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ALOX5AP


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Gene DB Home
Symbol:ALOX5AP
Name(s):arachidonate 5-lipoxygenase-activating protein
Type:protein-coding
Organism:Homo sapiens
Synonyms:FLAP
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18318662 Observational study of gene-disease association. (HuGE Navigator)
18323512 Observational study of gene-disease association. (HuGE Navigator)
12911785 Observational study of gene-disease association. (HuGE Navigator)
14702425 Observational study of gene-disease association. (HuGE Navigator)
14749922 Observational study of gene-disease association. (HuGE Navigator)
15640973 Observational study of gene-disease association. (HuGE Navigator)
15731479 Observational study of gene-disease association. (HuGE Navigator)
15784112 Observational study of gene-disease association. (HuGE Navigator)
15876305 Observational study of gene-disease association. (HuGE Navigator)
15886380 Observational study and clinical trial of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDarachidonate 5-lipoxygenasearachidonate 5-lipoxygenase-activating protein--Pubmed
HPRDarachidonate 5-lipoxygenasearachidonate 5-lipoxygenase-activating protein--Pubmed

Recent Publications on ALOX5AP:

Pubmed Logo
Sex-specific association of depression and a haplotype in leukotriene A4 hydrolase gene.
OBJECTIVE: To assess whether genetic variants involved in inflammation...
30th October, 2009
Department of Biostatistics and Epidemiology, College of Public Health, Psychosom Med. 2009 Sep;71(7):691-6. Epub 2009 Jul 21.
DOI Direct Link
Inhibitors of the 5-lipoxygenase pathway in atherosclerosis.
The inflammatory environment within the atherosclerotic lesion stimulates...
17th September, 2009
Department of Cardiology and Center for Molecular Medicine, Karolinska Curr Pharm Des. 2009;15(27):3116-32.
Leukotriene pathway polymorphisms are associated with altered cysteinyl leukotriene production in children with acute asthma.
Cysteinyl leukotrienes (cysLTs) are pro-inflammatory mediators with...
4th September, 2009
School of Paediatrics and Child Health, University of Western Australia, Prostaglandins Leukot Essent Fatty Acids. 2009 Jul;81(1):9-15. Epub 2009
DOI Direct Link
Variation in eicosanoid genes, non-fatal myocardial infarction and ischemic stroke.
OBJECTIVES: Eicosanoids are lipid mediators that may play a role in...
11th August, 2009
Cardiovascular Health Research Unit, Department of Medicine, University of Atherosclerosis. 2009 Jun;204(2):e58-63. Epub 2008 Nov 1.
DOI Direct Link
Association of genetic variants with chronic kidney disease in Japanese individuals with type 2 diabetes mellitus.
Although diabetes mellitus has been recognized as a risk factor for...
8th August, 2009
Department of Cardiovascular Medicine, Inabe General Hospital, Inabe, Int J Mol Med. 2009 Apr;23(4):529-37.

View more research publications.

Patents:

Patents logo
US Patent No.Title
7611902 Diagnostic method for myopathy
6673908 Tumor necrosis factor receptor 2
6905827 Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
7026121 Methods and compositions for diagnosing and monitoring transplant rejection
7235358 Methods and compositions for diagnosing and monitoring transplant rejection

View more patents.

ALOX5AP results (if any) from reagent suppliers

Google CSE Logo
ALOX5AP Antibody (C-term)
(RIGHT)Western blot analysis of anti-ALOX5AP Antibody (C-term) (Cat.#AP7897b) in mouse intestine tissue lysates (35ug/lane). ALOX5AP(arrow) was detected ...
http://www.abgent.com/products/catalog_no/AP7897b_ALOX5AP_An...

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Peptide-affinity Purified Polyclonal Antibody to FLAP/ALOX5AP (C Term)
protein Official Gene Symbol - ALOX5AP GenBank Accession Number NP_001620 LocusLink ID ... Immunofluoroscence staining of ALOX5AP using IMG-3160 in
primary ...
http://www.imgenex.com/tds/IMG-3160.pdf...

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Polyclonal Antibodies :: Page 13
ALOX5AP Antibody, 45-242, H, D, E, WB, (IN) FLAP / ALOX5AP. Alpha Internexin Antibody, 50-251, H, M, R, WB, IF, Alpha Internexin (NF 66) ...
http://www.prosci-inc.com/shop/catalog1/Polyclonal-Antibodie...

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Abgent - Cell and Function Antibodies
AP7856bNEW, ALOX5 Antibody (C-term), WB, E, H. AP7897bNEW, ALOX5AP Antibody (C- term), WB, IHC, E, H, M. AP7897cNEW, ALOX5AP Antibody (Center), WB, IHC, E, H
...
http://www.abgent.com/products/category/cell_function...

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FLAP (FL-161) Antibody sc-28815
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIMâ„¢ Number. Human, ALOX5AP, 241, 13q12.3, NM_001629 ...
http://www.scbt.com/datasheet-28815-flap-fl-161-antibody.htm...

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Phospho-5-Lipoxygenase (Ser663) Antibody #3749
Leukotriene synthesis also requires 5-lipoxygenase-activating protein (FLAP, ALOX5AP), a nuclear membrane-bound protein that binds arachidonic acid and is
...
http://www.cellsignal.com/products/3749.html...

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FLAP (FL-161) Antibody sc-28815
Species, Nome del gene, Codice del gene, Locus cromosoma, Isoform (mRNA) Accession #, codice accesso proteina, Numero d' ordine. Human, ALOX5AP, 241,
13q12. ...
http://www.scbt.com/it/datasheet-28815-flap-fl-161-antibody....

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