Recent Publications on : |  |
Inhibition of tumor growth progression by antiandrogens and mTOR inhibitor in a Pten-deficient mouse model of prostate cancer.
Androgen receptors have been shown to play a critical role in prostate...
Direct Link | 8th October, 2009
| Department of Imaging, Merck Research Laboratories, Boston, Massachusetts
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Tuberous sclerosis complex suppression in cerebellar development and medulloblastoma: separate regulation of mammalian target of rapamycin activity and p27 Kip1 localization.
During development, proliferation of cerebellar granule neuron precursors...
Direct Link | 8th October, 2009
| Department of Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer
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Inhibition of mTOR signaling in Parkinson's disease prevents L-DOPA-induced dyskinesia.
Parkinson's disease (PD), a disorder caused by degeneration of the...
Direct Link | 30th September, 2009
| Department of Neuroscience, Karolinska Institutet, Retzius vag 8, 171 77
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Thwarting dyskinesia by targeting mTORC1.
In a mouse model of Parkinson's disease, new evidence shows that l-DOPA,...
Direct Link | 30th September, 2009
| Center for Neural Science, New York University, New York, NY 10003, USA.
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Get stoned in GABAergic synapses.
During development, proliferation of cerebellar granule neuron precursors...
Direct Link | 24th September, 2009
| Ken Mackie is in the Gill Center and the Department of Psychological &
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Lipid-induced mTOR activation in rat skeletal muscle reversed by exercise and 5'-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside.
The serine/threonine protein kinase, mammalian target of rapamycin (mTOR)...
Direct Link | 24th September, 2009
| Exercise Metabolism Group, School of Medical Sciences, RMIT University,
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CD137 ligand-mediated reverse signals increase cell viability and cytokine expression in murine myeloid cells: involvement of mTOR/p70S6 kinase and Akt.
Cross-linking of CD137 ligand (CD137L), a member of the TNF family, with...
Direct Link | 23rd September, 2009
| Graduate School of Life Science and Biotechnology, Pochon CHA University,
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Ageing: A midlife longevity drug?
In a mouse model of Parkinson''s disease, new evidence shows that l-DOPA,...
Direct Link | 19th September, 2009
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Rapamycin fed late in life extends lifespan in genetically heterogeneous mice.
Inhibition of the TOR signalling pathway by genetic or pharmacological...
Direct Link | 19th September, 2009
| The Jackson Laboratory, Bar Harbor, Maine 04609, USA.
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Rapamycin delays tumor development in murine livers by inhibiting proliferation of hepatocytes with DNA damage.
In this study, everolimus (RAD001) was used to determine the role of...
Direct Link | 22nd August, 2009
| Clinic of Hepatology, Gastroenterology, and Endocrinology, Hannover
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mTOR regulates memory CD8 T-cell differentiation.
Memory CD8 T cells are a critical component of protective immunity, and...
Direct Link | 21st August, 2009
| Emory Vaccine Center and Department of Microbiology and Immunology,
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Genetic variation in healthy oldest-old.
Individuals who live to 85 and beyond without developing major age-related...
Direct Link | 15th August, 2009
| Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer
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The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment.
Effector T cell differentiation requires the simultaneous integration of...
Direct Link | 18th July, 2009
| Sidney-Kimmel Comprehensive Cancer Center, Johns Hopkins University School
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m(en)TOR(ing) differentiating T helper cells.
The decision of naive Th cells to assume the fate of effector or regulator...
Direct Link | 18th July, 2009
| Department of Medicine, Division of Rheumatology, Immunology, and Allergy,
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GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer.
Genome-wide copy number analyses of human cancers identified a frequent...
Direct Link | 3rd July, 2009
| Department of Medical Oncology, Dana-Farber Cancer Institute, Boston,
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