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DARC


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Symbol:DARC
Name(s):Duffy blood group, chemokine receptor
Type:protein-coding
Organism:Homo sapiens
Synonyms:CCBP1, CD234, Dfy, FY, GPD, GpFy, WBCQ1
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18248572 Observational study of gene-disease association. (HuGE Navigator)
11446431 Observational study of genotype prevalence and gene-disease association. (HuGE Navigator)
11813069 Observational study of gene-disease association. (HuGE Navigator)
12739041 Observational study of gene-disease association. (HuGE Navigator)
15327416 Observational study of gene-disease association. (HuGE Navigator)
15569072 Observational study of genotype prevalence. (HuGE Navigator)
15754970 Observational study of genotype prevalence. (HuGE Navigator)
15783300 Observational study of genotype prevalence. (HuGE Navigator)
15847654 Observational study of genetic testing. (HuGE Navigator)
18067501 Observational study of genetic testing. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDDuffy blood groupinterleukin 8 precursor--Pubmed
HPRDDuffy blood groupinterleukin 8 precursor--Pubmed
HPRDDuffy blood groupchemokine ligand 1--Pubmed
HPRDDuffy blood groupchemokine ligand 1--Pubmed
HPRDDuffy blood groupsmall inducible cytokine A2 precursor--Pubmed
HPRDDuffy blood groupsmall inducible cytokine A2 precursor--Pubmed
HPRDDuffy blood groupsmall inducible cytokine A5 precursor--Pubmed
HPRDDuffy blood groupsmall inducible cytokine A5 precursor--Pubmed

Recent Publications on DARC:

Pubmed Logo
The Duffy-null state is associated with a survival advantage in leukopenic HIV-infected persons of African ancestry.
Persons of African ancestry, on average, have lower white blood cell (WBC)...
29th October, 2009
Veterans Administration Research Center for AIDS and HIV-1 Infection, Blood. 2009 Sep 24;114(13):2783-92. Epub 2009 Jul 20.
DOI Direct Link
Inherited Cardiac Diseases Caused by Mutations in the Nav1.5 Sodium Channel.
Cardiac Diseases Caused by SCN5A Mutations. A prerequisite for a normal...
23rd October, 2009
The Danish National Research Foundation Centre for Cardiac Arrhythmia J Cardiovasc Electrophysiol. 2009 Oct 20.
DOI Direct Link
A Novel SCN5A Mutation in a Patient with Coexistence of Brugada Syndrome Traits and Ischaemic Heart Disease.
Brugada syndrome (BrS) is a primary electrical heart disease, which can...
16th October, 2009
The Danish National Research Foundation Centre for Cardiac Arrhythmia Case Report Med. 2009;2009:963645. Epub 2009 Oct 13.
DOI Direct Link
Influence of the Duffy antigen on pharmacokinetics and pharmacodynamics of recombinant monocyte chemoattractant protein (MCP-1, CCL-2) in vivo.
Monocyte chemoattractant protein-1 (MCP-1, CCL-2) binds to the Duffy...
14th October, 2009
Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Int J Immunopathol Pharmacol. 2009 Jul-Sep;22(3):615-25.
Development of atopic dermatitis in the DARC birth cohort.
Eller E, Kjaer HF, Host A, Andersen KE, Bindslev-Jensen C. Development of...
1st October, 2009
Department of Dermatology, Odense University Hospital, Odense C, Denmark. Pediatr Allergy Immunol. 2009 Sep 24.
DOI Direct Link

View more research publications.

BioNews Results for DARC

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BioPortfolio Logo
Quantitative Analysis of T-wave Morphology Increases Confidence in Drug-Induced Cardiac Repolarization Abnorma
Journal of Clinical Pharmacology:  Oct 21 2009 8:55PM Matching: darc
Symposium on breast cancer held in city
New Brunswick Tribune:  Oct 9 2009 4:15AM Matching: darc

Patents:

Patents logo
US Patent No.Title
7511467 Detection of lightning
7557405 High-density nonvolatile memory
7558391 Compander architecture and methods
7560339 Nonvolatile memory cell comprising a reduced height vertical diode
7560390 Multiple spacer steps for pitch multiplication

View more patents.

DARC results (if any) from reagent suppliers

Google CSE Logo
DARC antibody (ab40821) | Abcam
3 Apr 2007 ... Goat polyclonal to DARC. DARC is a non-specific receptor for many chemokines such as IL-8, GRO, RANTES, MCP-1 and TARC.
http://www.abcam.com/DARC-antibody-ab40821.html...

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DARC Antibody (CT) Duffy antigen/chemokine receptor
DARC antibody can be used for detection of DARC by Western blot at 1 – 2 μg/ml.,
http://www.prosci-inc.com/shop/catalog1/DARC-Antibody-p-6506...

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HPA017672 Anti-DARC antibody produced in rabbit Ab3, Prestige ...
HPA017672 Anti-DARC antibody produced in rabbit Ab3, Prestige Antibodies Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...

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DARC antibodies: Immunology > Innate Immunity > Chemokines > Alpha ...
DARC antibodies. ... DARC antibody. Flow Cyt, WB, ELISA, IHC-P. Images · Customer Abreviews: 4 stars (out of 5). Goat polyclonal ...
http://www.abcam.com/index.html?t=171701&pt=1&c=537&ei=&mu=r...

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Products :: ProSci Incorporated
DARC Antibody (CT) · BRSK2 Antibody · SCO1 Antibody · TIGAR Antibody (IN1) · TIGAR Antibody (IN2) · VISA Antibody (NT) · VISA Antibody (IN) ...
http://www.prosci-inc.com/shop/home.php...

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Duffy (F-20) Antibody sc-27817
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Mouse, Darc, 13349, 1 H3, Q9QUI6 ...
http://www.scbt.com/datasheet-27817-duffy-f-20-antibody.html...

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Cell Biology FOCUS
kines, and DARC binds both CXC and CC chemokines. ... Additionally, DARC on endothelial cells is proposed to bind chemokines and transport them ...
http://www.rndsystems.com/DAM_public/5882.pdf...

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