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ALOX12


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Symbol:ALOX12
Name(s):arachidonate 12-lipoxygenase
Type:protein-coding
Organism:Homo sapiens
Synonyms:12-LOX, 12S-LOX, LOG12
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
12664313 Observational study of gene-disease association. (HuGE Navigator)
15308583 Observational study of gene-disease association. (HuGE Navigator)
16514435 Observational study of gene-disease association. (HuGE Navigator)
16598376 Observational study of gene-disease association. (HuGE Navigator)
17151091 Observational study of gene-disease association. (HuGE Navigator)
17236225 Observational study of gene-disease association. (HuGE Navigator)
17460548 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17520163 Observational study of gene-disease association. (HuGE Navigator)
17893696 Observational study of gene-disease association. (HuGE Navigator)
17520163 there is no association between polymorphism in ALOX15 and bone mineral density phenotypes, but genetic variation in ALOX12 seems to play a role in determining bone structure in Caucasian women

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDarachidonate 12-lipoxygenase-12-LOX interacts with Lamin A.-Pubmed
HPRDarachidonate 12-lipoxygenaseunnamed protein product--Pubmed
HPRDarachidonate 12-lipoxygenaseunnamed protein product--Pubmed
HPRDarachidonate 12-lipoxygenaseintegrin, beta 4--Pubmed
HPRDarachidonate 12-lipoxygenaseintegrin, beta 4--Pubmed
BINDarachidonate 12-lipoxygenaseintegrin beta 4 isoform 1 precursor12-LOX interacts with Integrin-beta4.-Pubmed
BINDarachidonate 12-lipoxygenasekeratin 512-LOX interacts with K5.-Pubmed
BINDarachidonate 12-lipoxygenaseG-protein-coupled receptor induced protein12-LOX interacts with C8FW.-Pubmed

Recent Publications on ALOX12:

Pubmed Logo
Lack of association of ALOX12 and ALOX15 polymorphisms with aspirin-exacerbated respiratory disease in Korean patients.
BACKGROUND: Inflammatory myofibroblastic tumors (IMFTs) of the larynx are...
12th September, 2009
Ann Allergy Asthma Immunol. 2009 Jul;103(1):84-6.
Mechanistic investigations of human reticulocyte 15- and platelet 12-lipoxygenases with arachidonic acid.
Human reticulocyte 15-lipoxygenase-1 (15-hLO-1) and human platelet...
14th August, 2009
Chemistry and Biochemistry Department, University of California, Santa Biochemistry. 2009 Jul 7;48(26):6259-67.
DOI Direct Link
Variation in eicosanoid genes, non-fatal myocardial infarction and ischemic stroke.
OBJECTIVES: Eicosanoids are lipid mediators that may play a role in...
11th August, 2009
Cardiovascular Health Research Unit, Department of Medicine, University of Atherosclerosis. 2009 Jun;204(2):e58-63. Epub 2008 Nov 1.
DOI Direct Link
p63 directly induces expression of Alox12, a regulator of epidermal barrier formation.
Please cite this paper as: p63 directly induces expression of Alox12, a...
27th June, 2009
Department of Molecular and Cellular Biology, Baylor College of Medicine, Exp Dermatol. 2009 Jun 23.
DOI Direct Link
Molecular analysis of 250 patients with autosomal recessive congenital ichthyosis: evidence for mutation hotspots in ALOXE3 and allelic heterogeneity in ALOX12B.
In recent years several new genes for autosomal recessive congenital...
23rd June, 2009
Division of Dermatogenetics, Cologne Center for Genomics, University of J Invest Dermatol. 2009 Jun;129(6):1421-8. Epub 2009 Jan 8.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7598031 Method for the detection of gene transcripts in blood and uses thereof
6479546 Allosteric inhibitors of lipoxygenase
6706867 DNA array sequence selection
6867348 Methods and compositions for screening for angiogenesis modulating compounds
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector

View more patents.

ALOX12 results (if any) from reagent suppliers

Google CSE Logo
12-LO (H-100) Antibody sc-32939
种属, 基因名称, 基因ID, 染色质位置, 亚型(mRNA)即位号码, 蛋白质即位号码, OMIM™ 号码. 人类, ALOX12, 239, 17p13.1, NM_000697 · P18054 ...
http://www.scbt.com/zh/datasheet-32939-12-lo-h-100-antibody....

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330396 3,3′,5,5′-Tetrabromobisphenol A 97%
mp, 178-181 °C(lit.) Gene Information, human ... ALOX12(239), ALOX15(246). Safety. Hazard Codes, Xi. Risk Statements, 36/37/38. Safety Statements, 26-36
...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=3303...

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12-LO (H-100) Antibody sc-32939
Humano, ALOX12, 239, 17p13.1, NM_000697 · P18054 · 152391. Ratón, Alox12, 11684, 11 B3, P39655, No Aplicable. Información sobre pedidos ...
http://www.scbt.com/es/datasheet-32939-12-lo-h-100-antibody....

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D2773 Dithranol ≥90% (HPLC)
assay, ≥90% (HPLC). mp, 178-181 °C(lit.) Gene Information, mouse ... Alox12( 11684). Safety. Personal Protective Equipment, dust mask type N95 (US), ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=D277...

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12-LO (H-100) Antibody sc-32939
Species, 遺伝子名, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. ヒト, ALOX12, 239, 17p13.1, NM_000697 ...
http://www.scbt.com/ja/datasheet-32939-12-lo-h-100-antibody....

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36942 2-Bromophenol OEKANAL®, analytical standard
bp, 195 °C(lit.) mp, 3-7 °C(lit.) density, 1.492 g/mL at 25 °C(lit.) Gene Information, human ... ALOX12(239), ALOX15(246) ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...

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N5023 Nordihydroguaiaretic acid NDGA ≥90% (HPLC), from Larrea ...
assay, ≥90% (HPLC). mp, 184-186 °C(lit.) Gene Information, human ... ALOX15(246 ), PTGS1(5742), PTGS2(5743). mouse ... Alox12(11684) ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...

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