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ALK
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18165268 |
besides MYCN and ALK, other genes proximal and distal to MYCN are highly expressed in neuroblastoma |
| 16604305 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17922009 |
Oncogenic NPM1-ALK contains the ALK catalytic domain plus NPM1 oligomerization motif and mediates malignant cell transformation by epigenetic silencing of signal transducer and activator of transcription STAT5A in T-cell anaplastic large cell lymphomas. |
| 18166835 |
ALK is part of a fusion protein linked to histological characteristics in a subset of lung neoplasms. |
| 18097461 |
Translocations or deregulated expression of ALK contribute to oncogenesis and genetic or pharmacological tools, aimed at neutralizing its activity in anaplastic lymphoma [REVIEW] |
| 17904822 |
Pleiotrophin failed to activate anaplastic lymphoma kinase (ALK) in neuroblastoma/glioblastoma cells expressing this receptor. ALK is still an orphan receptor in vertebrates. |
| 17690253 |
JunB is a critical target of mTOR and is translationally regulated in NPM-ALK-positive lymphomas. |
| 17537995 |
identify splicing factor as a novel nucleophosmin 1/anaplastic lymphoma kinase-binding protein and substrate |
| 17681947 |
phosphorylation of ALK in PTN-stimulated cells is mediated through the PTN/RPTPbeta/zeta signaling pathway |
| 15226403 |
ALK receptor tyrosine kinase has roles promoting cell growth and neurite outgrowth | →View more information from publications. |
Recent Publications on ALK: |  |
MPN- and Real-Time-Based PCR Methods for the Quantification of Alkane Monooxygenase Homologous Genes (alkB) in Environmental Samples.
Hydrocarbons are major contaminants of soil ecosystems as a result of... | 3rd November, 2009
| Department for Terrestrial Ecogenetics, Helmholtz Zentrum Munchen,
| Methods Mol Biol. 2010;599:59-68.
DOI Direct Link |
Component-resolved diagnosis of pollen allergy based on skin testing with profilin, polcalcin and lipid transfer protein pan-allergens.
BACKGROUND: Allergy diagnosis needs to be improved in patients suffering... | 31st October, 2009
| Departamento de I+D, ALK-Abello, Madrid, Spain.
| Clin Exp Allergy. 2009 Nov;39(11):1764-73.
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Analysis of human T-cell lymphotropic virus in CD25+ anaplastic large cell lymphoma in children.
Anaplastic large cell lymphoma (ALCL) is recognized as 2 distinct... | 30th October, 2009
| Consultoria em Patologia, Rua Major Leonidas Cardoso 739, Botucatu, SP,
| Am J Clin Pathol. 2009 Jul;132(1):28-33.
DOI Direct Link |
Infant Anaplastic Large Cell Lymphoma with Hemophagocytic Syndrome.
Abstract Anaplastic large cell lymphoma (ALCL), ALK-positive, is uncommon... | 30th October, 2009
| 1 PathWest, Princess Margaret Hospital.
| Pediatr Dev Pathol. 2009 Oct 19.
DOI Direct Link |
Selective allergy to lobster in a case of primary sensitization to house dust mites.
Allergy to only 1 kind of seafood is uncommon. We report a case of... | 30th October, 2009
| Department of Allergology, Hospital General Yague, Burgos, Spain.
| J Investig Allergol Clin Immunol. 2009;19(5):409-13.
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→View more research publications. |
Press Releases on ALK:
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| Japanese Cancer Association and Debiopharm Honour Japanese Research |
29th October, 2008 |
Debiopharm Group |
LAUSANNE, Switzerland, October 29 /PRNewswire/ -- Debiopharm Group
(Debiopharm), a global biopharmaceutical development specialist that focuses
on serious medical conditions and particularly
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| Persistent Vaccination Effect of GRAZAX(R) After Completion of Treatment |
22nd October, 2008 |
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COPENHAGEN, October 22 /PRNewswire/ -- Breakthrough: Results from the fourth year in a long-term clinical study
prove the disease modifying effect of GRAZAX(R). For the first time ever, it
is
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| Positive SPA Reply From the FDA for TopoTarget's Pivotal Trial With Belinostat in PTCL |
5th September, 2008 |
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COPENHAGEN, Denmark, September 5 /PRNewswire/ -- TopoTarget A/S (OMX: TOPO) announced that a positive reply from the FDA
was received on a Special Protocol Assessment (SPA) for a phase III trial
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| Scripps Translational Science Institute Contributes to Discovery of Predisposition Gene for Childhood Cancer |
25th August, 2008 |
Scripps Translational Science Institute |
SAN DIEGO, Aug. 25 /PRNewswire/ -- Researchers at Scripps Translational
Science Institute (STSI) have contributed to a major genetic breakthrough --
the discovery of a gene responsible for the
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| Gene That Causes Childhood Cancer Neuroblastoma Is Found |
25th August, 2008 |
The Children's Hospital of Philadelphia |
--May Lead to New Prevention and Treatment Strategies--
PHILADELPHIA, Aug. 25 /PRNewswire-USNewswire/ -- Scientists have discovered gene mutations that are the main
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ALK results (if any) from reagent suppliers | 
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