fat metabolism regulators and uses thereof
6830913 ABCB9 transporter and uses thereof

ABCB9 results (if any) from reagent suppliers

Google CSE Logo
ABCB9 Antibody ABCB9 / TAPL
ABCB9 antibody was raised against a synthetic peptide of ABCB9.,
http://www.prosci-inc.com/shop/catalog1/ABCB9-Antibody-p-261...

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ABCB9 (K-16) Antibody sc-46746
goat polyclonal IgG, 200µg/ml; epitope mapping within an internal region of ABCB9 of human origin; recommended for detection of ABCB9 isoforms 1, 2, 3, ...
http://www.scbt.com/datasheet-46746-abcb9-k-16-antibody.html...

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ABCB9 peptide (754-766) (ab45490) | Abcam
ABCB9 peptide (754-766). The membrane associated protein encoded by this gene is a member of the superfamily of ATP binding cassette (ABC) transporters.
http://www.abcam.com/ABCB9-peptide-754-766-ab45490.html...

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ABC Antibody / ABC Antibodies
ABCB9 (C-15) Antibody, sc-46745, goat IgG, C-terminus (h), WB, IP, IF, ... ABCB9 (K-16) Antibody, sc-46746, goat IgG, Internal (h), WB, IF, ELISA, m, r, h ...
http://www.scbt.com/table-abc.html...

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Cancer Antibodies :: Page 1
ABCB5 Antibody, 46-620, H, E, WB, ABCB5. ABCB9 Antibody, 45-180, H, E, IHC, ABCB9 / TAPL. ABCC4 Antibody, 45-181, H, M, R, E, WB, IHC, ABCC4 / MRP4 ...
http://www.prosci-inc.com/shop/catalog1/Cancer-Antibodies-p-...

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ABCB9 (C-13) Antibody sc-46744
ABCB9 (C-13) 抗体sc-46744 ABCB9 (C-13) Antibody sc-46744.
http://www.scbt.com/zh/datasheet-46744-abcb9-c-13-antibody.h...

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Primary antibodies | Abcam
ABCB9 antibody. IP, WB. Images. Rabbit polyclonal. Reacts with: Hu, Ms. ab39273 · ABCB9 antibody. WB. Images · Customer Abreviews: 3 stars (out of 5) ...
http://www.abcam.com/index.html?pageconfig=catalog_byproduct...

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