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RICTOR
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18089801 |
mTORC2 is hyperactivated in gliomas and promotes tumor cell proliferation and invasive potential due to increased complex formation as a result of the overexpression of rictor. |
| 17329400 |
ASCT2 silencing inhibits mTORC1 (mTOR/raptor) signaling and leads to growth repression, followed by enhanced survival signaling via mTORC2 (mTOR/rictor) and apoptosis of hepatoma cells. |
| 16962653 |
Results reveal that the SIN1-rictor-mTOR function in Akt-Ser473 phosphorylation is required for TORC2 function in cell survival but is dispensable for TORC1 function. |
| 17461779 |
It was demonstrated that immunoprecipitation of Protor-1 or Protor-2 results in the co-immunoprecipitation of other mTORC2 subunits, but not Raptor, a specific component of mTORC1. |
| 16959881 |
These data suggest that, during HCMV infection, the rictor- and raptor-containing complexes are modified such that their substrate specificities and rapamycin sensitivities are altered. |
| 15718470 |
results show show that target of rapamycin (TOR) kinase and its associated protein rictor are necessary for AKT/PKB Ser473 phosphorylation and that a reduction in rictor or mammalian TOR (mTOR) expression inhibited an Akt/PKB effector |
| 17043309 |
Sin1 together with Rictor are key components of mTORC2 and play an essential role in Akt phosphorylation and signaling |
RICTOR results (if any) from reagent suppliers | 
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