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GABPA


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Gene DB Home
Symbol:GABPA
Name(s):GA binding protein transcription factor, alpha subunit 60kDa
Type:protein-coding
Organism:Homo sapiens
Synonyms:E4TF1-60, E4TF1A, NFT2, NRF2, NRF2A
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
15358217 Observational study of genotype prevalence. (HuGE Navigator)
17357964 The researchers found that NRF2 polymorphisms may explain some of the variation in endurance capacity in different persons.
17357964 The researchers found that NRF2 polymorphisms may explain some of the variation in endurance capacity in different persons.
17161026 NRF-2 may play a key role in the regulation of mitochondrial protein synthesis in a cell line.
15361867 GABP is essential for the regulation of IL-7Ralpha expression in T cells.
15928042 there is a physical interaction between the GABPalpha subunit and C/EBPalpha
16574658 TRAP220/MED1 plays a novel coregulatory role in facilitating the recruitment of TRAP/Mediator to specific target genes involved in growth and cell cycle progression via GABP
16581781 GABPA and p300 are essential components of retinoic acid-induced enhanceosome in myeloid cells.
17304221 Upon activation of AChR, GABP recruits the histone acetyl transferase (HAT) p300 on the AChR epsilon subunit promoter, whereas it rather recruits the histone deacetylase HDAC1 when the promoter is not activated.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDActivating transcription factor 1GA binding protein transcription factor, alpha subunit--Pubmed
HPRDGA binding protein transcription factor, alpha subunitHost cell factor C1--Pubmed
HPRDGA binding protein transcription factor, alpha subunitTranscription factor Sp3--Pubmed
HPRDGA binding protein transcription factor, alpha subunitGA binding protein transcription factor, beta subunit 2 isoform beta 1--Pubmed
HPRDGA binding protein transcription factor, alpha subunitGA binding protein transcription factor, beta subunit 2 isoform beta 1--Pubmed
HPRDGA binding protein transcription factor, alpha subunitSp1 transcription factor--Pubmed

Recent Publications on GABPA:

Pubmed Logo
Death-associated protein 3 is overexpressed in human thyroid oncocytic tumours.
BACKGROUND: The human death-associated protein 3 (hDAP3) is a GTP-binding...
9th July, 2009
INSERM, U694, Centre Hospitalier Universitaire d'Angers, Laboratoire de Br J Cancer. 2009 Jul 7;101(1):132-8. Epub 2009 Jun 16.
DOI Direct Link
Methylation-sensitive regulation of TMS1/ASC by the Ets factor, GA-binding protein-alpha.
Epigenetic silencing involving the aberrant DNA methylation of...
30th June, 2009
Graduate Program in Genetics and Molecular Biology, the Winship Cancer J Biol Chem. 2009 May 29;284(22):14698-709. Epub 2009 Mar 25.
DOI Direct Link
Chemical genomics of cancer chemopreventive dithiolethiones.
3H-1,2-dithiole-3-thione (D3T) and its analogues...
11th April, 2009
Department of Mathematical Sciences, University of Memphis, Memphis, TN Carcinogenesis. 2009 Mar;30(3):480-6. Epub 2009 Jan 6.
DOI Direct Link
Mitochondrial DNA content, an inaccurate biomarker of mitochondrial alteration in human immunodeficiency virus-related lipodystrophy.
Lipoatrophy is a prevalent side effect of antiretroviral treatment of...
14th August, 2008
Inserm, U582, Paris, F-75013 France. Antimicrob Agents Chemother. 2008 May;52(5):1670-6. Epub 2008 Mar 10.
DOI Direct Link
Cooperative regulation of Fc receptor gamma-chain gene expression by multiple transcription factors, including Sp1, GABP, and Elf-1.
The Fc receptor gamma-chain (FcRgamma), which was first identified as a...
18th July, 2008
Department of Molecular Cell Immunology and Allergology, Nihon University J Biol Chem. 2008 May 30;283(22):15134-41. Epub 2008 Mar 31.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7588771 Microorganisms for therapy
7588767 Microorganisms for therapy
7544838 Ligands for estrogen related receptors and methods for synthesis of said ligands
7381526 Assays for drug discovery based on microcompetition with a foreign polynucleotide
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector

View more patents.

GABPA results (if any) from reagent suppliers

Google CSE Logo
GABPA antibodies: Chromatin and Nuclear Signaling > ChIP'ing ...
GABPA antibodies. ... GABPA antibody - ChIP Grade. IHC-P, WB, ChIP. Images · Customer Abreviews: 4 stars (out of 5) · Specific publication references ...
http://www.abcam.com/index.html?t=118429&pt=1&c=4580&ei=&mu=...

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GABP-α (G-1) Antibody sc-28312
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, GABPA, 2551, 21q21.3, NM_002040 ...
http://www.scbt.com/datasheet-28312-gabp-alpha-g-1-antibody....

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Abgent - Transcription and Regulation Antibodies ...
AT2139aNEW, GABPA monoclonal antibody (M03), ELISA,IF,S-ELISA,WB-Ce,WB-Re, H. AT2140aNEW, GABPA monoclonal antibody (M04), ELISA,IF,IHC-P,WB-Ce,WB-Re, H ...
http://www.abgent.com/products/category/nuclear_signaling/tr...

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GABP-α (H-2) Antibody sc-28311
Spezies, Gen, Gen ID, Chromosomaler Locus, mRNA (Isoform) Accession #, Protein Accession #, OMIM™ Nummer. Human, GABPA, 2551, 21q21.3, NM_002040 · Q06546 ...
http://www.scbt.com/de/datasheet-28311-gabp-alpha-h-2-antibo...

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Abcam antibodies and reagents product map
... FOXO3A antibodies · FOXP3 antibodies · GABPA antibodies · GAL4 antibodies · GATA1 antibodies · GATA2 antibodies · Glucocorticoid Receptor antibodies ...
http://www.abcam.com/index.html?pageconfig=productmap&Cl=917...

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GABP-α (G-1) Antibody sc-28312
种属, 基因名称, 基因ID, 染色质位置, 亚型(mRNA)即位号码, 蛋白质即位号码, OMIM™ 号码. 人类, GABPA, 2551, 21q21.3, NM_002040 · Q06546 ...
http://www.scbt.com/zh/datasheet-28312-gabp-alpha-g-1-antibo...

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Abcam antibodies and reagents product map
... FOXC1 antibodies (1) · FOXC2 antibodies (1) · FOXK1 antibodies (1) · FOXO3A antibodies (1) · FOXP3 antibodies (1) · GABPA antibodies (1) ...
http://www.abcam.com/index.html?c=250...

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