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FOS


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Symbol:FOS
Name(s):v-fos FBJ murine osteosarcoma viral oncogene homolog
Type:protein-coding
Organism:Homo sapiens
Synonyms:AP-1, C-FOS
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17495958 Coordinated down- and up-regulation of the various AP-1 subunits in the course of epidermal wound healing is important for its undisturbed progress, putatively by influencing inflammation and cell-cell communication.
17639289 Ras/MAPK cascade acts as the upstream signaling for AP-1 activation and IL-8 expression in toxin A-stimulated intestinal epithelial cells.
14727154 Observational study of gene-disease association. (HuGE Navigator)
17926144 c-Fos may undergo cell cycle dependent phosphorylation, in which some kinases including Aurora-A play a role in catalyzing the post translational modification of c-Fos.
18032824 VEGF, p-IkappaB-alpha, NF-kappaB, c-FOS, p-c-JUN, EGF-R and COX-2 were expressed in stromal myofibroblasts surrounding colon adenocarcinomas in the majority of cases.
17681951 Dimerization with the Jun proteins inhibits c-Fos nuclear exit.
17549045 In the paraventricular nucleus anandamide and N-arachidonoyl-serotonin increased significantly c-Fos expression. In the arcuate nucleus only OMDM-1 increased c-Fos expression.
17636030 Amino acid residues required for physical and cooperative transcriptional interaction of STAT3 and AP-1 proteins c-Jun and c-Fos.
17915561 During mitosis, HSF2 is bound to the HSE promoter elements of other heat shock genes, including hsp90 and hsp27, and the proto-oncogene c-fos. The presence of HSF2 is important for expression of these genes.
17606925 c-fos expression in the medial geniculate body triggered by cortical activation is elicited via a direct corticothalamic pathway, not by the pathway through the thalamic reticular nucleus.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDHuman DNA sequence from clone RP5-1099D15 on chromosome 20 Contains the 3' end of a novel gene, the JAG1 gene encoding Jagged 1, a pseudogene aimilar to DNAJ protein, a CpG island, ESTs, STSs and GSSs.v-fos FBJ murine osteosarcoma viral oncogene homologc-Fos interacts with Jagged1 promoter.-Pubmed
HPRDB-cell CLL/lymphoma 3v-fos FBJ murine osteosarcoma viral oncogene homolog--Pubmed
HPRDB-cell CLL/lymphoma 3v-fos FBJ murine osteosarcoma viral oncogene homolog--Pubmed
HPRDRunt related transcription factor 2v-fos FBJ murine osteosarcoma viral oncogene homolog--Pubmed
HPRDrunt-related transcription factor 2c-Fos--Pubmed
HPRDCBFA2v-fos FBJ murine osteosarcoma viral oncogene homolog--Pubmed
HPRDrunt-related transcription factor 1 isoform AML1cc-Fos--Pubmed
HPRDCCAAT/enhancer binding protein gammav-fos FBJ murine osteosarcoma viral oncogene homolog--Pubmed
HPRDCCAAT/enhancer binding protein gammav-fos FBJ murine osteosarcoma viral oncogene homolog--Pubmed
HPRDActivating transcription factor 2v-fos FBJ murine osteosarcoma viral oncogene homolog--Pubmed

Recent Publications on FOS:

