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HEY1
| Symbol: | HEY1 | | Name(s): | hairy/enhancer-of-split related with YRPW motif 1 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | CHF2, HERP2, HESR1, HRT-1, MGC1274, OAF1 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17496152 |
Declines in HEY1 are associated with pulmonary fibrosis and hypertension. |
| 17028039 |
HESR1 seems to inhibit the vessel-promoting effects of VEGF, shift endothelial cells from a proliferative state to a quiescent state, and restore normal vessel structures. |
| 12453432 |
HESR-1 may be involved in the phenotypic changes that characterize the progression from EC proliferation and migration to network formation and quiescence |
| 15314183 |
These results define a novel regulatory pathway linking the transcription factors c-Jun, HERP2, and GATA-1. |
| 15684393 |
Hey1 is excluded from the nucleus in most human prostate cancers, raising the possibility that an abnormal Hey1 subcellular distribution may have a role in the aberrant hormonal responses observed in prostate cancer. |
| 15749835 |
Hesr1 down-regulates DAT1 gene expression with the 3' non-coding region, the negative regulations depend on bHLH and the Orange domain of the molecule, but not the YRPW motif. |
| 15680351 |
A similar gene in mouse regulates cardiovascular development |
Recent Publications on HEY1: |  |
Ubiquitous overexpression of Hey1 transcription factor leads to osteopenia and chondrocyte hypertrophy in bone.
The transcription factor Hey1, a known Notch target gene of the HES... | 28th October, 2009
| Musculoskeletal Disease Area, Novartis Institutes for BioMedical Research,
| Bone. 2009 Oct 24.
DOI Direct Link |
NK-like homeodomain proteins activate NOTCH3-signaling in leukemic T-cells.
BACKGROUND: Homeodomain proteins control fundamental cellular processes in... | 20th October, 2009
| Dept. of Human and Animal Cell Lines, DSMZ - German Collection of
| BMC Cancer. 2009 Oct 19;9:371.
DOI Direct Link |
Notch ligand-dependent gene expression in human endometrial stromal cells.
The purpose of this study is to investigate the expression patterns and... | 14th October, 2009
| Dept. of OB/GYN and Reproductive Medicine, School of Medicine, Stony Brook
| Biochem Biophys Res Commun. 2009 Oct 23;388(3):479-82. Epub 2009 Jul 14.
DOI Direct Link |
Cancer genomics identifies regulatory gene networks associated with the transition from dysplasia to advanced lung adenocarcinomas induced by c-Raf-1.
BACKGROUND: Lung cancer is a leading cause of cancer morbidity. To improve... | 9th October, 2009
| Department of Molecular Medicine, Fraunhofer Institute of Toxicology and
| PLoS One. 2009 Oct 8;4(10):e7315.
DOI Direct Link |
HEY1 Leu94Met gene polymorphism dramatically modifies its biological functions.
The hairy/enhancer-of-split related with YRPW motif 1 (HEY1) is a member... | 6th October, 2009
| Department of Cancer Biology, Instituto de Investigaciones Biomedicas,
| Oncogene. 2009 Oct 5.
DOI Direct Link |
→View more research publications. |
HEY1 results (if any) from reagent suppliers | 
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HEY1 antibody (ab22614) | Abcam
Rabbit polyclonal to HEY1. Hairy/enhancer of split-related proteins, such as HEY1, are basic helix-loop-helix (bHLH) transcription factors implicated in ...
http://www.abcam.com/HEY1-antibody-ab22614.html...
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HEY1 monoclonal antibody (M09)
HEY1 (NP_036390, 121 a.a. ~ 221 a.a) partial recombinant protein with GST tag. ... Detection limit for recombinant GST tagged HEY1 is approximately 0.1ng/ml
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http://www.abgent.com/products/catalog_no/AT2358a_HEY1_monoc...
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The Abcam catalog
HEY1 antibodies. ... Image Abreview Publication. ab22614 · HEY1 antibody. IHC-P, WB. Images · Specific publication references. Rabbit polyclonal ...
http://www.abcam.com/index.html?t=112860&pt=1&c=3395...
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HRT1 (C-20) Antibody sc-16424
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, HEY1, 23462, 8q21.13, NM_012258 ...
http://www.scbt.com/datasheet-16424-hrt1-c-20-antibody.html...
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HEY1 proteins and peptides: Chromatin and Nuclear Signaling ...
HEY1 proteins and peptides. ... Applications (see key) & Reactivity (see key). Image Abreview Publication. ab40321 · HEY1 protein (His tag). SDS-PAGE ...
http://www.abcam.com/index.html?t=112860&pt=2&c=3395&ei=&mu=...
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Antibody Products - IgG Polyclonal Antibodies - GenWay
HEY1; CHF2; HESR1; OAF1; HERP2 - Hairy and enhancer of split-related protein 1; HESR-1; Cardiovascular helix-loop-helix factor 2; HES-related repressor ...
http://www.genwaybio.com/all_polyclonal_antibodies.php?fl=H...
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Abgent - Transcription and Regulation Antibodies ...
AT2357aNEW, HEY1 monoclonal antibody (M07), ELISA,S-ELISA, H. AT2358aNEW, HEY1 monoclonal antibody (M09), ELISA,S-ELISA,WB-Re, H ...
http://www.abgent.com/products/category/nuclear_signaling/tr...
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