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DAPK2


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Symbol:DAPK2
Name(s):death-associated protein kinase 2
Type:protein-coding
Organism:Homo sapiens
Synonyms:DRP-1, MGC119312
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17347302 Results implicate a novel role for DAPK2 in the regulation of normal myelopoiesis.
12087472 gene expression in colorectal and gastric cancer silenced by DNA methylation and histone deacetylation
11839660 High frequency of promoter hypermethylation of the death-associated protein-kinase gene in nasopharyngeal carcinoma and its detection in the peripheral blood of patients
11839665 distinct methylation pattern in bladder cancer with frequent methylation of RARbeta, DAPK, E-cadherin, and p16.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDCaMK II alpha subunitdeath-associated protein kinase 2--Pubmed
HPRDcalcium/calmodulin-dependent protein kinase IIA isoform 1Death associated protein kinase 2--Pubmed

Recent Publications on DAPK2:

Pubmed Logo
Targeted restoration of down-regulated DAPK2 tumor suppressor activity induces apoptosis in Hodgkin lymphoma cells.
Death-associated protein kinase 2 (DAPK2) is a...
9th October, 2009
Department of Experimental Medicine and Immunotherapy, Chair of Applied J Immunother. 2009 Jun;32(5):431-41.
DOI Direct Link
Immunokinases, a novel class of immunotherapeutics for targeted cancer therapy.
Certain characteristics of tumor cells make it possible to develop...
20th August, 2009
Department of Experimental Medicine and Immunotherapy, Chair of Applied Curr Pharm Des. 2009;15(23):2693-9.
DAPK2 is a novel E2F1/KLF6 target gene involved in their proapoptotic function.
Death-associated protein kinase 2 (DAPK2) belongs to a family of...
8th October, 2008
1Experimental Oncology/Hematology, Department of Clinical Research, Oncogene. 2008 Sep 25;27(43):5706-16. Epub 2008 Jun 2.
DOI Direct Link
Attenuation of EPO-dependent erythroblast formation by death-associated protein kinase-2.
The adult erythron is maintained via dynamic modulation of erythroblast...
6th September, 2008
Stem and Progenitor Cell Biology Program, Molecular Medicine Division, Blood. 2008 Aug 1;112(3):886-90. Epub 2008 Jun 5.
DOI Direct Link
Erythropoietin-dependent erythropoiesis: New insights and questions.
Committed erythroid progenitor cells require exposure to erythropoietin...
21st September, 2007
Maine Medical Center Research Institute and Program in Stem Cell Biology Blood Cells Mol Dis. 2006 Mar-Apr;36(2):232-8. Epub 2006 Mar 9.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7589101 Compounds and compositions as protein kinase inhibitors
7485418 Aberrantly methylated genes in pancreatic cancer
7423038 Compounds and compositions as protein kinase inhibitors
7251568 Methods and compositions for regulating bone and cartilage formation
6706867 DNA array sequence selection

View more patents.

DAPK2 results (if any) from reagent suppliers

Google CSE Logo
DAPK2 Antibody Death-Associated Protein kinase 2
DAPK2 antibody can be used for detection of DAPK2 by Western blot at 0.5 to 1 ug /ml. An approximately 42 kDa band can be detected. DAPK2 has no cross ...
http://www.prosci-inc.com/shop/catalog1/DAPK2-Antibody-p-610...

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p-DAPK2 (Ser 318)-R Antibody sc-21809-R
rabbit polyclonal IgG, 200 µg/ml; recommended for detection of Ser 318 phosphorylated DAPK2 (also desgnated DRP-1) of m, r and h origin by WB, IF and
ELISA ...
http://www.scbt.com/datasheet-21809-p-dapk2-ser-318-r-antibo...

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DAPK2 Antibody (N-term)
DAPK2 Antibody (N-term) Cell Function, DAPK2 Antibody (N-term) Apoptosis, DAPK2 Antibody (N-term) Protein Modification, DAPK2 Antibody (N-term) Cell ...
http://www.abgent.com/products/catalog_no/AP7033a...

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DAPK2 (C-18) Antibody sc-10084
goat polyclonal IgG, 200 µg/ml; epitope mapping at the C-terminus of DAPK2 of human origin; recommended for detection of DAPK2 of m, r and h origin by WB, ...
http://www.scbt.com/datasheet-10084-dapk2-c-18-antibody.html...

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Antibodies to Other Apoptosis-related Proteins
D3069, Anti-DAPK2 (11-25) antibody produced in rabbit, (polyclonal) .... WH0023604M1, Monoclonal Anti-DAPK2 antibody produced in mouse, 3D4 (monoclonal)
...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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DAPK Antibody / DAPK Antibodies
DAPK2 (C-18) Antibody, sc-10084, goat IgG, C-terminus (h), WB, IF, ELISA, m, r, h ... p-DAPK2 (Ser 318)-R Antibody, sc-21809-R, rabbit IgG, Ser 318 (h) ...
http://www.scbt.com/table-dapk.html...

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Antibody Products - IgG Polyclonal Antibodies - GenWay
DAPK2; - Death-associated protein kinase 2; N/A, IgG Polyclonal E, WB, Source: Goat ... DAPK2 RABBIT ANTIBODY;, IgG Polyclonal WB, Source: Rabbit ...
http://www.genwaybio.com/all_polyclonal_antibodies.php?fl=D...

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