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KCNE4
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 16563243 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17016049 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17016049 |
The non-synonymous single nucleotide polymorphism E145D may be associated with the atrial fibrillation phenotype. |
| 12670483 |
expressed strongly in heart, skeletal muscle, and kidney, less in placenta, lung, and liver, and weakly in brain and blood cells. Electrophysiological study showed that KCNE4 modulates the activation of the KCNQ1 channel. |
| 15707997 |
Based upon previous studies and the present results, it is concluded that both hKCNE4 and mKCNE4 have a drastic inhibitory impact on both hKCNQ1 and mKCNQ1 currents. |
| 12944270 |
KCNE4 beta-subunit has a drastic inhibitory effect on currents generated by Kv1.1 and Kv1.3 potassium channels |
Interacting gene products |
| Interaction Type |
Gene 1 |
Gene 2 |
Interaction description |
Complex |
Publication Link |
| HPRD | Potassium voltage gated channel, shaker related subfamily, member 1 | potassium voltage-gated channel, Isk-related family, member 4 | - | - | Pubmed |
| HPRD | potassium voltage-gated channel, shaker-related subfamily, member 1 | Potassium channel voltage gated ISK related subfamily member 4 | - | - | Pubmed |
| HPRD | potassium voltage-gated channel, KQT-like subfamily precursor, member 1 | potassium voltage-gated channel, Isk-related family, member 4 | - | - | Pubmed |
| HPRD | potassium voltage-gated channel, KQT-like subfamily precursor, member 1 | potassium voltage-gated channel, Isk-related family, member 4 | - | - | Pubmed |
| HPRD | protein kinase C, alpha | potassium voltage-gated channel, Isk-related family, member 4 | - | - | Pubmed |
Recent Publications on KCNE4: |  |
KCNE4 suppresses Kv1.3 currents by modulating trafficking, surface expression and channel gating.
Voltage-dependent potassium channels (Kv) play a crucial role in the... | 24th September, 2009
| Departament de Bioquimica i Biologia Molecular, Molecular Physiology
| J Cell Sci. 2009 Oct 15;122(Pt 20):3738-48. Epub 2009 Sep 22.
DOI Direct Link |
Loss of functional K+ channels encoded by ether-a-go-go-related genes in mouse myometrium prior to labour onset.
There is a growing appreciation that ion channels encoded by the... | 4th September, 2009
| Division of Basic Medical Sciences, Ion Channels And Cell Signaling
| J Physiol. 2009 May 15;587(Pt 10):2313-26. Epub 2009 Mar 30.
DOI Direct Link |
Distinct subdomains of the KCNQ1 S6 segment determine channel modulation by different KCNE subunits.
Modulation of voltage-gated potassium (KV) channels by the KCNE family of... | 19th August, 2009
| Division of Genetic Medicine, Department of Medicine, Center for
| J Gen Physiol. 2009 Sep;134(3):207-17. Epub 2009 Aug 17.
DOI Direct Link |
Gene expression in lungs of mice lacking the 5-hydroxytryptamine transporter gene.
BACKGROUND: While modulation of the serotonin transporter (5HTT) has shown... | 31st July, 2009
| Division of Pulmonary Sciences and Critical Care Medicine, University of
| BMC Pulm Med. 2009 May 10;9:19.
DOI Direct Link |
Expression and function of K(v)7 channels in murine myometrium throughout oestrous cycle.
This study represents an extensive characterisation of the expression and... | 25th July, 2009
| King's College London, St Thomas' Hospital Campus, UK.
| Pflugers Arch. 2009 Mar;457(5):1111-20. Epub 2008 Aug 16.
DOI Direct Link |
→View more research publications. |
KCNE4 results (if any) from reagent suppliers | 
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KCNE4 (FL-170) Antibody sc-66940
rabbit polyclonal IgG, 200µg/ml; epitope corresponding to amino acids 1-170 representing full length KCNE4 of human origin; recommended for detection of ...
http://www.scbt.com/datasheet-66940-kcne4-fl-170-antibody.ht...
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KCNE4 antibodies: Neuroscience > Neurotransmission > Receptors ...
KCNE4 antibodies. ... KCNE4 antibodies. Code. Name. Applications (see key) & Reactivity (see key). Image Abreview Publication. ab57013 · KCNE4 antibody ...
http://www.abcam.com/index.html?t=231016&pt=1&c=392&ei=&mu=r...
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KCN Antibody / KCN Antibodies
KCNE4 (E-13) Antibody, sc-34911, goat IgG, C-terminus (h), WB, IF, ELISA, h > m, r. KCNE4 (M-12) Antibody, sc-34913, goat IgG, internal (h), WB, IF, ELISA ...
http://www.scbt.com/table-kcn.html...
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Anti-Potassium Channel KCNE3 (MiRP2) (K0140) - Data Sheet
(IsK, MiNK), KCNE2 (MiRP1), KCNE4 (MiRP3) and. KCNE5 (MiRP4). KCNE1 is the founding member of the family and was initially believed to form a K+ channel
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http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Datashee...
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KCNE4 siRNA (h) sc-45535
Click here for details. contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: KCNE4 (h)-PR: sc-45535-PR, 20 µl ...
http://www.scbt.com/datasheet-45535-kcne4-sirna-h.html...
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Abcam antibodies and reagents product map
... KCNC3 antibodies (6) · KCNC4 antibodies (2) · KCNE1 antibodies (4) · KCNE2 antibodies (3) · KCNE3 antibodies (1) · KCNE4 antibodies (1) ...
http://www.abcam.com/index.html?cl=248&pageconfig=productmap...
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