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HEY2
| Symbol: | HEY2 | | Name(s): | hairy/enhancer-of-split related with YRPW motif 2 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | CHF1, GRL, HERP1, HESR2, HRT2, MGC10720 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 15643620 |
Observational study of gene-disease association. (HuGE Navigator) |
| 15389319 |
To clarify the role of HEY2 in human CHD and AGS, we screened by direct sequencing 23 children with CHD and 38 patients diagnosed with AGS. Mutation of HEY2 is not a major contributing factor. |
| 12535671 |
These results indicate that the molecular association between HES1-, HEY2- and SIRT1-related proteins is conserved among metazoans, from Drosophila to human, and suggest that the Sir2-bHLH interaction also plays important roles in human cells. |
| 16293227 |
CHF1/Hey2 may affect smooth-muscle cell phenotype through an important transcriptional mechanism |
| 16329098 |
This result suggests a possible role of HEY2 in the regulation of ventricular septation in humans. |
| 16151017 |
HERP1 may play a role in promoting the phenotypic modulation of vascular smooth muscle cells during vascular injury and atherosclerotic process by interfering with SRF binding to CArG-box |
| 15680351 |
A similar gene in mouse regulates cardiovascular development |
Recent Publications on HEY2: |  |
Novel features of boundary cap cells revealed by the analysis of newly identified molecular markers.
Neural crest (NC) cells are a multipotent, highly migratory cell... | 31st October, 2009
| INSERM, CNRS, IFR36, Plate-forme Transcriptome, 46 rue d'Ulm, 75230 Paris
| Glia. 2009 Oct;57(13):1450-7.
DOI Direct Link |
4q32-q35 and 6q16-q22 are valuable candidate regions for split hand/foot malformation.
On the basis of the Human Cytogenetic Database, a computerized catalog of... | 9th October, 2009
| Institute of Medical Genetics, University of Zurich, Schwerzenbach,
| Eur J Hum Genet. 2009 Aug;17(8):1086-91. Epub 2009 Feb 18.
DOI Direct Link |
HeyL regulates the number of TrkC neurons in dorsal root ganglia.
The basic-helix-loop-helix transcription factor HeyL is expressed at high... | 28th July, 2009
| Department of Neurology, Northwestern University's Feinberg School of
| Dev Biol. 2009 Oct 1;334(1):142-51. Epub 2009 Jul 22.
DOI Direct Link |
Inhibition of Notch pathway prevents osteosarcoma growth by cell cycle regulation.
The study shows constitutive activation of the Notch pathway in various... | 3rd July, 2009
| Department of Orthopaedic Surgery, Graduate School of Medical and Dental
| Br J Cancer. 2009 Jun 16;100(12):1957-65. Epub 2009 May 19.
DOI Direct Link |
Smooth muscle Notch1 mediates neointimal formation after vascular injury.
BACKGROUND: Notch1 regulates binary cell fate determination and is... | 25th June, 2009
| Vascular Medicine Research, Brigham and Women's Hospital and Harvard
| Circulation. 2009 May 26;119(20):2686-92. Epub 2009 May 11.
DOI Direct Link |
→View more research publications. |
HEY2 results (if any) from reagent suppliers | 
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HEY2 proteins and peptides: Stem Cells > Signaling Pathways ...
HEY2 proteins and peptides. ... HEY2 proteins and peptides. Code. Name. Applications (see key) & Reactivity (see key). Image Abreview Publication ...
http://www.abcam.com/index.html?t=125342&pt=2&c=3514&ei=&mu=...
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HRT2 (H-95) Antibody sc-28747
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, HEY2, 23493, 6q22.31, NM_012259 ...
http://www.scbt.com/datasheet-28747-hrt2-h-95-antibody.html...
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HEY2 antibodies: Cardiovascular > Heart > Cardiogenesis ...
HEY2 antibodies. ... HEY2 antibody. WB, ELISA. Images. Rabbit polyclonal. Reacts with: Hu, Ms. Terms and conditions · Legal · Privacy policy ...
http://www.abcam.com/index.html?t=125342&pt=1&c=4445&ei=&mu=...
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Purified Anti-SIRT1 Antibody - BioLegend
Interaction: p53, E1A binding protein p300, HEY2, NF-kB3, Transcription factor HES-1, Forkhead box protein O3A, and PML. ...
http://www.biolegend.com/purified-anti-sirt1-antibody-4385.h...
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FOXC2 antibody - ChIP Grade (ab5060) | Abcam
Hayashi H & Kume T Foxc transcription factors directly regulate Dll4 and Hey2 expression by interacting with the VEGF-Notch signaling pathways in ...
http://www.abcam.com/FOXC2-antibody-ChIP-Grade-ab5060.html...
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BioVendor R&D - Antibodies \ HES1(Hairy and enhancer of split 1 ...
... the embryonic stem cellspecific network of transcription factors, and that HES1, HES5, HEY1, HEY2 and HEYL are target genes of Notch signaling pathway. ...
http://www.biovendor.com/product/antibodies/hes1-hairy-and-e...
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HRT2 (A-20) Antibody sc-16446
Humain, HEY2, 23493, 6q22.31, NM_012259 · Q9UBP5 · 604674. Souris, Hey2, 15214, 10 A4, Q9QUS4, Non disponible. Produits disponibles ...
http://www.scbt.com/fr/datasheet-16446-hrt2-a-20-antibody.ht...
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