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XRCC6
| Symbol: | XRCC6 | | Name(s): | X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | CTC75, CTCBF, G22P1, KU70, ML8, TLAA | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 12750264 |
Observational study of gene-disease association. (HuGE Navigator) |
| 15958648 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17389609 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17768380 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17952468 |
Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) |
| 17971348 |
Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) |
| 18000863 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18208821 |
Autoantibodies against Ku are elicited by macromolecular protein complexes containing Ku and the associated DNA damage proteins may be involved of autoimmunity in rheumatic diseases. |
| 17982634 |
Expression of Ku70 in breast cancer tissue and normal breast tissue with immunohistochemistry are largely equal. |
| 17885668 |
These results indicate that Bax and Ku70 acetylation play important roles in Q79C-induced cell death, and that BIP may be useful in the development of therapeutics for polyQ diseases. | →View more information from publications. |
Recent Publications on XRCC6: |  |
Genotype-phenotype relationship between DNA repair gene genetic polymorphisms and DNA repair capacity.
Genotype-phenotype relationships between genetic polymorphisms of DNA... | 16th October, 2009
| Division of Cancer Prevention, National Cancer Control Research Institute,
| Asian Pac J Cancer Prev. 2008 Jul-Sep;9(3):501-5.
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A polymorphism in the promoter region of Ku70/XRCC6, associated with breast cancer risk and oestrogen exposure.
PURPOSE: Polymorphisms in double strand break repair genes could be... | 22nd August, 2009
| Department of Basic Medical Science, Ghent University, 9000 Ghent,
| J Cancer Res Clin Oncol. 2009 Sep;135(9):1159-68. Epub 2009 Feb 15.
DOI Direct Link |
Similarities and differences in the in vivo response of mouse neonatal gonocytes and spermatogonia to genotoxic stress.
Neonatal gonocytes are the precursors of both spermatogonial stem cells... | 20th June, 2009
| French Atomic Energy Commission, Fontenay aux Roses, France.
| Biol Reprod. 2009 May;80(5):860-73. Epub 2009 Jan 14.
DOI Direct Link |
Influence of multiple genetic polymorphisms on genitourinary morbidity after carbon ion radiotherapy for prostate cancer.
PURPOSE: To investigate the genetic risk of late urinary morbidity after... | 1st January, 2009
| RadGenomics Research Group, National Institute of Radiological Sciences,
| Int J Radiat Oncol Biol Phys. 2008 Nov 1;72(3):808-13. Epub 2008 Apr 18.
DOI Direct Link |
Transcriptome sequencing of malignant pleural mesothelioma tumors.
Cancers arise by the gradual accumulation of mutations in multiple genes.... | 19th April, 2008
| International Mesothelioma Program, Division of Thoracic Surgery,
| Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3521-6. Epub 2008 Feb 26.
DOI Direct Link |
→View more research publications. |
XRCC6 results (if any) from reagent suppliers | 
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Antibody Products - Protein and Antibody Solutions Provider - GenWay
Mouse monoclonal anti-human XRCC6 antibody; ATP-dependent DNA helicase II 70 kDa subunit; Lupus Ku autoantigen protein p70; Ku70; 70 kDa subunit of Ku ...
http://www.genwaybio.com/all_monoclonal_antibodies.php?fl=X...
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Antibodies to DNA Repair Proteins
Xrcc6(14375) human ... XRCC6(2547) rat ... Xrcc6(25019), human, rodent, IHC, WB, pricing. K3389, Anti-Ku80 (XRCC5) (322-337) antibody produced in rabbit ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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XRCC6 protein, Ku P70/P80 Human recombinant protein
Buy quality XRCC6 protein (insect (sf9 cells)), XRCC6, Ku P70/P80 Human recombinant protein, (n/an/a). Ku P70/P80 Human Recombinant; ATP-dependent DNA
...
http://www.genwaybio.com/product_info.php?products_id=45671...
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Ku-70/Ku-86 (3F247) Antibody sc-71471
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, XRCC6, 2547, 22q13.2, NM_001469 ...
http://www.scbt.com/datasheet-71471-ku-70-ku-86-3f247-antibo...
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DNA-PK antibody, DNA PKcs (Ab-2609) Antibody, Rabbit Polyclonal ...
Subunit: DNA-PK is a heterotrimer of PRKDC and the Ku p70-p86 (XRCC6-XRCC5) dimer. Formation of this complex may be promoted by interaction with ILF3. ...
http://www.genwaybio.com/product_info.php?products_id=210107...
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Ku-70/Ku-86 (SPM274) Antibody sc-65575
Mouse, Xrcc6, 14375, 15 E1, P23475, N/A. Mouse, Xrcc5, 22596, 1 C3, NM_009533, NM_010247 · P27641, N/A. Ordering Information. Product Name, Catalog #, Unit ...
http://www.scbt.com/datasheet-65575-ku-70-ku-86-spm274-antib...
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Antibodies to Nuclear Proteins
human ... XRCC6(2547), human, monkey, ARR, ICC, IF (i), IHC, IP, WB, pricing. L3414, Monoclonal Anti-LAP2 (TMPO) antibody produced in mouse, 6E10 ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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