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ALOX12B
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17436029 |
Formation of a ligand for the nuclear receptor PPARalpha may be one possibility by which 12R-LOX and eLOX3 contribute to epidermal differentiation. |
| 17139268 |
Our data contribute to an enlargement of the spectrum of mutations for the development of efficient molecular genetic tests for analysis of at risk individuals whose carrier status is unknown. |
| 12664578 |
Isoenzyme is characterized. |
| 15629692 |
12R-LOX hydrolase functions in the normal process of skin differentiation, and that the loss of function mutations are the basis of the LOX-dependent form of Non-bullous congenital ichthyosiform erythroderma. |
| 11773004 |
Lipoxygenase-3 (ALOXE3) and 12(R)-lipoxygenase (ALOX12B) are mutated in non-bullous congenital ichthyosiform erythroderma (NCIE) linked to chromosome 17p13.1. |
Recent Publications on ALOX12B: |  |
Moisturizers change the mRNA expression of enzymes synthesizing skin barrier lipids.
In a previous study, 7-week treatment of normal human skin with two test... | 23rd October, 2009
| Department of Medical Sciences, Dermatology and Venereology, University
| Arch Dermatol Res. 2009 Sep;301(8):587-94. Epub 2009 May 23.
DOI Direct Link |
Candidate gene approach evaluates association between innate immunity genes and breast cancer risk in Korean women.
OBJECTIVES: This study was conducted to investigate the role of common... | 16th September, 2009
| Department of Preventive Medicine, Seoul National University College of
| Carcinogenesis. 2009 Sep;30(9):1528-31. Epub 2009 Apr 16.
DOI Direct Link |
Nonsense mutation in the ALOX12B gene leads to autosomal recessive congenital ichthyosis in a Lebanese family.
The n-6 polyunsaturated fatty acid 5-lipoxygenase pathway has been shown... | 22nd August, 2009
| Department of Dermatology, Columbia University, New York, NY, USA.
| J Eur Acad Dermatol Venereol. 2009 Aug 20.
DOI Direct Link |
Molecular analysis of 250 patients with autosomal recessive congenital ichthyosis: evidence for mutation hotspots in ALOXE3 and allelic heterogeneity in ALOX12B.
In recent years several new genes for autosomal recessive congenital... | 23rd June, 2009
| Division of Dermatogenetics, Cologne Center for Genomics, University of
| J Invest Dermatol. 2009 Jun;129(6):1421-8. Epub 2009 Jan 8.
DOI Direct Link |
Development of an ichthyosiform phenotype in Alox12b-deficient mouse skin transplants.
12R-lipoxygenase (12R-LOX) represents a key enzyme of a recently... | 23rd June, 2009
| Genome Modifications and Carcinogenesis, German Cancer Research Center,
| J Invest Dermatol. 2009 Jun;129(6):1429-36. Epub 2009 Jan 1.
DOI Direct Link |
→View more research publications. |
ALOX12B results (if any) from reagent suppliers | 
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Epidermis-type 12-LO (C-20) Antibody sc-27362
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, ALOX12B, 242, 17p13.1, NM_001139 ...
http://www.scbt.com/datasheet-27362-epidermis-type-12-lo-c-2...
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Epidermis-type 12-LO (C-20) Antibody sc-27362
Humano, ALOX12B, 242, 17p13.1, NM_001139 · O75342 · 603741. Ratón, Alox12b, 11686, 11 B3, O70582, No Aplicable. Información sobre pedidos ...
http://www.scbt.com/es/datasheet-27362-epidermis-type-12-lo-...
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Epidermis-type 12-LO (C-20) Antibody sc-27362
Humano, ALOX12B, 242, 17p13.1, NM_001139 · O75342 · 603741. camundongo, Alox12b, 11686, 11 B3, O70582, N/A. Informacoes sobre ordens ...
http://www.scbt.com/pt/datasheet-27362-epidermis-type-12-lo-...
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Epidermis-type 12-LO (C-20) Antibody sc-27362
Species, 遺伝子名, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. ヒト, ALOX12B, 242, 17p13.1, NM_001139 ...
http://www.scbt.com/ja/datasheet-27362-epidermis-type-12-lo-...
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