Recent Publications on : |  |
Ubiquitous overexpression of Hey1 transcription factor leads to osteopenia and chondrocyte hypertrophy in bone.
The transcription factor Hey1, a known Notch target gene of the HES...
Direct Link | 28th October, 2009
| Musculoskeletal Disease Area, Novartis Institutes for BioMedical Research,
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NK-like homeodomain proteins activate NOTCH3-signaling in leukemic T-cells.
BACKGROUND: Homeodomain proteins control fundamental cellular processes in...
Direct Link | 20th October, 2009
| Dept. of Human and Animal Cell Lines, DSMZ - German Collection of
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Notch ligand-dependent gene expression in human endometrial stromal cells.
The purpose of this study is to investigate the expression patterns and...
Direct Link | 14th October, 2009
| Dept. of OB/GYN and Reproductive Medicine, School of Medicine, Stony Brook
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Cancer genomics identifies regulatory gene networks associated with the transition from dysplasia to advanced lung adenocarcinomas induced by c-Raf-1.
BACKGROUND: Lung cancer is a leading cause of cancer morbidity. To improve...
Direct Link | 9th October, 2009
| Department of Molecular Medicine, Fraunhofer Institute of Toxicology and
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HEY1 Leu94Met gene polymorphism dramatically modifies its biological functions.
The hairy/enhancer-of-split related with YRPW motif 1 (HEY1) is a member...
Direct Link | 6th October, 2009
| Department of Cancer Biology, Instituto de Investigaciones Biomedicas,
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Dissection of the transformation of primary human hematopoietic cells by the oncogene NUP98-HOXA9.
NUP98-HOXA9 is the prototype of a group of oncoproteins associated with...
Direct Link | 22nd August, 2009
| Department of Pathology and Immunology, Washington University School of
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| Three-dimensional culture using a radial flow bioreactor induces matrix metalloprotease 7-mediated EMT-like process in tumor cells via TGFbeta1/Smad pathway.
| 4th August, 2009
| Department of Biochemistry, Jikei University School of Medicine,
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HeyL regulates the number of TrkC neurons in dorsal root ganglia.
The basic-helix-loop-helix transcription factor HeyL is expressed at high...
Direct Link | 28th July, 2009
| Department of Neurology, Northwestern University's Feinberg School of
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New insights into BMP-7 mediated osteoblastic differentiation of primary human mesenchymal stem cells.
Bone Morphogenetic Proteins (BMPs) are members of the TGF-beta superfamily...
Direct Link | 23rd July, 2009
| Stryker Biotech, Hopkinton, MA 01748, USA.
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Multiple mechanisms induce ectopic expression of LYL1 in subsets of T-ALL cell lines.
Basic helix-loop-helix (bHLH) transcription factors are essential for...
Direct Link | 18th July, 2009
| Dept. of Human and Animal Cell Lines, DSMZ - German Collection of
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Inhibition of Notch pathway prevents osteosarcoma growth by cell cycle regulation.
The study shows constitutive activation of the Notch pathway in various...
Direct Link | 3rd July, 2009
| Department of Orthopaedic Surgery, Graduate School of Medical and Dental
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Gene expression profiling provides insights into the pathways involved in solid pseudopapillary neoplasm of the pancreas.
Solid-pseudopapillary neoplasms (SPNs) are rare human pancreatic neoplasms...
Direct Link | 25th June, 2009
| Institut Cochin, Universite Paris Descartes, CNRS (UMR 8104), Paris,
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Kaposi's sarcoma-associated herpesvirus RTA promotes degradation of the Hey1 repressor protein through the ubiquitin proteasome pathway.
The Kaposi's sarcoma-associated herpesvirus (KSHV) replication and...
Direct Link | 19th June, 2009
| Institute of Molecular and Cellular Biology, Faculty of Biological
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On the role of FOX transcription factors in adipocyte differentiation and insulin-stimulated glucose uptake.
In this study, we explore the effects of several FOX and mutant FOX...
Direct Link | 19th June, 2009
| Departments of Molecular & Integrative Physiology and Internal Medicine,
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Notch signaling during chondrogenesis of human bone marrow stem cells.
Notch signaling is an important mechanism involved in early development...
Direct Link | 2nd May, 2009
| North West Embryonic Stem Cell Centre, Faculty of Life Sciences,
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