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ALPP


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Gene DB Home
Symbol:ALPP
Name(s):alkaline phosphatase, placental (Regan isozyme)
Type:protein-coding
Organism:Homo sapiens
Synonyms:ALP, PLAP
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
14595869 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
12851398 the beta-N-acetylglucosaminyl phosphate diester residue is attached to the glycosylphosphatidylinositol anchor of human placental alkaline phosphatase and is a target of the channel-forming toxin aerolysin
12081485 Proximity of the protein moiety of a GPI-anchored protein to the membrane surface: a FRET study.
12372831 the structural differences in human AP isoforms are demonstrated through models
15946677 analysis of human placental alkaline phosphatase in complex with functional ligands
11857742 The PLAP D allele contains two amino acid substitutions: P209R (692C>G) and E429G (1352 A>G).
16893177 The role of the N-terminus and its microenvironment in determining the enzyme stability and catalysis using human placental (PLAP) and tissue-nonspecific AP (TNAP) as paradigms, is analyzed.
15715171 receptor for Aeromonas sobria hemolysin.
16815919 crystal structure of strontium-substituted human placental alkaline phosphatase shows that strontium substitutes the calcium ion with concomitant modification of the metal coordination

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDplacental alkaline phosphatase precursorglycosylphosphatidylinositol specific phospholipase D1 isoform 1 precursor--Pubmed
HPRDplacental alkaline phosphatase precursorglycosylphosphatidylinositol specific phospholipase D1 isoform 1 precursor--Pubmed
HPRDplacental alkaline phosphatase precursorphosphatidylinositol glycan anchor biosynthesis, class K precursor--Pubmed

Recent Publications on ALPP:

Pubmed Logo
Generation and characterization of EphA1 receptor tyrosine kinase reporter knockout mice.
Eph receptor tyrosine kinases (RTKs) are a highly conserved family of...
7th October, 2009
Leukaemia Foundation Research Unit, Queensland Institute of Medical Genesis. 2008 Oct;46(10):553-61.
DOI Direct Link
Mid-urethral synthetic slings in the treatment of urodynamic female stress urinary incontinence without concomitant pelvic prolapse repair: 4-year health-related quality of life outcomes.
OBJECTIVE To report 4-year health-related quality of life (HRQL) outcome...
15th September, 2009
Department of Urology, Concord Repatriation General Hospital, Sydney, NSW, BJU Int. 2009 Aug 28.
DOI Direct Link
The presence of transurethral cystometry catheter and type of stress test affect the measurement of abdominal leak point pressure (ALPP) in women with stress urinary incontinence (SUI).
AIMS: Abdominal leak point pressure (ALPP) measurements in female SUI may...
21st August, 2009
Marmara University School of Medicine, Department of Urology, Istanbul, Neurourol Urodyn. 2009 Aug 19.
DOI Direct Link
Assisted living pilot program: utilization and cost findings.
Objective. The Department of Veterans Affairs funded assisted living,...
22nd April, 2009
VA Puget Sound Health Care System and University of Washington, 1100 Olive J Aging Health. 2009 Feb;21(1):208-25.
DOI Direct Link
Assisted living pilot program: background, methods, and facility characteristics.
Objectives. The Department of Veterans Affairs (VA) funded assisted living...
22nd April, 2009
Edward Hines Jr. VA Hospital and Northwestern University. J Aging Health. 2009 Feb;21(1):172-89.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7588771 Microorganisms for therapy
6071726 Method, reagents and kit for diagnosis and targeted screening for p53 mutations
5915036 Method of estimation
5889599 Holography imaging apparatus holography display apparatus holography imaging method and holography display method
5642384 Trellis coded modulation scheme with low envelope variation for mobile radio by constraining a maximum modulus of a differential phase angle

View more patents.

ALPP results (if any) from reagent suppliers

Google CSE Logo
ALPP antibody, ALPP (alkaline phosphatase. placental (Regan ...
Buy quality rabbit ALPP antibody (interacts with human), anti-ALPP, ALPP ( alkaline phosphatase. placental (Regan isozyme)) antibody, rabbit polyclonal ...
http://www.genwaybio.com/product_info.php?products_id=43718...

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Polyclonal Antibodies :: Page 13
... E, WB, IHC, Alpha2-antiplasmin. ALPI Antibody, 49-380, H, E, WB, IHC, IF, IP , Alkaline Phosphatase. ALPP Antibody, 48-653, H, IHC, Alkaline Phosphatase ...
http://www.prosci-inc.com/shop/catalog1/Polyclonal-Antibodie...

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Antibodies
ALPP(250), human, ELISA (i), ICC, IHC (f), IHC (p), RIA, WB, pricing. B7684, Monoclonal Anti-Breast Cancer Resistance Protein antibody produced in mouse ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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Alkaline Phosphatase (L-19) Antibody sc-15065
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, ALPP, 250, 2q37.1, NM_001632 ...
http://www.scbt.com/datasheet-15065-Alkaline-Phosphatase-l-1...

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A2080 Monoclonal Anti-Alkaline Phosphatase, Human Placental ...
extent of labeling, 2 mg antibody per mL bed volume. application(s), immunoprecipitation: suitable. isotype, IgG2a. Gene Information, human ... ALPP(
250) ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...

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Alkaline Phosphatase (D-3) Antibody sc-137213
Human, ALPP, 250, 2q37.1, NM_000478, NM_001127501, NM_001631, NM_001632, NM_031313 · P05187 · 171800. Human, ALPPL2, 251, 2q37.1, NM_000478, NM_001127501
, ...
http://www.scbt.com/datasheet-137213-alkaline-phosphatase-d-...

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A2951 Monoclonal Anti-Alkaline Phosphatase, Human Placental ...
... of human cell lines expressing PLAP in nude mice2. isotype, IgG2a. Gene Information, human ... ALPP(250). shipped in, dry ice. storage temp. −20°C ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...

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