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EDG7


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Symbol:EDG7
Name(s):endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7
Type:protein-coding
Organism:Homo sapiens
Synonyms:Edg-7, GPCR, HOFNH30, LP-A3, LPA3, LPAR3, RP4-678I3
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18006645 Lysophosphatidic acid receptor 3 may contribute to the pathogenesis of rheumatoid arthritis through the modulation of fibroblast-like synoviocyte migration and cytokine production.
17923111 expression of LPA-induced inflammatory response genes is mediated by LPA1 and LPA3
15292052 data suggest that endothelial differentiation gene EDG-7 regulates Lysophosphatidic acid(LPA)-mediated mesangial cell proliferation and suggest that EDG-7 and EDG-2 LPA receptors play a diverse role in mesangial cell proliferation
12123830 demonstrate that two biological fluids, blood plasma and seminal plasma, differentially activate LPA receptors
12668280 results suggested that lysophosphatidic acid (LPA) receptors LPA(2) and LPA(3) may be involved in VEGF expression mediated by LPA signals in human ovarian oncogenesis

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDguanine nucleotide binding protein, alpha inhibiting activity polypeptide 2endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7--Pubmed
HPRDguanine nucleotide binding protein, alpha inhibiting activity polypeptide 2endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7--Pubmed

Recent Publications on EDG7:

Pubmed Logo
Non-Edg family lysophosphatidic acid (LPA) receptors.
Lysophosphatidic acid (LPA; 1- or 2-acyl-sn-glycero-3-phosphate) is a...
16th June, 2009
Department of Biochemistry and Molecular Biology, Faculty of Medicine, The Prostaglandins Other Lipid Mediat. 2009 Sep;89(3-4):57-65. Epub 2009 Jun
DOI Direct Link
Full-length coding sequences, polymorphism and chromosomal localizations of the porcine EDG4 and EDG7 genes.
EDG4 and EDG7 are identified as cellular receptors for lysophosphatidic...
2nd June, 2009
Department of Veterinary Internal Medicine, College of Veterinary Mol Biol Rep. 2009 Apr;36(4):751-6. Epub 2008 Apr 1.
DOI Direct Link
The public health response to diabetes--two steps forward, one step back.
Lysophosphatidic acid (LPA; 1- or 2-acyl-sn-glycero-3-phosphate) is a...
21st April, 2009
Division of Diabetes Translation, Centers for Disease Control and JAMA. 2009 Apr 15;301(15):1596-8.
DOI Direct Link
Analysis of lysophosphatidic acid (LPA) receptor and LPA-induced endometrial prostaglandin-endoperoxide synthase 2 expression in the porcine uterus.
Lysophosphatidic acid (LPA), a simple phospholipid-derived mediator with...
1st April, 2009
Department of Biological Resources and Technology, Yonsei University, Endocrinology. 2008 Dec;149(12):6166-75. Epub 2008 Aug 14.
DOI Direct Link
[Expression and significance of Edg4 and Edg7 in the placentas of patients with hypertensive disorder complicating pregnancy]
OBJECTIVE: To study Edg4 and Edg7 expression in placenta of women with...
11th October, 2008
Department of Gynecology and Obstetrics, the First Affiliated Hospital of Zhonghua Fu Chan Ke Za Zhi. 2007 Jun;42(6):386-9.

View more research publications.

Patents:

Patents logo
US Patent No.Title
7572811 Immunosuppressant compounds and compositions
7099520 Image processing apparatus, image processing method, and program product for image processing
7063966 Chimeric G protein coupled receptors
7060697 Immunosuppressant compounds and compositions
7052850 Isolated human EDG-4 receptor

View more patents.

EDG7 results (if any) from reagent suppliers

Google CSE Logo
EDG-7 (K-19) Antibody sc-16090
EDG-7 shRNA (h) Lentiviral Particles, sc-37088-V, 200 µl ... Western blot analysis of EDG-7 expression in SK-N-MC whole cell lysate. Download ...
http://www.scbt.com/datasheet-16090-edg-7-k-19-antibody.html...

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Cayman Chemical | LPA3 Polyclonal Antibody | Description ...
5 Contos, J.J.A., Chun, J. The mouse lpA3/Edg7 lysophosphatidic acid receptor gene: genomic structure, chromosomal localization, and expression pattern. ...
http://www.caymanchem.com/app/template/Product.vm/catalog/10...

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EDG-7 (H-60) Antibody sc-25492
rabbit polyclonal IgG, 200 µg/ml; epitope corresponding to amino acids 294-353 mapping at the C-terminus of EDG-7 of human origin; recommended for detection
...
http://www.scbt.com/datasheet-25492-edg-7-h-60-antibody.html...

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EDG7 antibodies: Neuroscience > Neurotransmission > Receptors ...
EDG7 antibodies. ... Applications (see key) & Reactivity (see key). Image Abreview Publication. ab16456 · EDG7 antibody. WB. Rabbit polyclonal ...
http://www.abcam.com/index.html?t=82609&pt=1&c=459&ei=&mu=ra...

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EDG-7 Antibody / EDG-7 Antibodies
EDG-7 Antibody / EDG-7 Antibodies. ... EDG-7 specific siRNA, sHRNA Plasmid과 shRNA Lentiviral Particles gene silencers 도 제공합니다. ...
http://www.scbt.com/ko/table-edg-7.html...

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EDG-7 Functional Receptor Membrane Preparation
16 Sep 2002 ... Endothelial Cell Differentiation Gene-7 (EDG-7) belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. ...
http://www.exalpha.com/pdfs/X1275MP.pdf...

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EDG-7 siRNA (m) sc-37089
Click here for details. suitable control antibody: EDG-7 (K-19): sc-16090; sqRT- PCR Primer also available: EDG-7 (m)-PR: sc-37089-PR, 20 µl ...
http://www.scbt.com/ko/datasheet-37089-edg-7-sirna-m.html...

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