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GABBR1


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Symbol:GABBR1
Name(s):gamma-aminobutyric acid (GABA) B receptor, 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:FLJ92613, GABAB(1e), GABABR1, GABBR1-3, GPRC3A, dJ271M21.1.1, dJ271M21.1.2, hGB1a
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18255321 Observational study of gene-disease association. (HuGE Navigator)
11140838 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
11844143 Observational study of gene-disease association. (HuGE Navigator)
12770685 Observational study of gene-disease association. (HuGE Navigator)
15309313 Observational study of gene-disease association. (HuGE Navigator)
15799783 Observational study of gene-disease association. (HuGE Navigator)
15820424 Observational study of gene-disease association. (HuGE Navigator)
15857448 Observational study of gene-disease association. (HuGE Navigator)
15946333 Observational study of gene-disease association. (HuGE Navigator)
16499773 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDGABA-B receptorG protein-coupled receptor 51--Pubmed
BIND-G protein-coupled receptor 51GB1 interacts with GB2.-Pubmed
HPRDGABA-B receptorjanus kinase and microtubule interacting protein 1 isoform 2--Pubmed
HPRDgamma-aminobutyric acid B receptor 1 isoform a precursorG protein coupled receptor 51--Pubmed
HPRDgamma-aminobutyric acid B receptor 1 isoform a precursorActivating transcription factor 5--Pubmed
HPRDgamma-aminobutyric acid B receptor 1 isoform a precursorMultiple coiled-coil GABABR1-binding protein--Pubmed

Recent Publications on GABBR1:

Pubmed Logo
[Genetics components in patients with temporal lobe epilepsy.]
INTRODUCTION. Epilepsy is one of the major neurological disorders...
28th October, 2009
Hospital Universitario de la Princesa, 28006 Madrid, Espana. Rev Neurol. 2009 Nov 16-30;49(10):541-6.
Nicotine response genetics in the zebrafish.
Tobacco use is predicted to result in over 1 billion deaths worldwide by...
28th October, 2009
University of Minnesota, Minneapolis, MN 55455. Proc Natl Acad Sci U S A. 2009 Oct 26.
DOI Direct Link
Genome-wide association study reveals multiple nasopharyngeal carcinoma-associated loci within the HLA region at chromosome 6p21.3.
Nasopharyngeal carcinoma (NPC) is a multifactorial malignancy closely...
24th September, 2009
Genomic Medicine Core, Chang Gung Molecular Medicine Research Center, Am J Hum Genet. 2009 Aug;85(2):194-203. Epub 2009 Aug 6.
DOI Direct Link
Association and interaction analyses of GABBR1 and GABBR2 with nicotine dependence in European- and African-American populations.
Previous studies have demonstrated that the gamma-aminobutyric acid type B...
19th September, 2009
Department of Psychiatry and Neurobehavioral Sciences, University of PLoS One. 2009 Sep 18;4(9):e7055.
DOI Direct Link
Expression of GABA(B) receptors is altered in brains of subjects with autism.
Autism is a neurodevelopmental disorder that is often comorbid with...
16th May, 2009
Department of Psychiatry, Division of Neuroscience Research, University of Cerebellum. 2009 Mar;8(1):64-9.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7598031 Method for the detection of gene transcripts in blood and uses thereof
7368264 SLC1A1 marker for anxiety disorder
7348140 Clinical indications for genotyping polymorphic variants of G-protein coupled receptors

GABBR1 results (if any) from reagent suppliers

Google CSE Logo
hGB1A antibody, Gamma-aminobutyric acid (GABA) B receptor 1 ...
Evidence for the gamma-amino-butyric acid type B receptor 1 (GABBR1) gene ... The GABBR1 locus and the G1465A variant is not associated with temporal lobe ...
http://www.genwaybio.com/product_info.php?products_id=10572...

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GABAB R1 (R-20) Antibody sc-7338
Human, GABBR1, 2550, 6p22.1, NM_001470, NM_021903, NM_021904, NM_021905 · Q9UBS5 · 603540. Mouse, Gabbr1, 54393, 17 B1, Q9WV18 ...
http://www.scbt.com/datasheet-7338-gabab-r1-r-20-antibody.ht...

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ATF-4 antibody, ATF4 (Ab-245) Antibody, Rabbit Polyclonal Antibody
Subunit: Interacts with the C-terminal region of GABBR1 via the leucine ... Note =Colocalizes with GABBR1 in hippocampal neuron dendritic membranes (By ...
http://www.genwaybio.com/product_info.php?products_id=210034...

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p-GABAB R1 (Ser 923) Antibody sc-135694
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, GABBR1, 2550, 6p22.1, Q9UBS5 ...
http://www.scbt.com/datasheet-135694-p-gabab-r1-ser-923-anti...

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A2129 γ-Aminobutyric acid GABA ≥99%
GABBR1(2550), GABBR2(9568), GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4( 2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=A212...

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B5399 (±)-Baclofen ≥98% (TLC), solid
solubility, 1 M HCl: 50 mg/mL. Gene Information, human ... GABBR1(2550), GABBR2( 9568). rat ... Gabbr1(81657), Gabra2(29706). storage temp. 2-8°C ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...

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UC429 Midazolam hydrochloride solid
Gene Information, human ... ABCB1(5243), CYP3A4(1576). rat ... Gabbr1(81657), Gabra1(29705). mouse ... Abcb1a(18671), Abcb1b(18669). storage temp. 2-8°C ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=UC42...

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