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ALPL
| Symbol: | ALPL | | Name(s): | alkaline phosphatase, liver/bone/kidney | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | AP-TNAP, FLJ40094, HOPS, MGC161443, TNAP, TNSALP | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18158785 |
A monoclonal antibody against tissue-nonspecific alkaline phosphatase (ALP) is established that will be a useful tool for effective measurement of liver-ALP, a marker of liver disease, by immunocapture enzymatic assay. |
| 17922851 |
The results provide an explanation of the lethal phenotype in the patient where the two ALPL alleles are non-functional and in the asymptomatic father where over-expression of the normal allele could counteract the effect of the c.1133A>T mutation. |
| 15230135 |
Observational study of gene-disease association. (HuGE Navigator) |
| 15660230 |
Observational study of gene-disease association. (HuGE Navigator) |
| 15824850 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17043047 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17195227 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17563703 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18037100 |
Inverse relationships between neuropeptide Y (NPY) and biomarkers (bone and serum alkaline phosphatase) levels of bone turnover suggest that NPY may be implicated in low bone turnover in dialysis patients by a parathyroid-independent mechanism. |
| 17719863 |
While the wild-type protein reached the cell membrane within the first 24h after transfection, the mutants reached the membrane with delays of 24, 48 or 72 h. | →View more information from publications. |
Recent Publications on ALPL: |  |
AN IN VITRO ASSESSMENT OF A CELL-CONTAINING COLLAGENOUS EXTRACELLULAR MATRIX-LIKE SCAFFOLD FOR BONE TISSUE ENGINEERING.
Extracellular matrix (ECM) consists of a complex mixture of macromolecules... | 26th September, 2009
| McGill University, Faculty of Dentistry, Montreal, Quebec, Canada;
| Tissue Eng Part A. 2009 Sep 24.
DOI Direct Link |
Chondrogenic differentiation potential of osteoarthritic chondrocytes and their possible use in matrix-associated autologous chondrocyte transplantation.
ABSTRACT: INTRODUCTION: Autologous chondrocyte transplantation (ACT) is a... | 3rd September, 2009
| Tissue Engineering Laboratory and Berlin-Brandenburg Center for
| Arthritis Res Ther. 2009 Sep 2;11(5):R133.
DOI Direct Link |
Integrative genomic analyses of ZEB2: Transcriptional regulation of ZEB2 based on SMADs, ETS1, HIF1alpha, POU/OCT, and NF-kappaB.
Epithelial-to-mesenchymal transition (EMT) is defined as phenotypic change... | 19th August, 2009
| M&M Medical BioInformatics, Hongo 113-0033, Japan.
| Int J Oncol. 2009 Jun;34(6):1737-42.
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Notch signaling enhances osteogenic differentiation while inhibiting adipogenesis in primary human bone marrow stromal cells.
OBJECTIVE: The Notch signaling pathway has been shown to play a role in... | 15th July, 2009
| Department of Pediatrics, University Clinic Dresden, Dresden, Germany.
| Exp Hematol. 2009 Jul;37(7):867-875.e1.
DOI Direct Link |
Temporal analysis of neural differentiation using quantitative proteomics.
The ability to derive neural progenitors, differentiated neurons and glial... | 11th July, 2009
| Institute of Bioinformatics, International Technology Park, Bangalore,
| J Proteome Res. 2009 Mar;8(3):1315-26.
DOI Direct Link |
→View more research publications. |
ALPL results (if any) from reagent suppliers | 
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ALPL secondary antibody, Alkaline Phosphatase Conjugated Affinity ...
Buy quality rabbit ALPL secondary antibody (interacts with goat igg f(ab')2), anti-ALPL, Alkaline Phosphatase Conjugated Affinity Purified Anti-GOAT IgG ...
http://www.genwaybio.com/product_info.php?products_id=294068...
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Immunohistochemistry : Alkaline Phosphatase/ALPL - R&D Systems
Alkaline phosphatase (ALPL) was detected in human BG01V embryonic stem cell line using 10 µg/mL mouse anti-human/mouse/rat ALPL monoclonal antibody (Catalog ...
http://www.rndsystems.com/ihc_molecule_images.aspx?m=1047...
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ALPL secondary antibody, Alkaline Phosphatase Conjugated Affinity ...
Buy quality goat ALPL secondary antibody (interacts with mouse igm (mu chain)), anti-ALPL, Alkaline Phosphatase Conjugated Affinity Purified Anti-MOUSE IgM ...
http://www.genwaybio.com/product_info.php?products_id=294276...
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Mouse Alkaline Phosphatase Affinity Purified Polyclonal Ab
Anti-mouse Alkaline Phosphatase/ALPL Antibody. FOR RESEARCH USE ONLY. ... Alkaline Phosphatase encoded by the ALPL gene (rmALPL; aa 18 - 503; ...
http://www.rndsystems.com/pdf/AF2910.pdf...
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ALPL secondary antibody, Alkaline Phosphatase Conjugated Affinity ...
Buy quality rabbit ALPL secondary antibody (interacts with sheep igg f(c)), anti -ALPL, Alkaline Phosphatase Conjugated Affinity Purified Anti-SHEEP IgG F(c) ...
http://www.genwaybio.com/product_info.php?products_id=294476...
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Recombinant Mouse Alkaline Phosphatase/ALPL
Alkaline Phosphatase/ALPL. Catalog Number: 2910AP. Background ... Alpl gene is a key regulator of bone mineralization in mice (2). A variety of mutations in ...
http://www.rndsystems.com/pdf/2910-AP.pdf...
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ALPL secondary antibody, Alkaline Phosphatase Conjugated Affinity ...
Buy quality goat ALPL secondary antibody (interacts with mouse igg), anti-ALPL, Alkaline Phosphatase Conjugated Affinity Purified Anti-MOUSE IgG (H&L) ...
http://www.genwaybio.com/product_info.php?products_id=294245...
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