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AMACR


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Gene DB Home
Symbol:AMACR
Name(s):alpha-methylacyl-CoA racemase
Type:protein-coding
Organism:Homo sapiens
Synonyms:RACE
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
12438241 Observational study of gene-disease association. (HuGE Navigator)
17680641 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17683075 Observational study of gene-disease association. (HuGE Navigator)
17684125 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17683075 Our results confirm an initial report of association between the AMACR gene and the risk of familial prostate cancer.
17680641 AMACR gene variants were unrelated to prostate cancer overall in this study.
17684125 Variants in AMACR associated with advanced distal colorectal adenoma were identified and pointed to potential interactions with iburpofen use.
17222253 Expression in prostatic cancer shows a correlation with Gleason severity score.
16506014 Moderate to strong P504S expression in high-grade prostatic intraepithelial neoplasia of biopsy specimens is indicative of an associated adenocarcinoma.
17067752 Increase in AMACR expression is associated with prostate cancer

View more information from publications.

Recent Publications on AMACR:

Pubmed Logo
A Continuous Assay for alpha-Methylacyl-CoA Racemase (AMACR) Using Circular Dichroism.
a-Methylacyl-CoA racemase (AMACR) catalyzes the epimerization of (2R)- and...
27th October, 2009
Department of Biochemistry & Molecular Biology, Dalhousie University, Anal Biochem. 2009 Oct 22.
DOI Direct Link
Prostate carcinogenesis induced by N-methyl-N-nitrosourea (mnu) in gerbils: Histopathological diagnosis and potential invasiveness mediated by extracellular matrix components.
In the present study prostate lesions were induced in gerbils (Meriones...
13th October, 2009
Sao Paulo State University, Institute of Biosciences, Humanities and Exact Exp Mol Pathol. 2009 Oct 8.
DOI Direct Link
[Immunohistochemical algorithms in prostate diagnostics : What's new?]
Immunohistochemistry has become an indispensible tool in biopsy...
2nd October, 2009
Department Pathologie, Institut fur klinische Pathologie, Pathologe. 2009 Oct 2.
DOI Direct Link
Conversion of prostate cancer from hormone independency to dependency due to AMACR inhibition: involvement of increased AR expression and decreased IGF1 expression.
Androgen-independent prostate cancer eventually develops metastasis, and...
9th September, 2009
Department of Urology, Osaka Medical College, Takatsuki, Osaka 569-8686, Anticancer Res. 2009 Jul;29(7):2497-505.
Revisiting the immunophenotype of nephrogenic adenoma.
Nephrogenic adenoma (NA) is a rare benign lesion of the urinary tract....
5th September, 2009
Department of Pathology, CHU/Universite de Poitiers, Poitiers, France. Am J Surg Pathol. 2009 Nov;33(11):1654-8.
DOI Direct Link

View more research publications.

Press Releases on AMACR:

BioPortfolio Logo
MDS Analytical Technologies' Laser Capture Microdissection Helps Facilitate Discovery of Potential New Colon-Cancer Biomarker 4th February, 2009 MDS Inc.

SUNNYVALE, CA, Feb. 4 /PRNewswire-FirstCall/ - MDS Analytical Technologies, a leader in innovative solutions for drug discovery and life sciences research, today announced that its Arcturus(R)

Patents:

Patents logo
US Patent No.Title
7588890 Device for extracting biological molecules from tissue specimens and methods for preparing the same
7279281 Methods and kits for diagnosing or monitoring autoimmune and chronic inflammatory diseases
7332290 Dectection of AMACR cancer markers in urine
7374897 Enzyme cycling based assays for alpha-methylacyl-CoA racemase
7374902 Enzyme cycling based assays for alpha-methylacyl-CoA racemase

View more patents.

AMACR results (if any) from reagent suppliers

Google CSE Logo
AMACR antibody (ab12498) | Abcam
AMACR antibody - more information. Customer reviews (feedback) regarding AMACR antibody ... Contact Abcam with a Technical Enquiry about AMACR antibody ...
http://www.abcam.com/amacr-antibody-ab12498.html...

Thumbshot
AMACR Monoclonal Antibody alpha-methylacyl-CoA racemase
AMACR (alpha-methylacyl-CoA racemase) has been recently described as prostate cancer-specific gene that encodes a protein involved in the beta-oxidation of
...
http://www.prosci-inc.com/shop/catalog1/AMACR-Monoclonal-Ant...

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AMACR antibody, prediluted (ab15492) | Abcam
Rabbit polyclonal to AMACR, prediluted. AMARC has been recently described as prostate cancer-specific gene that encodes a protein involved in the ...
http://www.abcam.com/AMACR-antibody-prediluted-ab15492.html...

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p504S/ AMACR
Description: Alpha methylacyl-CoA-racemase (AMACR), also known as p504s is an enzyme involved in the metabolism of branched-chain fatty acids. p504s is ...
http://www.labvision.com/ab.cfm?first=AntiBody&second=9130...

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AMACR + p63 antibody [4A4 (p63)] - Cocktail of mouse monoclonal ...
Mouse monoclonal [4A4 (p63)] to AMACR + p63 - Cocktail of mouse monoclonal and rabbit polyclonal. AMACR has been recently described as a prostate cancer ...
http://www.abcam.com/AMACR-p63-antibody-4A4-p63-Cocktail-of-...

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Anti-AMACR Polyclonal Antibody
Polyclonal Antibody against AMACR for use in Immunohistochemistry (Paraffin)
http://www.bioreagents.com/products/productDetails/productDe...

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AMACR antibody [2A10F3] (ab63340) | Abcam
Mouse monoclonal [2A10F3] to AMACR. AMARC has been recently described as prostate cancer-specific gene that encodes a protein involved in the beta-
oxidation ...
http://www.abcam.com/AMACR-antibody-2A10F3-ab63340.html...

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