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MACF1
| Symbol: | MACF1 | | Name(s): | microtubule-actin crosslinking factor 1 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | ABP620, ACF7, FLJ45612, FLJ46776, KIAA0465, KIAA1251, MACF, OFC4 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 16076900 |
In two lung cell lines, MACF1b was chiefly localized to the Golgi complex. The domain of MACF1b that targets it to the Golgi was found at the N-terminal part of the region that contains the plakin repeats. |
| 15265687 |
p230, through its interaction with MACF1, provides the molecular link for transport of GPI-anchored proteins along the microtubule and actin cytoskeleton from the TGN to the cell periphery. |
Recent Publications on MACF1: |  |
Plakins in striated muscle.
Striated muscle cells contain numerous architectural proteins that... | 22nd September, 2009
| Department of Biology, Laurentian University, Sudbury, Ontario, Canada.
| Muscle Nerve. 2009 Sep 18.
DOI Direct Link |
Mouse ACF7 and drosophila short stop modulate filopodia formation and microtubule organisation during neuronal growth.
Spectraplakins are large actin-microtubule linker molecules implicated in... | 18th September, 2009
| Faculty of Life Sciences, The University of Manchester, Michael Smith
| J Cell Sci. 2009 Jul 15;122(Pt 14):2534-42.
DOI Direct Link |
Large gradient high magnetic field affects the association of MACF1 with actin and microtubule cytoskeleton.
The intense inhomogeneous magnetic fields acting on the diamagnetic... | 29th May, 2009
| Key Laboratory for Space Biosciences & Biotechnology, Institute of Special
| Bioelectromagnetics. 2009 Oct;30(7):545-55.
DOI Direct Link |
ACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activity.
Coordinated interactions between microtubule (MT) and actin cytoskeletons... | 31st October, 2008
| Howard Hughes Medical Institute and Laboratory of Mammalian Cell Biology
| Cell. 2008 Oct 3;135(1):137-48.
DOI Direct Link |
A gene-trap strategy identifies quiescence-induced genes in synchronized myoblasts.
Cellular quiescence is characterized not only by reduced mitotic and... | 22nd August, 2008
| Centre for Cellular and Molecular Biology, Hyderabad, India.
| J Biosci. 2008 Mar;33(1):27-44.
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→View more research publications. |
MACF1 results (if any) from reagent suppliers | 
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MACF1 (H-146) Antibody sc-68428
rabbit polyclonal IgG, 200µg/ml; epitope corresponding to amino acids 465-610 mapping near the N-terminus of MACF1, isoform 1 of human origin ...
http://www.scbt.com/datasheet-68428-macf1-h-146-antibody.htm...
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MACF1 monoclonal antibody (M01)
MACF1 (AAH07330, 1 a.a. ~ 95 a.a) partial recombinant protein with GST tag. ... Detection limit for recombinant GST tagged MACF1 is approximately 1ng/ml as ...
http://www.abgent.com/products/catalog_no/AT2757a_MACF1_mono...
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MACfF Antibody / MACF Antibodies
MACF1 (M-244) Antibody, sc-68430, rabbit IgG, 1997-2240 (m), WB, IP, IF, ELISA, m, r. MACF1-4 (H-220) Antibody, sc-68429, rabbit IgG, 1561-1780 (h), WB, IP, ...
http://www.scbt.com/table-macf.html...
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Abgent - Cell and Structure Antibodies - Cell_structure
AP7605cNEW, LUM Antibody (Center), WB, E, H. AP7605aNEW, LUM Antibody (N-term), WB, E, H, M. AT2757a, MACF1 monoclonal antibody (M01), ELISA,S-ELISA, H ...
http://www.abgent.com/products/category/cell_function/cell_s...
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MACF1-4 (H-220) Antibody sc-68429
rabbit polyclonal IgG, 200µg/ml; epitope corresponding to amino acids 1561-1780 mapping within an internal region of MACF1, isoform 4 of human origin ...
http://www.scbt.com/ko/datasheet-68429-macf1-4-h-220-antibod...
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Imgenex citations of : IMG-800 (pSuppressorNeo)
14 Aug 2006 ... The role of microtubule actin cross-linking factor 1 (MACF1) in the Wnt signaling pathway. Hui-Jye Chen, Chung-Ming Lin, Chyuan-Sheng Lin, ...
http://www.imgenex.com/citations_details.php?name=804...
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