Pubmed Logo
Dietary fructooligosaccharides and potential benefits on health.
Fructooligosaccharides (FOS) are oligosaccharides that occur naturally in...
2nd February, 2010
Department of Physiology, Faculty of Biology, University of Murcia, Spain, J Physiol Biochem. 2009 Sep;65(3):315-28.
DOI Direct Link
Identification of the early VIP-regulated transcriptome and its associated, interactome in resting and activated murine CD4 T cells.
More than 40 years after the discovery of vasoactive intestinal peptide...
2nd February, 2010
Department of Chemistry and Molecular Biology, North Dakota State Mol Immunol. 2010 Jan 29.
DOI Direct Link
Central litorin injection is associated with primary anorexigenic effects that coincide with activation of the magnocellular division of the paraventricular nucleus.
The central mechanism that mediates litorin-induced satiety is poorly...
2nd February, 2010
Department of Biology (6931), Radford University, Radford, VA 24142, USA. Neuropeptides. 2010 Jan 28.
DOI Direct Link
Y4 receptors and pancreatic polypeptide regulate food intake via hypothalamic orexin and brain-derived neurotropic factor dependent pathways.
Gut-derived peptides are known to regulate food intake by activating...
2nd February, 2010
Neuroscience Program, Garvan Institute of Medical Research, St. Vincent's Neuropeptides. 2010 Jan 27.
DOI Direct Link
The effect of MK-801 on motor activity and c-Fos protein expression in the brain of adolescent Wistar rats.
The changes that occur during adolescence have a profound impact on the...
2nd February, 2010
Department of Neurobiology Institute for Biological Research, University Brain Res. 2010 Jan 29.
DOI Direct Link

View more research publications.

Press Releases on FOS:

BioPortfolio Logo
Shire Submits Biologics License Application (BLA) for REPLAGAL(R) With the U.S. Food and Drug Administration (FDA) 22nd December, 2009

CAMBRIDGE, Massachusetts, December 22 /PRNewswire/ -- Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, today announced that it has submitted a BLA with the FDA

Shire Targets Fourth Quarter Filing of BLA for REPLAGAL(R) for Fabry Disease With U.S. FDA 21st October, 2009 Shire Plc

CAMBRIDGE, Massachusetts, October 21 /PRNewswire-FirstCall/ -- Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, announces plans to file a Biologics License

Frost & Sullivan European Digestive Health Ingredients Promising Ingredient of the Year Award Presented to Solvay for SOLACTIS(TM) 20th October, 2009 Frost & Sullivan

LONDON, Oct. 20 /PRNewswire/ --The 2009 Frost & Sullivan European Digestive Health Ingredients Promising Ingredient of the Year Award is presented to Solvay S.A. (Solvay

NanoBio to Announce Key Clinical and Preclinical Data in Nine Presentations at ICAAC/IDSA 2008 21st October, 2008 NanoBio Corporation, Interscience Conference on Antimicrobial Agents and Chemotherapy

ANN ARBOR, Mich., Oct. 21 /PRNewswire/ -- NanoBio Corporation announced today that it will present compelling new data in nine presentations that detail key milestones in its clinical and

PBM Products Introduces A-Soy(TM) Adult Nutritional Beverage for People Who are Lactose Intolerant, Cow's Milk Allergic, or Prefer a Vegetarian Diet 21st July, 2008 PBM Products, LLC

GORDONSVILLE, Va., July 21 /PRNewswire/ -- PBM Products, LLC, a leader in soy nutrition, announced today that it has introduced A-Soy, a soy adult nutritional beverage specially formulated for

BioNews Results for FOS

: RSS Logo
BioPortfolio Logo
Colon Cancer: Reports outline colon cancer study results from University of Queensland
NewsRX:  Dec 23 2009 5:26AM Matching: fos
The role of proto-oncogene Fra-1 in remodeling the tumor microenvironment in support of breast tumor cell inva
Nature:  Dec 22 2009 8:27PM Matching: fos

Clinical Trials:

Clinical Trials Logo
Idiopathic Reactive Hypoglycaemia and Treatment With Fructo-Oligosaccharide

Patents:

Patents logo
US Patent No.Title
7629144 Secreted epithelial colon stromal-1 molecules and uses thereof
7632923 Compositions capable of specifically binding particular human antigen presenting molecule/pathogen-derived antigen complexes and uses thereof
7632924 Antigen-binding polypeptides and their uses
7632932 Oligonucleotides comprising a ligand tethered to a modified or non-natural nucleobase
7632935 DNA encoding a mast cell-derived membrane protein

View more patents.

FOS results from Abnova

Google CSE Logo

Sponsored Results:

Abnova Logo
EGFR & FOS Protein Protein Interaction Antibody Pair
This protein protein interaction antibody pair set comes with two antibodies to detect the protein-protein interaction, one against the EGFR protein, and the other against the FOS protein for use in in situ Proximity Ligation Assay (in situ PLA™). See Publication Reference below.
Symbol: EGFR | FOS  Alias: ERBB, ERBB1, HER1, PIG61, mENA | AP-1, C-FOS
http://www.abnova.com/products/products_detail.asp?catalog_id=DI0275
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Abnova Logo
FOS monoclonal antibody (M06), clone 2C9
Mouse monoclonal antibody raised against a partial recombinant FOS.
Symbol: FOS  Alias: c-fos
http://www.abnova.com/products/products_detail.asp?catalog_id=H00002353-M06
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Abnova Logo
FOS Recombinant Protein (Q01)
FOS( NP_005243.1, 223 a.a. - 322 a.a.) partial recombinant protein with GST tag.
Symbol: FOS  Alias: c-fos
http://www.abnova.com/products/products_detail.asp?catalog_id=H00002353-Q01
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Abnova Logo
FOS monoclonal antibody (M05), clone 4D5
Mouse monoclonal antibody raised against a partial recombinant FOS.
Symbol: FOS  Alias: c-fos
http://www.abnova.com/products/products_detail.asp?catalog_id=H00002353-M05
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Abnova Logo
FOS polyclonal antibody
Rabbit polyclonal antibody raised against a synthetic peptides of FOS.
Symbol: FOS  Alias: AP-1, C-FOS
http://www.abnova.com/products/products_detail.asp?catalog_id=PAB0828
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Abnova Logo
FOS monoclonal antibody (M14), clone 2D11
Mouse monoclonal antibody raised against a full-length recombinant FOS.
Symbol: FOS  Alias: c-fos
http://www.abnova.com/products/products_detail.asp?catalog_id=H00002353-M14
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Search for FOS products at Abnova.

FOS results (if any) from reagent suppliers

Google CSE Logo
c-Fos Antibody #4384
c-Fos Antibody detects endogenous levels of total c-Fos protein. The antibody does not cross-react with other Fos proteins, including FosB, FRA1 and FRA2. ...
http://www.cellsignal.com/products/4384.html...

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c-Fos antibody (ab14285) | Abcam
Chicken polyclonal to c-Fos. The Fos gene family consists of 4 members: Fos, FosB, FosL1, and FosL2. These genes encode leucine zipper proteins that can ...
http://www.abcam.com/c-Fos-antibody-ab14285.html...

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c-Fos Antibody / c-Fos Antibodies
c-Fos Antibody / c-Fos Antibodies. ... c-Fos specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-c-fos.html...

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Anti-c-Fos Polyclonal Antibody
Polyclonal Antibody against c-Fos for use in Immunohistochemistry (Paraffin)
http://www.bioreagents.com/products/productDetails/productDe...

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Fos B siRNA (h) sc-35403
Fos B shRNA Plasmid (h): sc-35403-SH. Western blot analysis of human Fos B expression in Fos B transfected (A) and Fos B/Fos B shRNA Plasmid cotransfected
...
http://www.scbt.com/datasheet-35403-fos-b-sirna-h.html...

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Purified Anti-c-Fos Antibody - BioLegend
Purified Anti-c-Fos Antibody - The c-fos protein, also known as FBJ murine viral (v-fos) oncogene homolog , is a 62 kD cellular oncogene.
http://www.biolegend.com/purified-anti-c-fos-antibody-5443.h...

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c-Fos antibody (ab6167) | Abcam
At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this c-Fos antibody is on this
datasheet ...
http://www.abcam.com/c-Fos-antibody-ab6167.html...

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